Project measure / variable:   Neuner1   epm_open_time_14mo

ID, description, units MPD:65961   epm_open_time_14mo   percentage of time spent in open arms of elevated plus maze, 6 min test   [%]  14 mo  
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 23-57wks
Procedure elevated plus maze
Ontology mappings

  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent in open arms of elevated plus maze, 6 min test 14 mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested49 strains35 strains
Mean of the strain means22.732   % 21.622   %
Median of the strain means15.636   % 16.625   %
SD of the strain means± 20.303 ± 15.64
Coefficient of variation (CV)0.8931 0.7233
Min–max range of strain means0.0   –   93.0   % 1.5   –   49.667   %
Mean sample size per strain4.6   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 157.0358 157.0358 0.4106 0.5223
strain 25 39309.5895 1572.3836 4.1113 < 0.0001
sex:strain 25 6451.7966 258.0719 0.6748 0.8789
Residuals 231 88346.1293 382.4508


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f 83.0 0.0   1   0.0 0.0 83.0, 83.0 2.97
(B6.5XFAD x B6)F1-ADtg m 47.75 32.208   32 5.6936 0.6745 1.67
(B6.5XFAD x B6)F1-Ntg f 15.636 18.14   11 5.4694 1.1601 -0.35
(B6.5XFAD x B6)F1-Ntg m 8.8462 11.803   13 3.2735 1.3342 -0.82
(B6.5XFAD x BXD100)F1-ADtg f 5.5 2.1213   2   1.5 0.3857 4.0, 7.0 -0.85
(B6.5XFAD x BXD100)F1-ADtg m 12.0 14.166   7 5.3541 1.1805 2.0, 43.0 -0.62
(B6.5XFAD x BXD100)F1-Ntg f 9.0 4.2426   4 2.1213 0.4714 4.0, 13.0 -0.68
(B6.5XFAD x BXD100)F1-Ntg m 5.3333 4.5461   6 1.8559 0.8524 -1.04
(B6.5XFAD x BXD14)F1-ADtg f 93.0 15.556   2   11.0 0.1673 82.0, 104.0 3.46
(B6.5XFAD x BXD14)F1-Ntg f 16.0 15.556   2   11.0 0.9723 5.0, 27.0 -0.33
(B6.5XFAD x BXD16)F1-ADtg f 39.75 27.097   4 13.549 0.6817 11.0, 68.0 0.84
(B6.5XFAD x BXD22)F1-ADtg f 27.5 17.678   2   12.5 0.6428 15.0, 40.0 0.23
(B6.5XFAD x BXD22)F1-Ntg f 2.0 3.4641   3 2.0 1.7321 -1.02
(B6.5XFAD x BXD32)F1-ADtg f 22.0 30.643   3 17.692 1.3929 -0.04
(B6.5XFAD x BXD32)F1-ADtg m 48.0 15.588   3 9.0 0.3248 39.0, 66.0 1.69
(B6.5XFAD x BXD32)F1-Ntg f 10.667 1.5275   3 0.88192 0.1432 9.0, 12.0 -0.59
(B6.5XFAD x BXD32)F1-Ntg m 28.0 32.527   2   23.0 1.1617 5.0, 51.0 0.41
(B6.5XFAD x BXD42)F1-ADtg f 36.0 31.113   2   22.0 0.8642 14.0, 58.0 0.65
(B6.5XFAD x BXD42)F1-Ntg f 0.0 0.0   1   0.0 None -1.12
(B6.5XFAD x BXD44)F1-ADtg f 25.917 22.693   12 6.551 0.8756 0.16
(B6.5XFAD x BXD44)F1-ADtg m 16.625 14.081   8 4.9783 0.847 1.0, 45.0 -0.32
(B6.5XFAD x BXD44)F1-Ntg f 13.0 0.0   1   0.0 0.0 13.0, 13.0 -0.48
(B6.5XFAD x BXD44)F1-Ntg m 5.0 2.6458   3 1.5275 0.5292 3.0, 8.0 -1.06
(B6.5XFAD x BXD51)F1-ADtg f 33.8 11.904   5 5.3235 0.3522 15.0, 46.0 0.55
(B6.5XFAD x BXD51)F1-Ntg f 13.25 11.673   4 5.8363 0.881 3.0, 29.0 -0.47
(B6.5XFAD x BXD55)F1-ADtg f 52.0 27.952   4 13.976 0.5375 12.0, 74.0 1.44
(B6.5XFAD x BXD55)F1-Ntg f 0.0 0.0   2   0.0 None -1.12
(B6.5XFAD x BXD56)F1-ADtg m 39.667 30.616   3 17.676 0.7718 5.0, 63.0 1.15
(B6.5XFAD x BXD56)F1-Ntg f 4.0 4.2426   2   3.0 1.0607 1.0, 7.0 -0.92
(B6.5XFAD x BXD56)F1-Ntg m 12.0 0.0   1   0.0 0.0 12.0, 12.0 -0.62
(B6.5XFAD x BXD60)F1-ADtg f 45.0 30.8   4 15.4 0.6845 21.0, 90.0 1.1
(B6.5XFAD x BXD60)F1-ADtg m 23.4 24.896   5 11.134 1.0639 0.11
(B6.5XFAD x BXD60)F1-Ntg f 4.3333 7.5056   3 4.3333 1.7321 -0.91
(B6.5XFAD x BXD61)F1-ADtg f 35.429 29.782   7 11.256 0.8406 6.0, 73.0 0.63
(B6.5XFAD x BXD61)F1-ADtg m 33.333 29.263   3 16.895 0.8779 1.0, 58.0 0.75
(B6.5XFAD x BXD61)F1-Ntg f 2.4 2.881   5 1.2884 1.2004 -1.0
(B6.5XFAD x BXD61)F1-Ntg m 11.167 15.184   6 6.199 1.3598 1.0, 41.0 -0.67
(B6.5XFAD x BXD62)F1-ADtg f 50.33 32.578   3 18.809 0.6472 13.0, 73.0 1.36
(B6.5XFAD x BXD62)F1-ADtg m 35.0 0.0   2   0.0 0.0 35.0, 35.0 0.86
(B6.5XFAD x BXD62)F1-Ntg f 5.0 1.7321   3 1.0 0.3464 4.0, 7.0 -0.87
(B6.5XFAD x BXD62)F1-Ntg m 5.0 8.6603   3 5.0 1.7321 -1.06
(B6.5XFAD x BXD65)F1-ADtg f 27.571 26.349   7 9.9591 0.9557 0.24
(B6.5XFAD x BXD65)F1-ADtg m 37.5 19.092   2   13.5 0.5091 24.0, 51.0 1.02
(B6.5XFAD x BXD65)F1-Ntg f 15.25 22.167   8 7.8371 1.4535 -0.37
(B6.5XFAD x BXD65)F1-Ntg m 1.5 0.70711   2   0.5 0.4714 1.0, 2.0 -1.29
(B6.5XFAD x BXD66)F1-ADtg f 40.333 33.02   3 19.064 0.8187 8.0, 74.0 0.87
(B6.5XFAD x BXD66)F1-ADtg m 26.8 42.293   5 18.914 1.5781 2.0, 100.0 0.33
(B6.5XFAD x BXD66)F1-Ntg f 29.0 0.0   1   0.0 0.0 29.0, 29.0 0.31
(B6.5XFAD x BXD66)F1-Ntg m 5.5 7.7782   2   5.5 1.4142 -1.03
(B6.5XFAD x BXD68)F1-ADtg f 29.0 25.159   3 14.526 0.8676 13.0, 58.0 0.31
(B6.5XFAD x BXD68)F1-ADtg m 36.429 15.863   7 5.9955 0.4354 22.0, 68.0 0.95
