Phenotype measure:   Lesage1   CD4_pos_CD8_neg_of_Tcells

ID, description, units MPD:63516   CD4_pos_CD8_neg_of_Tcells   percentage of splenic T cells that are CD4+ CD8-   [%]
Data set, strains Lesage1   CC w/par   65 strains     sex: both     age: 5-8wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Lesage1 - percentage of splenic T cells that are CD4+ CD8-



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested46 strains65 strains
Mean of the strain means49.677   % 47.302   %
Median of the strain means50.76   % 50.65   %
SD of the strain means± 11.495 ± 13.669
Coefficient of variation (CV)0.2314 0.289
Min–max range of strain means24.2   –   72.35   % 17.467   –   73.5   %
Mean sample size per strain2.2   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.5323 1.5323 0.098 0.756
strain 12 9082.0429 756.8369 48.4096 < 0.0001
sex:strain 12 300.0879 25.0073 1.5995 0.1357
Residuals 36 562.8247 15.634


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 49.6 3.5355   2   2.5 0.0713 47.1, 52.1 -0.01
129S1/SvImJ m 51.05 4.0305   2   2.85 0.079 48.2, 53.9 0.27
A/J f 52.55 0.21213   2   0.15 0.004 52.4, 52.7 0.25
A/J m 55.55 4.879   2   3.45 0.0878 52.1, 59.0 0.6
C57BL/6J f 44.075 9.7284   4 4.8642 0.2207 36.7, 58.4 -0.49
C57BL/6J m 58.1 0.0   1   0.0 0.0 58.1, 58.1 0.79
CAST/EiJ f 61.2 6.7882   2   4.8 0.1109 56.4, 66.0 1.0
CAST/EiJ m 62.8 9.8995   2   7.0 0.1576 55.8, 69.8 1.13
CC008/Geni m 66.17 0.90738   3 0.52387 0.0137 65.5, 67.2 1.38
CC010/Geni f 47.5 0.28284   2   0.2 0.006 47.3, 47.7 -0.19
CC010/Geni m 50.3 0.0   1   0.0 0.0 50.3, 50.3 0.22
CC012/Geni f 38.85 0.77782   2   0.55 0.02 38.3, 39.4 -0.94
CC012/Geni m 27.9 2.8   3 1.6166 0.1004 24.7, 29.9 -1.42
CC013/Geni m 27.7 3.8743   3 2.2368 0.1399 23.3, 30.6 -1.43
CC016/Geni m 21.067 0.9609   3 0.55478 0.0456 20.2, 22.1 -1.92
CC020/Geni f 65.4 0.0   1   0.0 0.0 65.4, 65.4 1.37
CC020/Geni m 60.7 0.56569   2   0.4 0.0093 60.3, 61.1 0.98
CC023/Geni m 47.6 1.852   3 1.0693 0.0389 45.5, 49.0 0.02
CC024/Geni f 32.9 0.14142   2   0.1 0.0043 32.8, 33.0 -1.46
CC024/Geni m 45.4 0.0   1   0.0 0.0 45.4, 45.4 -0.14
CC025/Geni f 51.37 2.6633   3 1.5377 0.0518 49.1, 54.3 0.15
CC026/Geni m 30.0 2.571   3 1.4844 0.0857 28.0, 32.9 -1.27
CC027/Geni f 24.2 0.0   1   0.0 0.0 24.2, 24.2 -2.22
CC027/Geni m 24.75 2.4749   2   1.75 0.1 23.0, 26.5 -1.65
CC030/Geni f 48.7 9.1924   2   6.5 0.1888 42.2, 55.2 -0.08
CC031/Geni f 34.1 0.0   1   0.0 0.0 34.1, 34.1 -1.36
CC031/Geni m 30.4 3.1113   2   2.2 0.1023 28.2, 32.6 -1.24
CC032/Geni m 62.2 3.079   3 1.7776 0.0495 59.6, 65.6 1.09
CC033/Geni f 38.367 1.9502   3 1.126 0.0508 37.0, 40.6 -0.98
CC038/Geni f 36.3 4.9497   2   3.5 0.1364 32.8, 39.8 -1.16
CC038/Geni m 43.3 0.0   1   0.0 0.0 43.3, 43.3 -0.29
CC042/Geni m 57.27 2.7465   3 1.5857 0.048 54.2, 59.5 0.73
CC043/Geni m 64.3 1.2   3 0.69282 0.0187 63.1, 65.5 1.24
CC056/Geni f 55.1 0.0   1   0.0 0.0 55.1, 55.1 0.47
CC056/Geni m 55.75 0.35355   2   0.25 0.0063 55.5, 56.0 0.62
CC061/Geni m 32.867 4.0501   3 2.3383 0.1232 28.4, 36.3 -1.06
CIV2_FE f 57.93 2.1385   3 1.2347 0.0369 56.6, 60.4 0.72
DET3_GA m 61.1 0.91652   3 0.52915 0.015 60.3, 62.1 1.01
DONNELL_HA f 57.05 0.77782   2   0.55 0.0136 56.5, 57.6 0.64
DONNELL_HA m 58.17 0.76376   3 0.44096 0.0131 57.5, 59.0 0.8
FIV_AC m 35.4 5.9369   4 2.9684 0.1677 29.6, 41.1 -0.87
FUF_HE f 62.37 1.2014   3 0.69362 0.0193 61.2, 63.6 1.1
GALASUPREME_CE m 38.133 2.669   3 1.5409 0.07 35.3, 40.6 -0.67
GIT_GC f 56.0 0.0   1   0.0 0.0 56.0, 56.0 0.55
GIT_GC m 58.7 3.2527   2   2.3 0.0554 56.4, 61.0 0.83
HAX2_EF f 34.767 0.75719   3 0.43716 0.0218 33.9, 35.3 -1.3
HAZ_FE f 56.8 0.0   1   0.0 0.0 56.8, 56.8 0.62
HAZ_FE m 64.9 0.28284   2   0.2 0.0044 64.7, 65.1 1.29
HIP_GA f 43.9 0.0   1   0.0 0.0 43.9, 43.9 -0.5
HIP_GA m 44.4 0.98995   2   0.7 0.0223 43.7, 45.1 -0.21
HOE_GC f 47.8 0.0   1   0.0 0.0 47.8, 47.8 -0.16
HOE_GC m 44.8 0.42426   2   0.3 0.0095 44.5, 45.1 -0.18
JUD_EF m 48.175 7.3323   4 3.6661 0.1522 40.4, 55.7 0.06
KAV_AF f 71.45 2.192   2   1.55 0.0307 69.9, 73.0 1.89
KAV_AF m 73.5 0.0   1   0.0 0.0 73.5, 73.5 1.92
LAM_DC f 33.9 0.0   1   0.0 0.0 33.9, 33.9 -1.37
LAM_DC m 34.6 0.0   1   0.0 0.0 34.6, 34.6 -0.93
LAT_HD f 36.52 2.8726   5 1.2847 0.0787 32.6, 39.4 -1.14
LAT_HD m 40.5 3.677   2   2.6 0.0908 37.9, 43.1 -0.5
LAX_FC m 50.65 0.91924   2   0.65 0.0181 50.0, 51.3 0.24
LEL_FH m 54.05 2.3335   2   1.65 0.0432 52.4, 55.7 0.49
LIP_BG f 53.95 4.0542   4 2.0271 0.0751 49.8, 59.2 0.37
LIP_BG m 57.3 0.0   1   0.0 0.0 57.3, 57.3 0.73
LIV_DA f 48.5 0.0   1   0.0 0.0 48.5, 48.5 -0.1
LIV_DA m 50.1 3.3941   2   2.4 0.0677 47.7, 52.5 0.2
LOD_AE f 65.77 2.2679   3 1.3094 0.0345 63.2, 67.5 1.4
LOM_BG m 53.2 1.7776   3 1.0263 0.0334 51.8, 55.2 0.43
LOT_FC f 52.73 0.98658   3 0.5696 0.0187 51.6, 53.4 0.27
LOT_FC m 58.95 9.8288   2   6.95 0.1667 52.0, 65.9 0.85
LOX_GF m 25.667 1.222   3 0.70553 0.0476 24.6, 27.0 -1.58
LUF_AD m 51.66 19.826   5 8.8665 0.3838 29.5, 67.3 0.32
LUG_EH m 30.5 1.7059   3 0.98489 0.0559 29.1, 32.4 -1.23
LUS_AH f 32.4 1.5716   3 0.90738 0.0485 31.3, 34.2 -1.5
LUV_DG m 29.675 6.5271   4 3.2635 0.22 23.8, 37.3 -1.29
LUZ_FH f 72.35 4.3134   2   3.05 0.0596 69.3, 75.4 1.97
LUZ_FH m 70.3 0.0   1   0.0 0.0 70.3, 70.3 1.68
MERCURI_HF m 17.467 2.635   3 1.5213 0.1509 15.3, 20.4 -2.18
NOD/ShiLtJ f 58.15 2.3335   2   1.65 0.0401 56.5, 59.8 0.74
NOD/ShiLtJ m 55.8 0.70711   2   0.5 0.0127 55.3, 56.3 0.62
NZO/HlLtJ f 62.85 3.0406   2   2.15 0.0484 60.7, 65.0 1.15
NZO/HlLtJ m 62.7 1.8385   2   1.3 0.0293 61.4, 64.0 1.13
PAT_CD m 27.7 0.55678   3 0.32146 0.0201 27.2, 28.3 -1.43
PEF_EC f 25.467 5.0767   3 2.9311 0.1993 19.8, 29.6 -2.11
PEF_EC m 20.5 4.7032   3 2.7154 0.2294 15.7, 25.1 -1.96
POH_DC f 43.7 5.6321   3 3.2517 0.1289 37.3, 47.9 -0.52
PWK/PhJ f 50.15 1.7678   2   1.25 0.0352 48.9, 51.4 0.04
PWK/PhJ m 54.1 4.1012   2   2.9 0.0758 51.2, 57.0 0.5
SEH_AH f 54.8 0.0   1   0.0 0.0 54.8, 54.8 0.45
SEH_AH m 51.0 0.0   1   0.0 0.0 51.0, 51.0 0.27
STUCKY_HF f 52.03 7.9576   3 4.5943 0.1529 46.9, 61.2 0.2
STUCKY_HF m 58.7 0.0   1   0.0 0.0 58.7, 58.7 0.83
VIT_ED f 62.77 0.56862   3 0.3283 0.0091 62.3, 63.4 1.14
VUX2_HF m 62.27 2.5541   3 1.4746 0.041 59.8, 64.9 1.09
WAD f 57.97 1.6442   3 0.94927 0.0284 56.1, 59.2 0.72
WSB/EiJ f 58.45 5.4447   2   3.85 0.0932 54.6, 62.3 0.76
WSB/EiJ m 57.3 3.677   2   2.6 0.0642 54.7, 59.9 0.73
XAD8_BG f 49.8 0.0   1   0.0 0.0 49.8, 49.8 0.01
XAD8_BG m 50.07 2.1572   3 1.2454 0.0431 47.6, 51.6 0.2
XAH3_GH m 52.67 3.7634   3 2.1728 0.0715 49.7, 56.9 0.39
XAS4_AF m 37.867 1.0786   3 0.62272 0.0285 37.1, 39.1 -0.69
XAV_AH m 46.667 1.7926   3 1.0349 0.0384 44.6, 47.8 -0.05
XAW2_CD m 39.3 0.56569   2   0.4 0.0144 38.9, 39.7 -0.59
XEB2_AG f 48.3 2.4759   3 1.4295 0.0513 45.5, 50.2 -0.12
XEB2_AG m 45.267 2.5775   3 1.4881 0.0569 42.5, 47.6 -0.15
XEB_AF f 52.5 0.84853   2   0.6 0.0162 51.9, 53.1 0.25
XEB_AF m 54.5 0.0   1   0.0 0.0 54.5, 54.5 0.53
XEQ_EH m 27.933 0.98658   3 0.5696 0.0353 26.8, 28.6 -1.42
XXEN2_DC m 56.2 0.75498   3 0.43589 0.0134 55.4, 56.9 0.65
XXEN3_DC f 43.8 0.0   1   0.0 0.0 43.8, 43.8 -0.51
XXEN3_DC m 52.2 0.0   1   0.0 0.0 52.2, 52.2 0.36
YOX_DE m 34.833 10.515   3 6.0711 0.3019 22.7, 41.3 -0.91


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 49.6 2.7959 55.2703 43.9297
129S1/SvImJ m 51.05 2.7959 56.7203 45.3797
A/J f 52.55 2.7959 58.2203 46.8797
A/J m 55.55 2.7959 61.2203 49.8797
CAST/EiJ f 61.2 2.7959 66.8703 55.5297
CAST/EiJ m 62.8 2.7959 68.4703 57.1297
CC012/Geni f 38.85 2.7959 44.5203 33.1797
CC012/Geni m 27.9 2.2828 32.5298 23.2702
DONNELL_HA f 57.05 2.7959 62.7203 51.3797
DONNELL_HA m 58.1667 2.2828 62.7965 53.5369
LAT_HD f 36.52 1.7683 40.1062 32.9338
LAT_HD m 40.5 2.7959 46.1703 34.8297
LOT_FC f 52.7333 2.2828 57.3631 48.1035
LOT_FC m 58.95 2.7959 64.6203 53.2797
NOD/ShiLtJ f 58.15 2.7959 63.8203 52.4797
NOD/ShiLtJ m 55.8 2.7959 61.4703 50.1297
NZO/HlLtJ f 62.85 2.7959 68.5203 57.1797
NZO/HlLtJ m 62.7 2.7959 68.3703 57.0297
PEF_EC f 25.4667 2.2828 30.0965 20.8369
PEF_EC m 20.5 2.2828 25.1298 15.8702
PWK/PhJ f 50.15 2.7959 55.8203 44.4797
PWK/PhJ m 54.1 2.7959 59.7703 48.4297
WSB/EiJ f 58.45 2.7959 64.1203 52.7797
WSB/EiJ m 57.3 2.7959 62.9703 51.6297
XEB2_AG f 48.3 2.2828 52.9298 43.6702
XEB2_AG m 45.2667 2.2828 49.8965 40.6369


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 50.325 1.977 54.3345 46.3155
A/J both 54.05 1.977 58.0595 50.0405
CAST/EiJ both 62.0 1.977 66.0095 57.9905
CC012/Geni both 33.375 1.8047 37.0352 29.7148
DONNELL_HA both 57.6083 1.8047 61.2685 53.9482
LAT_HD both 38.51 1.6541 41.8646 35.1554
LOT_FC both 55.8417 1.8047 59.5018 52.1815
NOD/ShiLtJ both 56.975 1.977 60.9845 52.9655
NZO/HlLtJ both 62.775 1.977 66.7845 58.7655
PEF_EC both 22.9833 1.6142 26.2571 19.7096
PWK/PhJ both 52.125 1.977 56.1345 48.1155
WSB/EiJ both 57.875 1.977 61.8845 53.8655
XEB2_AG both 46.7833 1.6142 50.0571 43.5096




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA