Project measure / variable:   Bolivar2   act_shock_3

ID, description, units MPD:63904   act_shock_3   activity (beam breaks) during 2.5 min period of training on day 1   [n]  after 3rd shock  
Data set, strains Bolivar2   inbred   8 strains     sex: both     age: 9-20wks
Procedure fear conditioning test
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  STRAIN COMPARISON PLOT
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Bolivar2 - activity (beam breaks) during 2.5 min period of training on day 1 after 3rd shock



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means40.25   n 46.112   n
Median of the strain means43.978   n 45.6   n
SD of the strain means± 11.046 ± 12.962
Coefficient of variation (CV)0.2744 0.2811
Min–max range of strain means22.533   –   51.51   n 21.622   –   65.67   n
Mean sample size per strain18.0   mice 18.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2473.3889 2473.3889 7.7033 0.0059
strain 7 21236.2733 3033.7533 9.4486 < 0.0001
sex:strain 7 15302.6911 2186.0987 6.8086 < 0.0001
Residuals 272 87334.0978 321.0812


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 22.533 7.7466   18 1.8259 0.3438 12.4, 36.0 -1.6
129S1/SvImJ m 21.622 8.8101   18 2.0766 0.4075 7.6, 46.4 -1.89
A/J f 41.8 17.228   18 4.0607 0.4122 16.0, 73.2 0.14
A/J m 43.978 16.176   18 3.8127 0.3678 12.8, 68.4 -0.16
BALB/cByJ f 46.667 14.356   18 3.3838 0.3076 21.2, 78.8 0.58
BALB/cByJ m 47.222 19.879   18 4.6856 0.421 18.0, 99.6 0.09
C3H/HeJ f 37.089 14.379   18 3.3891 0.3877 12.8, 59.6 -0.29
C3H/HeJ m 50.16 20.323   18 4.7901 0.4052 22.4, 97.2 0.31
C57BL/6J f 46.156 15.861   18 3.7384 0.3436 19.6, 78.4 0.53
C57BL/6J m 43.333 15.075   18 3.5532 0.3479 18.8, 68.0 -0.21
CBA/J f 51.51 20.508   18 4.8338 0.3981 23.2, 86.4 1.02
CBA/J m 39.711 13.104   18 3.0887 0.33 19.6, 69.2 -0.49
DBA/2J f 25.556 10.147   18 2.3917 0.3971 8.4, 43.2 -1.33
DBA/2J m 65.67 34.308   18 8.0865 0.5225 19.6, 119.2 1.51
FVB/NJ f 50.69 21.983   18 5.1813 0.4337 20.0, 110.4 0.95
FVB/NJ m 57.2 19.641   18 4.6294 0.3434 36.0, 100.0 0.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 22.5333 4.2235 30.8482 14.2185
129S1/SvImJ m 21.6222 4.2235 29.9371 13.3073
A/J f 41.8 4.2235 50.1149 33.4851
A/J m 43.9778 4.2235 52.2927 35.6629
BALB/cByJ f 46.6667 4.2235 54.9815 38.3518
BALB/cByJ m 47.2222 4.2235 55.5371 38.9073
C3H/HeJ f 37.0889 4.2235 45.4038 28.774
C3H/HeJ m 50.1556 4.2235 58.4704 41.8407
C57BL/6J f 46.1556 4.2235 54.4704 37.8407
C57BL/6J m 43.3333 4.2235 51.6482 35.0185
CBA/J f 51.5111 4.2235 59.826 43.1962
CBA/J m 39.7111 4.2235 48.026 31.3962
DBA/2J f 25.5556 4.2235 33.8704 17.2407
DBA/2J m 65.6667 4.2235 73.9815 57.3518
FVB/NJ f 50.6889 4.2235 59.0038 42.374
FVB/NJ m 57.2 4.2235 65.5149 48.8851


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 22.0778 2.9865 27.9573 16.1983
A/J both 42.8889 2.9865 48.7684 37.0094
BALB/cByJ both 46.9444 2.9865 52.824 41.0649
C3H/HeJ both 43.6222 2.9865 49.5017 37.7427
C57BL/6J both 44.7444 2.9865 50.624 38.8649
CBA/J both 45.6111 2.9865 51.4906 39.7316
DBA/2J both 45.6111 2.9865 51.4906 39.7316
FVB/NJ both 53.9444 2.9865 59.824 48.0649




  GWAS USING LINEAR MIXED MODELS