(B6.5XFAD x BXD68)F1-Ntg f 14.8 9.9978   10 3.1616 0.6755 -0.39
(B6.5XFAD x BXD68)F1-Ntg m 12.5 14.849   2   10.5 1.1879 2.0, 23.0 -0.58
(B6.5XFAD x BXD69)F1-ADtg f 15.2 15.189   5 6.7926 0.9993 -0.37
(B6.5XFAD x BXD69)F1-ADtg m 16.0 17.986   5 8.0436 1.1241 6.0, 48.0 -0.36
(B6.5XFAD x BXD69)F1-Ntg f 7.75 7.8049   4 3.9025 1.0071 1.0, 19.0 -0.74
(B6.5XFAD x BXD69)F1-Ntg m 5.8333 5.9133   6 2.4141 1.0137 -1.01
(B6.5XFAD x BXD70)F1-ADtg f 45.0 0.0   1   0.0 0.0 45.0, 45.0 1.1
(B6.5XFAD x BXD70)F1-ADtg m 49.667 43.132   3 24.902 0.8684 2.0, 86.0 1.79
(B6.5XFAD x BXD70)F1-Ntg f 6.0 7.2111   3 4.1633 1.2019 -0.82
(B6.5XFAD x BXD70)F1-Ntg m 7.5 6.364   2   4.5 0.8485 3.0, 12.0 -0.9
(B6.5XFAD x BXD75)F1-ADtg f 50.0 32.853   4 16.427 0.6571 7.0, 87.0 1.34
(B6.5XFAD x BXD75)F1-ADtg m 38.0 25.573   4 12.787 0.673 9.0, 60.0 1.05
(B6.5XFAD x BXD75)F1-Ntg f 10.5 20.936   6 8.5469 1.9939 -0.6
(B6.5XFAD x BXD75)F1-Ntg m 11.0 0.0   1   0.0 0.0 11.0, 11.0 -0.68
(B6.5XFAD x BXD77)F1-ADtg f 28.2 24.17   5 10.809 0.8571 2.0, 58.0 0.27
(B6.5XFAD x BXD77)F1-ADtg m 27.667 18.556   3 10.713 0.6707 10.0, 47.0 0.39
(B6.5XFAD x BXD77)F1-Ntg f 10.3 8.1656   10 2.5822 0.7928 1.0, 29.0 -0.61
(B6.5XFAD x BXD77)F1-Ntg m 3.5 2.8107   6 1.1475 0.8031 -1.16
(B6.5XFAD x BXD81)F1-ADtg f 35.167 27.396   6 11.185 0.779 0.61
(B6.5XFAD x BXD81)F1-Ntg f 13.4 13.372   5 5.98 0.9979 -0.46
(B6.5XFAD x BXD87)F1-ADtg f 33.889 26.299   9 8.7662 0.776 0.55
(B6.5XFAD x BXD87)F1-ADtg m 41.75 29.136   4 14.568 0.6979 18.0, 83.0 1.29
(B6.5XFAD x BXD87)F1-Ntg f 0.33333 0.57735   3 0.33333 1.7321 -1.1
(B6.5XFAD x BXD87)F1-Ntg m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -1.25
(B6.5XFAD x BXD89)F1-ADtg m 39.0 0.0   1   0.0 0.0 39.0, 39.0 1.11
(B6.5XFAD x BXD89)F1-Ntg f 1.5 2.1213   2   1.5 1.4142 -1.05
(B6.5XFAD x BXD89)F1-Ntg m 37.5 30.406   2   21.5 0.8108 16.0, 59.0 1.02
(B6.5XFAD x BXD99)F1-ADtg f 20.0 0.0   1   0.0 0.0 20.0, 20.0 -0.13
(B6.5XFAD x BXD99)F1-Ntg f 10.0 0.0   1   0.0 0.0 10.0, 10.0 -0.63
(B6.5XFAD x D2)F1-ADtg f 22.789 24.654   19 5.6561 1.0818 0.0
(B6.5XFAD x D2)F1-ADtg m 23.0 19.625   8 6.9385 0.8533 0.09
(B6.5XFAD x D2)F1-Ntg f 3.3846 4.3692   13 1.2118 1.2909 -0.95
(B6.5XFAD x D2)F1-Ntg m 3.0 3.6742   5 1.6432 1.2247 -1.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f 15.6364 5.8965 27.2541 4.0186
(B6.5XFAD x B6)F1-Ntg m 8.8462 5.424 19.5329 -1.8406
(B6.5XFAD x BXD100)F1-ADtg f 5.5 13.8284 32.746 -21.746
(B6.5XFAD x BXD100)F1-ADtg m 12.0 7.3916 26.5636 -2.5636
(B6.5XFAD x BXD100)F1-Ntg f 9.0 9.7782 28.2658 -10.2658
(B6.5XFAD x BXD100)F1-Ntg m 5.3333 7.9838 21.0638 -10.3971
(B6.5XFAD x BXD32)F1-ADtg f 22.0 11.2909 44.2462 -0.2462
(B6.5XFAD x BXD32)F1-ADtg m 48.0 11.2909 70.2462 25.7538
(B6.5XFAD x BXD32)F1-Ntg f 10.6667 11.2909 32.9129 -11.5796
(B6.5XFAD x BXD32)F1-Ntg m 28.0 13.8284 55.246 0.754
(B6.5XFAD x BXD44)F1-ADtg f 25.9167 5.6454 37.0398 14.7935
(B6.5XFAD x BXD44)F1-ADtg m 16.625 6.9142 30.248 3.002
(B6.5XFAD x BXD60)F1-ADtg f 45.0 9.7782 64.2658 25.7342
(B6.5XFAD x BXD60)F1-ADtg m 23.4 8.7459 40.6319 6.1681
(B6.5XFAD x BXD61)F1-ADtg f 35.4286 7.3916 49.9922 20.865
(B6.5XFAD x BXD61)F1-ADtg m 33.3333 11.2909 55.5796 11.0871
(B6.5XFAD x BXD61)F1-Ntg f 2.4 8.7459 19.6319 -14.8319
(B6.5XFAD x BXD61)F1-Ntg m 11.1667 7.9838 26.8971 -4.5638
(B6.5XFAD x BXD62)F1-ADtg f 50.3333 11.2909 72.5796 28.0871
(B6.5XFAD x BXD62)F1-ADtg m 35.0 13.8284 62.246 7.754
(B6.5XFAD x BXD62)F1-Ntg f 5.0 11.2909 27.2462 -17.2462
(B6.5XFAD x BXD62)F1-Ntg m 5.0 11.2909 27.2462 -17.2462
(B6.5XFAD x BXD65)F1-ADtg f 27.5714 7.3916 42.135 13.0078
(B6.5XFAD x BXD65)F1-ADtg m 37.5 13.8284 64.746 10.254
(B6.5XFAD x BXD65)F1-Ntg f 15.25 6.9142 28.873 1.627
(B6.5XFAD x BXD65)F1-Ntg m 1.5 13.8284 28.746 -25.746
(B6.5XFAD x BXD66)F1-ADtg f 40.3333 11.2909 62.5796 18.0871
(B6.5XFAD x BXD66)F1-ADtg m 26.8 8.7459 44.0319 9.5681
(B6.5XFAD x BXD68)F1-ADtg f 29.0 11.2909 51.2462 6.7538
(B6.5XFAD x BXD68)F1-ADtg m 36.4286 7.3916 50.9922 21.865
(B6.5XFAD x BXD68)F1-Ntg f 14.8 6.1843 26.9848 2.6152
(B6.5XFAD x BXD68)F1-Ntg m 12.5 13.8284 39.746 -14.746
(B6.5XFAD x BXD69)F1-ADtg f 15.2 8.7459 32.4319 -2.0319
(B6.5XFAD x BXD69)F1-ADtg m 16.0 8.7459 33.2319 -1.2319
(B6.5XFAD x BXD69)F1-Ntg f 7.75 9.7782 27.0158 -11.5158
(B6.5XFAD x BXD69)F1-Ntg m 5.8333 7.9838 21.5638 -9.8971
(B6.5XFAD x BXD70)F1-Ntg f 6.0 11.2909 28.2462 -16.2462
(B6.5XFAD x BXD70)F1-Ntg m 7.5 13.8284 34.746 -19.746
(B6.5XFAD x BXD75)F1-ADtg f 50.0 9.7782 69.2658 30.7342
(B6.5XFAD x BXD75)F1-ADtg m 38.0 9.7782 57.2658 18.7342
(B6.5XFAD x BXD77)F1-ADtg f 28.2 8.7459 45.4319 10.9681
(B6.5XFAD x BXD77)F1-ADtg m 27.6667 11.2909 49.9129 5.4204
(B6.5XFAD x BXD77)F1-Ntg f 10.3 6.1843 22.4848 -1.8848
(B6.5XFAD x BXD77)F1-Ntg m 3.5 7.9838 19.2305 -12.2305
(B6.5XFAD x BXD87)F1-ADtg f 33.8889 6.5188 46.7328 21.045
(B6.5XFAD x BXD87)F1-ADtg m 41.75 9.7782 61.0158 22.4842
(B6.5XFAD x BXD89)F1-Ntg f 1.5 13.8284 28.746 -25.746
(B6.5XFAD x BXD89)F1-Ntg m 37.5 13.8284 64.746 10.254
(B6.5XFAD x D2)F1-ADtg f 22.7895 4.4865 31.6292 13.9497
(B6.5XFAD x D2)F1-ADtg m 23.0 6.9142 36.623 9.377
(B6.5XFAD x D2)F1-Ntg f 3.3846 5.424 14.0714 -7.3021
(B6.5XFAD x D2)F1-Ntg m 3.0 8.7459 20.2319 -14.2319


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both 12.2413 4.0059 20.1339 4.3486
(B6.5XFAD x BXD100)F1-ADtg both 8.75 7.84 24.197 -6.697
(B6.5XFAD x BXD100)F1-Ntg both 7.1667 6.3118 19.6027 -5.2694
(B6.5XFAD x BXD32)F1-ADtg both 35.0 7.9838 50.7305 19.2695
(B6.5XFAD x BXD32)F1-Ntg both 19.3333 8.9262 36.9205 1.7461
(B6.5XFAD x BXD44)F1-ADtg both 21.2708 4.4631 30.0644 12.4772
(B6.5XFAD x BXD60)F1-ADtg both 34.2 6.5594 47.1239 21.2761
(B6.5XFAD x BXD61)F1-ADtg both 34.381 6.7476 47.6756 21.0863
(B6.5XFAD x BXD61)F1-Ntg both 6.7833 5.921 18.4494 -4.8827
(B6.5XFAD x BXD62)F1-ADtg both 42.6667 8.9262 60.2539 25.0795
(B6.5XFAD x BXD62)F1-Ntg both 5.0 7.9838 20.7305 -10.7305
(B6.5XFAD x BXD65)F1-ADtg both 32.5357 7.84 47.9827 17.0887
(B6.5XFAD x BXD65)F1-Ntg both 8.375 7.7303 23.606 -6.856
(B6.5XFAD x BXD66)F1-ADtg both 33.5667 7.141 47.6364 19.4969
(B6.5XFAD x BXD68)F1-ADtg both 32.7143 6.7476 46.009 19.4196
(B6.5XFAD x BXD68)F1-Ntg both 13.65 7.5741 28.5732 -1.2732
(B6.5XFAD x BXD69)F1-ADtg both 15.6 6.1843 27.7848 3.4152
(B6.5XFAD x BXD69)F1-Ntg both 6.7917 6.3118 19.2277 -5.6444
(B6.5XFAD x BXD70)F1-Ntg both 6.75 8.9262 24.3372 -10.8372
(B6.5XFAD x BXD75)F1-ADtg both 44.0 6.9142 57.623 30.377
(B6.5XFAD x BXD77)F1-ADtg both 27.9333 7.141 42.0031 13.8636
(B6.5XFAD x BXD77)F1-Ntg both 6.9 5.0494 16.8488 -3.0488
(B6.5XFAD x BXD87)F1-ADtg both 37.8194 5.876 49.3968 26.2421
(B6.5XFAD x BXD89)F1-Ntg both 19.5 9.7782 38.7658 0.2342
(B6.5XFAD x D2)F1-ADtg both 22.8947 4.1211 31.0146 14.7749
(B6.5XFAD x D2)F1-Ntg both 3.1923 5.1456 13.3306 -6.946




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA