Project measure / variable:   Brinkmeyer1   clin_score_d2

ID, description, units MPD:64418   clin_score_d2   clinical score (0=normal, 6=moribund), post infection   [score]  day 2  
Theiler's murine encephalomyelitis virus study
Data set, strains Brinkmeyer1   CC   5 strains     sex: both     age: 4wks
Procedure health assessment
Ontology mappings

  STRAIN COMPARISON PLOT
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Brinkmeyer1 - clinical score (0=normal, 6=moribund), post infection day 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains4 strains
Mean of the strain means1.2048   score 1.0917   score
Median of the strain means1.4167   score 0.93334   score
SD of the strain means± 0.79795 ± 0.67515
Coefficient of variation (CV)0.6623 0.6185
Min–max range of strain means0.0   –   2.0   score 0.5   –   2.0   score
Mean sample size per strain4.6   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.3581 2.3581 4.6946 0.0378
strain 3 1.9011 0.6337 1.2616 0.3041
sex:strain 3 5.767 1.9223 3.827 0.0189
Residuals 32 16.0738 0.5023


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC013/GeniUnc f 2.0 0.0   2   0.0 0.0 2.0, 2.0 1.0
CC013/GeniUnc m 0.66667 1.0328   6 0.42164 1.5492 -0.63
CC016/GeniUnc f 0.0 0.0   2   0.0 None -1.51
CC019/TauUnc f 1.4167 0.58452   6 0.23863 0.4126 1.0, 2.5 0.27
CC019/TauUnc m 0.5 0.54772   6 0.22361 1.0954 -0.88
CC041/TauUnc f 0.85714 1.069   7 0.40406 1.2472 -0.44
CC041/TauUnc m 2.0 0.0   2   0.0 0.0 2.0, 2.0 1.35
CC061/GeniUnc f 1.75 0.27386   6 0.1118 0.1565 1.5, 2.0 0.68
CC061/GeniUnc m 1.2 0.27386   5 0.12247 0.2282 1.0, 1.5 0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC013/GeniUnc f 2.0 0.5011519468 3.0208131106 0.9791868894
CC013/GeniUnc m 0.6666666667 0.2893402114 1.2560333909 0.0772999424
CC019/TauUnc f 1.4166666667 0.2893402114 2.0060333909 0.8272999424
CC019/TauUnc m 0.5 0.2893402114 1.0893667242 -0.0893667242
CC041/TauUnc f 0.8571428571 0.2678769834 1.4027904166 0.3114952977
CC041/TauUnc m 2.0 0.5011519468 3.0208131106 0.9791868894
CC061/GeniUnc f 1.75 0.2893402114 2.3393667242 1.1606332758
CC061/GeniUnc m 1.2 0.3169563212 1.845618899 0.554381101


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC013/GeniUnc both 1.3333333333 0.2893402114 1.9227000576 0.7439666091
CC019/TauUnc both 0.9583333333 0.2045944256 1.3750785406 0.541588126
CC041/TauUnc both 1.4285714286 0.2841264472 2.0073180627 0.8498247945
CC061/GeniUnc both 1.475 0.2145804438 1.9120860608 1.0379139392




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA