Project measure / variable:   Bolivar2   act_shock_baseline

ID, description, units MPD:63901   act_shock_baseline   activity (beam breaks) during 2.5 min period of training on day 1   [n]  before shock  
Data set, strains Bolivar2   inbred   8 strains     sex: both     age: 9-20wks
Procedure fear conditioning test
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  STRAIN COMPARISON PLOT
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Bolivar2 - activity (beam breaks) during 2.5 min period of training on day 1 before shock



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means142.7   n 141.1   n
Median of the strain means143.2   n 133.2   n
SD of the strain means± 27.384 ± 33.526
Coefficient of variation (CV)0.1919 0.2376
Min–max range of strain means100.7   –   177.4   n 108.1   –   201.2   n
Mean sample size per strain18.0   mice 18.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 190.7756 190.7756 0.3153 0.5749
strain 7 221780.7978 31682.9711 52.3708 < 0.0001
sex:strain 7 14286.4689 2040.9241 3.3736 0.0018
Residuals 272 164552.9422 604.9741


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 120.8 32.035   18 7.5508 0.2651 54.4, 176.4 -0.8
129S1/SvImJ m 110.2 35.486   18 8.3641 0.322 51.6, 164.4 -0.92
A/J f 100.7 30.154   18 7.1073 0.2993 29.2, 146.4 -1.53
A/J m 115.1 27.042   18 6.3739 0.2349 71.2, 150.8 -0.78
BALB/cByJ f 177.4 20.905   18 4.9273 0.1178 130.0, 217.6 1.27
BALB/cByJ m 201.2 26.872   18 6.3339 0.1336 151.6, 234.0 1.79
C3H/HeJ f 126.4 14.579   18 3.4363 0.1153 102.0, 155.2 -0.6
C3H/HeJ m 119.7 16.401   18 3.8657 0.137 89.6, 150.4 -0.64
C57BL/6J f 163.0 13.699   18 3.229 0.0841 140.4, 189.2 0.74
C57BL/6J m 146.8 31.211   18 7.3565 0.2127 72.8, 207.6 0.17
CBA/J f 159.4 19.315   18 4.5527 0.1211 101.6, 182.4 0.61
CBA/J m 165.6 19.172   18 4.5188 0.1158 137.6, 196.4 0.73
DBA/2J f 126.9 31.685   18 7.4682 0.2497 66.0, 184.8 -0.58
DBA/2J m 108.1 19.608   18 4.6217 0.1814 58.8, 148.0 -0.98
FVB/NJ f 167.1 12.716   18 2.9971 0.0761 139.6, 186.4 0.89
FVB/NJ m 162.2 25.698   18 6.057 0.1585 122.4, 214.8 0.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 120.8222 5.7974 132.2357 109.4088
129S1/SvImJ m 110.2 5.7974 121.6134 98.7866
A/J f 100.7333 5.7974 112.1468 89.3199
A/J m 115.1111 5.7974 126.5246 103.6977
BALB/cByJ f 177.4444 5.7974 188.8579 166.031
BALB/cByJ m 201.2 5.7974 212.6134 189.7866
C3H/HeJ f 126.4222 5.7974 137.8357 115.0088
C3H/HeJ m 119.7111 5.7974 131.1246 108.2977
C57BL/6J f 162.9778 5.7974 174.3912 151.5643
C57BL/6J m 146.7556 5.7974 158.169 135.3421
CBA/J f 159.4444 5.7974 170.8579 148.031
CBA/J m 165.6 5.7974 177.0134 154.1866
DBA/2J f 126.8889 5.7974 138.3023 115.4754
DBA/2J m 108.0667 5.7974 119.4801 96.6532
FVB/NJ f 167.0889 5.7974 178.5023 155.6754
FVB/NJ m 162.1556 5.7974 173.569 150.7421


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 115.5111 4.0994 123.5816 107.4406
A/J both 107.9222 4.0994 115.9927 99.8517
BALB/cByJ both 189.3222 4.0994 197.3927 181.2517
C3H/HeJ both 123.0667 4.0994 131.1372 114.9961
C57BL/6J both 154.8667 4.0994 162.9372 146.7961
CBA/J both 162.5222 4.0994 170.5927 154.4517
DBA/2J both 117.4778 4.0994 125.5483 109.4073
FVB/NJ both 164.6222 4.0994 172.6927 156.5517




  GWAS USING LINEAR MIXED MODELS