Project measure / variable:   Brinkmeyer1   clin_score_d6

ID, description, units MPD:64420   clin_score_d6   clinical score (0=normal, 6=moribund), post infection   [score]  day 6  
Theiler's murine encephalomyelitis virus study
Data set, strains Brinkmeyer1   CC   5 strains     sex: both     age: 4wks
Procedure health assessment
Ontology mappings

  STRAIN COMPARISON PLOT
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Brinkmeyer1 - clinical score (0=normal, 6=moribund), post infection day 6



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains4 strains
Mean of the strain means1.44   score 1.875   score
Median of the strain means1.5   score 2.1   score
SD of the strain means± 0.81731 ± 0.59652
Coefficient of variation (CV)0.5676 0.3181
Min–max range of strain means0.5   –   2.7   score 1.0   –   2.3   score
Mean sample size per strain3.8   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0211 0.0211 0.0298 0.8653
strain 1 2.8471 2.8471 4.0289 0.0631
sex:strain 1 0.9529 0.9529 1.3485 0.2637
Residuals 15 10.6 0.7067


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC013/GeniUnc f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.54
CC013/GeniUnc m 2.2 0.44721   5 0.2 0.2033 2.0, 3.0 0.54
CC016/GeniUnc f 0.5 0.70711   2   0.5 1.4142 -1.15
CC019/TauUnc f 2.7 0.67082   5 0.3 0.2485 2.0, 3.5 1.54
CC019/TauUnc m 2.3 1.2042   5 0.53852 0.5235 1.0, 3.5 0.71
CC041/TauUnc f 1.5 0.54772   6 0.22361 0.3651 1.0, 2.0 0.07
CC041/TauUnc m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.47
CC061/GeniUnc f 1.5 0.86603   5 0.3873 0.5774 1.0, 3.0 0.07
CC061/GeniUnc m 2.0 0.0   4 0.0 0.0 2.0, 2.0 0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC019/TauUnc f 2.7 0.3759432581 3.5013040867 1.8986959133
CC019/TauUnc m 2.3 0.3759432581 3.1013040867 1.4986959133
CC061/GeniUnc f 1.5 0.3759432581 2.3013040867 0.6986959133
CC061/GeniUnc m 2.0 0.4203173404 2.8958852043 1.1041147957


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC019/TauUnc both 2.5 0.2658320272 3.0666075535 1.9333924465
CC061/GeniUnc both 1.75 0.2819574436 2.350978065 1.149021935




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA