Project measure / variable:   Lesage1   CD4_pos_CD8_neg_of_NKT

ID, description, units MPD:63511   CD4_pos_CD8_neg_of_NKT   percentage of splenic NK T cells that are CD4+ CD8-   [%]  
Data set, strains Lesage1   CC w/par   76 strains     sex: both     age: 5-8wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Lesage1 - percentage of splenic NK T cells that are CD4+ CD8-



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested46 strains65 strains
Mean of the strain means69.74   % 66.56   %
Median of the strain means74.09   % 70.33   %
SD of the strain means± 15.801 ± 16.73
Coefficient of variation (CV)0.2266 0.2513
Min–max range of strain means21.8   –   92.6   % 14.167   –   91.8   %
Mean sample size per strain2.2   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 260.5749 260.5749 36.1966 < 0.0001
strain 12 11900.293 991.6911 137.7563 < 0.0001
sex:strain 12 238.6042 19.8837 2.7621 0.0091
Residuals 36 259.1597 7.1989


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 84.75 0.21213   2   0.15 0.0025 84.6, 84.9 0.95
129S1/SvImJ m 82.85 0.35355   2   0.25 0.0043 82.6, 83.1 0.97
A/J f 92.6 0.28284   2   0.2 0.0031 92.4, 92.8 1.45
A/J m 91.8 0.98995   2   0.7 0.0108 91.1, 92.5 1.51
C57BL/6J f 81.58 2.9792   4 1.4896 0.0365 77.4, 84.3 0.75
C57BL/6J m 78.7 0.0   1   0.0 0.0 78.7, 78.7 0.73
CAST/EiJ f 72.25 0.49497   2   0.35 0.0069 71.9, 72.6 0.16
CAST/EiJ m 69.35 0.91924   2   0.65 0.0133 68.7, 70.0 0.17
CC008/Geni m 55.2 17.367   3 10.027 0.3146 42.1, 74.9 -0.68
CC010/Geni f 82.6 1.2728   2   0.9 0.0154 81.7, 83.5 0.81
CC010/Geni m 80.3 0.0   1   0.0 0.0 80.3, 80.3 0.82
CC012/Geni f 79.05 1.3435   2   0.95 0.017 78.1, 80.0 0.59
CC012/Geni m 74.9 2.816   3 1.6258 0.0376 72.8, 78.1 0.5
CC013/Geni m 88.0 0.8544   3 0.49329 0.0097 87.1, 88.8 1.28
CC016/Geni m 49.633 1.9553   3 1.1289 0.0394 47.6, 51.5 -1.01
CC020/Geni f 72.4 0.0   1   0.0 0.0 72.4, 72.4 0.17
CC020/Geni m 70.85 0.6364   2   0.45 0.009 70.4, 71.3 0.26
CC023/Geni m 66.4 3.0643   3 1.7692 0.0461 62.9, 68.6 -0.01
CC024/Geni f 58.65 1.0607   2   0.75 0.0181 57.9, 59.4 -0.7
CC024/Geni m 49.9 0.0   1   0.0 0.0 49.9, 49.9 -1.0
CC025/Geni f 71.43 1.365   3 0.78811 0.0191 70.2, 72.9 0.11
CC026/Geni m 69.6 0.65574   3 0.37859 0.0094 69.0, 70.3 0.18
CC027/Geni f 58.6 0.0   1   0.0 0.0 58.6, 58.6 -0.71
CC027/Geni m 54.45 1.3435   2   0.95 0.0247 53.5, 55.4 -0.72
CC030/Geni f 68.9 1.2728   2   0.9 0.0185 68.0, 69.8 -0.05
CC031/Geni f 52.1 0.0   1   0.0 0.0 52.1, 52.1 -1.12
CC031/Geni m 47.6 1.4142   2   1.0 0.0297 46.6, 48.6 -1.13
CC032/Geni m 42.267 2.6502   3 1.5301 0.0627 40.4, 45.3 -1.45
CC033/Geni f 42.367 4.2336   3 2.4443 0.0999 37.5, 45.2 -1.73
CC038/Geni f 60.8 3.677   2   2.6 0.0605 58.2, 63.4 -0.57
CC038/Geni m 70.6 0.0   1   0.0 0.0 70.6, 70.6 0.24
CC042/Geni m 14.167 0.95044   3 0.54874 0.0671 13.2, 15.1 -3.13
CC043/Geni m 86.73 3.296   3 1.9029 0.038 83.8, 90.3 1.21
CC056/Geni f 65.0 0.0   1   0.0 0.0 65.0, 65.0 -0.3
CC056/Geni m 67.75 1.3435   2   0.95 0.0198 66.8, 68.7 0.07
CC061/Geni m 55.1 1.044   3 0.60277 0.0189 54.4, 56.3 -0.69
CIV2_FE f 84.1 1.1269   3 0.65064 0.0134 82.8, 84.8 0.91
DET3_GA m 70.33 0.80829   3 0.46667 0.0115 69.4, 70.8 0.23
DONNELL_HA f 49.75 3.3234   2   2.35 0.0668 47.4, 52.1 -1.27
DONNELL_HA m 49.333 5.9366   3 3.4275 0.1203 42.9, 54.6 -1.03
FIV_AC m 50.83 7.2353   4 3.6176 0.1424 45.8, 61.3 -0.94
FUF_HE f 86.6 1.2767   3 0.73711 0.0147 85.2, 87.7 1.07
GALASUPREME_CE m 68.7 1.9519   3 1.1269 0.0284 66.7, 70.6 0.13
GIT_GC f 48.5 0.0   1   0.0 0.0 48.5, 48.5 -1.34
GIT_GC m 50.75 0.07071   2   0.05 0.0014 50.7, 50.8 -0.95
HAX2_EF f 83.83 0.90738   3 0.52387 0.0108 83.0, 84.8 0.89
HAZ_FE f 64.4 0.0   1   0.0 0.0 64.4, 64.4 -0.34
HAZ_FE m 70.75 6.8589   2   4.85 0.0969 65.9, 75.6 0.25
HIP_GA f 80.2 0.0   1   0.0 0.0 80.2, 80.2 0.66
HIP_GA m 75.65 0.49497   2   0.35 0.0065 75.3, 76.0 0.54
HOE_GC f 69.5 0.0   1   0.0 0.0 69.5, 69.5 -0.02
HOE_GC m 62.75 0.91924   2   0.65 0.0146 62.1, 63.4 -0.23
JUD_EF m 81.12 1.0966   4 0.54829 0.0135 79.5, 81.9 0.87
KAV_AF f 89.9 1.4142   2   1.0 0.0157 88.9, 90.9 1.28
KAV_AF m 88.7 0.0   1   0.0 0.0 88.7, 88.7 1.32
LAM_DC f 56.1 0.0   1   0.0 0.0 56.1, 56.1 -0.86
LAM_DC m 59.2 0.0   1   0.0 0.0 59.2, 59.2 -0.44
LAT_HD f 87.18 2.1406   5 0.95729 0.0246 84.4, 90.3 1.1
LAT_HD m 78.6 0.70711   2   0.5 0.009 78.1, 79.1 0.72
LAX_FC m 79.55 4.4548   2   3.15 0.056 76.4, 82.7 0.78
LEL_FH m 72.7 0.28284   2   0.2 0.0039 72.5, 72.9 0.37
LIP_BG f 74.38 2.5025   4 1.2512 0.0336 71.3, 77.4 0.29
LIP_BG m 70.9 0.0   1   0.0 0.0 70.9, 70.9 0.26
LIV_DA f 73.8 0.0   1   0.0 0.0 73.8, 73.8 0.26
LIV_DA m 71.2 2.5456   2   1.8 0.0358 69.4, 73.0 0.28
LOD_AE f 80.3 1.51   3 0.87178 0.0188 78.9, 81.9 0.67
LOM_BG m 24.367 5.5949   3 3.2302 0.2296 18.0, 28.5 -2.52
LOT_FC f 79.67 3.5726   3 2.0626 0.0448 75.6, 82.3 0.63
LOT_FC m 79.3 6.5054   2   4.6 0.082 74.7, 83.9 0.76
LOX_GF m 81.3 1.5395   3 0.88882 0.0189 80.0, 83.0 0.88
LUF_AD m 70.8 10.642   5 4.7594 0.1503 55.7, 79.5 0.25
LUG_EH m 55.37 2.3502   3 1.3569 0.0424 53.0, 57.7 -0.67
LUS_AH f 86.1 3.0199   3 1.7436 0.0351 82.9, 88.9 1.04
LUV_DG m 79.05 6.0169   4 3.0085 0.0761 74.0, 86.3 0.75
LUZ_FH f 82.75 1.4849   2   1.05 0.0179 81.7, 83.8 0.82
LUZ_FH m 84.0 0.0   1   0.0 0.0 84.0, 84.0 1.04
MERCURI_HF m 54.47 0.92916   3 0.53645 0.0171 53.7, 55.5 -0.72
NOD/ShiLtJ f 76.6 2.2627   2   1.6 0.0295 75.0, 78.2 0.43
NOD/ShiLtJ m 77.7 0.98995   2   0.7 0.0127 77.0, 78.4 0.67
NZO/HlLtJ f 67.8 1.2728   2   0.9 0.0188 66.9, 68.7 -0.12
NZO/HlLtJ m 63.75 4.7376   2   3.35 0.0743 60.4, 67.1 -0.17
PAT_CD m 69.4 1.562   3 0.90185 0.0225 67.6, 70.4 0.17
PEF_EC f 75.37 1.7954   3 1.0366 0.0238 74.0, 77.4 0.36
PEF_EC m 65.83 1.3204   3 0.76231 0.0201 64.4, 67.0 -0.04
POH_DC f 78.4 1.3077   3 0.75498 0.0167 77.5, 79.9 0.55
PWK/PhJ f 35.9 1.5556   2   1.1 0.0433 34.8, 37.0 -2.14
PWK/PhJ m 37.95 2.4749   2   1.75 0.0652 36.2, 39.7 -1.71
SEH_AH f 41.5 0.0   1   0.0 0.0 41.5, 41.5 -1.79
SEH_AH m 37.8 0.0   1   0.0 0.0 37.8, 37.8 -1.72
STUCKY_HF f 83.07 2.558   3 1.4769 0.0308 80.4, 85.5 0.84
STUCKY_HF m 79.8 0.0   1   0.0 0.0 79.8, 79.8 0.79
VIT_ED f 48.167 6.0682   3 3.5035 0.126 41.2, 52.3 -1.37
VUX2_HF m 77.33 0.80208   3 0.46308 0.0104 76.5, 78.1 0.64
WAD f 59.33 1.2583   3 0.72648 0.0212 58.0, 60.5 -0.66
WSB/EiJ f 77.25 2.4749   2   1.75 0.032 75.5, 79.0 0.48
WSB/EiJ m 80.6 0.70711   2   0.5 0.0088 80.1, 81.1 0.84
XAD8_BG f 21.8 0.0   1   0.0 0.0 21.8, 21.8 -3.03
XAD8_BG m 19.567 1.7388   3 1.0039 0.0889 17.6, 20.9 -2.81
XAH3_GH m 66.33 2.3587   3 1.3618 0.0356 64.1, 68.8 -0.01
XAS4_AF m 87.4 0.17321   3 0.1 0.002 87.3, 87.6 1.25
XAV_AH m 86.03 1.4503   3 0.83732 0.0169 84.6, 87.5 1.16
XAW2_CD m 53.55 10.253   2   7.25 0.1915 46.3, 60.8 -0.78
XEB2_AG f 81.2 2.4021   3 1.3868 0.0296 78.5, 83.1 0.73
XEB2_AG m 82.8 1.4422   3 0.83267 0.0174 81.2, 84.0 0.97
XEB_AF f 64.95 1.3435   2   0.95 0.0207 64.0, 65.9 -0.3
XEB_AF m 66.3 0.0   1   0.0 0.0 66.3, 66.3 -0.02
XEQ_EH m 68.43 2.1362   3 1.2333 0.0312 67.2, 70.9 0.11
XXEN2_DC m 72.93 2.1385   3 1.2347 0.0293 70.6, 74.8 0.38
XXEN3_DC f 76.7 0.0   1   0.0 0.0 76.7, 76.7 0.44
XXEN3_DC m 79.8 0.0   1   0.0 0.0 79.8, 79.8 0.79
YOX_DE m 57.33 2.6502   3 1.5301 0.0462 55.2, 60.3 -0.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 84.75 1.8972 88.5977 80.9023
129S1/SvImJ m 82.85 1.8972 86.6977 79.0023
A/J f 92.6 1.8972 96.4477 88.7523
A/J m 91.8 1.8972 95.6477 87.9523
CAST/EiJ f 72.25 1.8972 76.0977 68.4023
CAST/EiJ m 69.35 1.8972 73.1977 65.5023
CC012/Geni f 79.05 1.8972 82.8977 75.2023
CC012/Geni m 74.9 1.5491 78.0417 71.7583
DONNELL_HA f 49.75 1.8972 53.5977 45.9023
DONNELL_HA m 49.3333 1.5491 52.475 46.1917
LAT_HD f 87.18 1.1999 89.6135 84.7465
LAT_HD m 78.6 1.8972 82.4477 74.7523
LOT_FC f 79.6667 1.5491 82.8083 76.525
LOT_FC m 79.3 1.8972 83.1477 75.4523
NOD/ShiLtJ f 76.6 1.8972 80.4477 72.7523
NOD/ShiLtJ m 77.7 1.8972 81.5477 73.8523
NZO/HlLtJ f 67.8 1.8972 71.6477 63.9523
NZO/HlLtJ m 63.75 1.8972 67.5977 59.9023
PEF_EC f 75.3667 1.5491 78.5083 72.225
PEF_EC m 65.8333 1.5491 68.975 62.6917
PWK/PhJ f 35.9 1.8972 39.7477 32.0523
PWK/PhJ m 37.95 1.8972 41.7977 34.1023
WSB/EiJ f 77.25 1.8972 81.0977 73.4023
WSB/EiJ m 80.6 1.8972 84.4477 76.7523
XEB2_AG f 81.2 1.5491 84.3417 78.0583
XEB2_AG m 82.8 1.5491 85.9417 79.6583


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 83.8 1.3415 86.5208 81.0792
A/J both 92.2 1.3415 94.9208 89.4792
CAST/EiJ both 70.8 1.3415 73.5208 68.0792
CC012/Geni both 76.975 1.2246 79.4587 74.4913
DONNELL_HA both 49.5417 1.2246 52.0254 47.058
LAT_HD both 82.89 1.1224 85.1664 80.6136
LOT_FC both 79.4833 1.2246 81.967 76.9996
NOD/ShiLtJ both 77.15 1.3415 79.8708 74.4292
NZO/HlLtJ both 65.775 1.3415 68.4958 63.0542
PEF_EC both 70.6 1.0954 72.8215 68.3785
PWK/PhJ both 36.925 1.3415 39.6458 34.2042
WSB/EiJ both 78.925 1.3415 81.6458 76.2042
XEB2_AG both 82.0 1.0954 84.2215 79.7785




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA