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Project measure / variable:   Lesage1   NK_cells_of_CD3_neg

ID, description, units MPD:63502   NK_cells_of_CD3_neg   percentage of splenic CD3- lymphocytes that are NK cells (CD49+ CD19-)   [%]  
Data set, strains Lesage1   CC w/par   76 strains     sex: both     age: 5-8wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Lesage1 - percentage of splenic CD3- lymphocytes that are NK cells (CD49+ CD19-)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested47 strains64 strains
Mean of the strain means3.1566   % 3.4809   %
Median of the strain means2.29   % 2.9975   %
SD of the strain means± 2.455 ± 2.2116
Coefficient of variation (CV)0.7777 0.6354
Min–max range of strain means0.69   –   15.3   % 1.05   –   11.0   %
Mean sample size per strain2.3   mice 2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1288 0.1288 0.5483 0.4638
strain 11 162.3788 14.7617 62.8333 < 0.0001
sex:strain 11 2.019 0.1835 0.7813 0.6563
Residuals 36 8.4576 0.2349


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.29 0.38184   2   0.27 0.1667 2.02, 2.56 -0.35
129S1/SvImJ m 2.02 0.04243   2   0.03 0.021 1.99, 2.05 -0.66
A/J f 1.525 0.10607   2   0.075 0.0696 1.45, 1.6 -0.66
A/J m 1.45 0.01414   2   0.01 0.0098 1.44, 1.46 -0.92
C57BL/6J f 2.935 0.92378   4 0.46189 0.3147 1.9, 3.86 -0.09
C57BL/6J m 2.99 0.0   1   0.0 0.0 2.99, 2.99 -0.22
CAST/EiJ f 1.0155 0.26092   2   0.1845 0.2569 0.831, 1.2 -0.87
CAST/EiJ m 1.05 0.05657   2   0.04 0.0539 1.01, 1.09 -1.1
CC008/Geni m 2.475 0.03536   2   0.025 0.0143 2.45, 2.5 -0.45
CC010/Geni f 15.3 0.42426   2   0.3 0.0277 15.0, 15.6 4.95
CC010/Geni m 11.0 0.0   1   0.0 0.0 11.0, 11.0 3.4
CC012/Geni f 2.17 0.81357   3 0.46972 0.3749 1.24, 2.75 -0.4
CC012/Geni m 1.528 0.14446   5 0.06461 0.0945 1.39, 1.75 -0.88
CC013/Geni m 8.3067 1.9102   3 1.1029 0.23 6.38, 10.2 2.18
CC016/Geni m 9.9367 0.32868   3 0.18977 0.0331 9.66, 10.3 2.92
CC020/Geni f 1.65 0.0   1   0.0 0.0 1.65, 1.65 -0.61
CC020/Geni m 1.7 0.31113   2   0.22 0.183 1.48, 1.92 -0.81
CC023/Geni m 3.6933 0.51433   3 0.29695 0.1393 3.32, 4.28 0.1
CC024/Geni f 6.435 1.2657   2   0.895 0.1967 5.54, 7.33 1.34
CC024/Geni m 8.08 0.0   1   0.0 0.0 8.08, 8.08 2.08
CC025/Geni f 1.1897 0.24633   3 0.14222 0.2071 0.909, 1.37 -0.8
CC026/Geni m 5.4433 0.31786   3 0.18352 0.0584 5.08, 5.67 0.89
CC027/Geni f 3.68 0.0   1   0.0 0.0 3.68, 3.68 0.21
CC027/Geni m 4.61 1.9092   2   1.35 0.4141 3.26, 5.96 0.51
CC030/Geni f 0.9745 0.00636396   2   0.0045 0.0065 0.97, 0.979 -0.89
CC031/Geni f 6.76 0.0   1   0.0 0.0 6.76, 6.76 1.47
CC031/Geni m 6.84 0.2687   2   0.19 0.0393 6.65, 7.03 1.52
CC032/Geni m 3.5467 0.36529   3 0.2109 0.103 3.19, 3.92 0.03
CC033/Geni f 4.44 0.40951   3 0.23643 0.0922 4.0, 4.81 0.52
CC038/Geni f 1.415 0.06364   2   0.045 0.045 1.37, 1.46 -0.71
CC038/Geni m 1.69 0.0   1   0.0 0.0 1.69, 1.69 -0.81
CC042/Geni m 3.7067 0.29738   3 0.17169 0.0802 3.39, 3.98 0.1
CC043/Geni m 3.38 0.34511   3 0.19925 0.1021 3.04, 3.73 -0.05
CC056/Geni f 2.09 0.0   1   0.0 0.0 2.09, 2.09 -0.43
CC056/Geni m 2.19 0.22627   2   0.16 0.1033 2.03, 2.35 -0.58
CC061/Geni m 1.5667 0.1159   3 0.06692 0.074 1.46, 1.69 -0.87
CIV2_FE f 2.7067 0.88081   3 0.50854 0.3254 1.99, 3.69 -0.18
DET3_GA m 2.5867 0.43684   3 0.25221 0.1689 2.22, 3.07 -0.4
DONNELL_HA f 2.71 0.70711   2   0.5 0.2609 2.21, 3.21 -0.18
DONNELL_HA m 2.92 0.69397   3 0.40067 0.2377 2.32, 3.68 -0.25
FIV_AC m 3.49 0.24617   4 0.12309 0.0705 3.16, 3.73 0.0
FUF_HE f 0.69 0.11882   3 0.0686 0.1722 0.553, 0.765 -1.0
GALASUPREME_CE m 1.3333 0.15373   3 0.08876 0.1153 1.23, 1.51 -0.97
GIT_GC f 4.05 0.0   1   0.0 0.0 4.05, 4.05 0.36
GIT_GC m 4.365 0.62933   2   0.445 0.1442 3.92, 4.81 0.4
HAX2_EF f 2.1 0.1044   3 0.06028 0.0497 1.98, 2.17 -0.43
HAZ_FE f 3.83 0.0   1   0.0 0.0 3.83, 3.83 0.27
HAZ_FE m 2.65 1.0607   2   0.75 0.4002 1.9, 3.4 -0.38
HIP_GA f 1.25 0.0   1   0.0 0.0 1.25, 1.25 -0.78
HIP_GA m 1.34 0.15556   2   0.11 0.1161 1.23, 1.45 -0.97
HOE_GC f 1.25 0.0   1   0.0 0.0 1.25, 1.25 -0.78
HOE_GC m 1.835 0.27577   2   0.195 0.1503 1.64, 2.03 -0.74
JUD_EF m 3.6025 1.1355   4 0.56775 0.3152 2.88, 5.28 0.06
KAV_AF f 4.79 0.32527   2   0.23 0.0679 4.56, 5.02 0.67
KAV_AF m 5.2 0.0   1   0.0 0.0 5.2, 5.2 0.78
LAM_DC f 4.3 0.0   1   0.0 0.0 4.3, 4.3 0.47
LAM_DC m 4.955 0.44548   2   0.315 0.0899 4.64, 5.27 0.67
LAT_HD f 1.5098 0.6594   5 0.29489 0.4367 0.765, 2.41 -0.67
LAT_HD m 1.42 0.09899   2   0.07 0.0697 1.35, 1.49 -0.93
LAX_FC f 1.93 0.0   1   0.0 0.0 1.93, 1.93 -0.5
LAX_FC m 1.76 0.0   1   0.0 0.0 1.76, 1.76 -0.78
LEL_FH m 3.005 0.61518   2   0.435 0.2047 2.57, 3.44 -0.22
LIP_BG f 2.225 0.26901   4 0.13451 0.1209 1.84, 2.42 -0.38
LIP_BG m 2.98 0.0   1   0.0 0.0 2.98, 2.98 -0.23
LIV_DA f 2.23 0.0   1   0.0 0.0 2.23, 2.23 -0.38
LIV_DA m 2.625 0.36062   2   0.255 0.1374 2.37, 2.88 -0.39
LOD_AE f 4.0367 0.40772   3 0.2354 0.101 3.7, 4.49 0.36
LOM_BG m 3.3633 0.51868   3 0.29946 0.1542 3.02, 3.96 -0.05
LOT_FC f 1.7117 0.48375   6 0.19749 0.2826 1.19, 2.57 -0.59
LOX_GF m 7.0433 0.52539   3 0.30333 0.0746 6.65, 7.64 1.61
LUF_AD m 7.178 0.76398   5 0.34166 0.1064 6.24, 8.28 1.67
LUG_EH m 1.3833 0.0057735   3 0.00333333 0.0042 1.38, 1.39 -0.95
LUS_AH f 1.94 0.11533   3 0.06658 0.0594 1.85, 2.07 -0.5
LUV_DG m 3.845 0.48239   4 0.24119 0.1255 3.19, 4.34 0.16
LUZ_FH f 1.76 0.44189   4 0.22094 0.2511 1.31, 2.33 -0.57
LUZ_FH m 1.29 0.0   1   0.0 0.0 1.29, 1.29 -0.99
MERCURI_HF m 4.2467 0.27392   3 0.15815 0.0645 3.95, 4.49 0.35
NOD/ShiLtJ f 4.46 1.1172   2   0.79 0.2505 3.67, 5.25 0.53
NOD/ShiLtJ m 3.44 0.5374   2   0.38 0.1562 3.06, 3.82 -0.02
NZO/HlLtJ f 7.56 1.0182   2   0.72 0.1347 6.84, 8.28 1.79
NZO/HlLtJ m 8.02 0.21213   2   0.15 0.0265 7.87, 8.17 2.05
PAT_CD m 3.72 0.21633   3 0.1249 0.0582 3.54, 3.96 0.11
PEF_EC f 1.3867 0.17156   3 0.09905 0.1237 1.23, 1.57 -0.72
PEF_EC m 1.38 0.28513   3 0.16462 0.2066 1.1, 1.67 -0.95
POH_DC f 2.6633 0.20207   3 0.11667 0.0759 2.43, 2.78 -0.2
PWK/PhJ f 1.455 0.10607   2   0.075 0.0729 1.38, 1.53 -0.69
PWK/PhJ m 1.42 0.12728   2   0.09 0.0896 1.33, 1.51 -0.93
SEH_AH f 4.06 0.0   1   0.0 0.0 4.06, 4.06 0.37
SEH_AH m 3.915 0.71761   4 0.35881 0.1833 3.33, 4.93 0.2
STUCKY_HF f 1.3433 0.11846   3 0.06839 0.0882 1.27, 1.48 -0.74
STUCKY_HF m 1.27 0.0   1   0.0 0.0 1.27, 1.27 -1.0
VIT_ED f 2.04 0.34395   3 0.19858 0.1686 1.75, 2.42 -0.45
VUX2_HF m 2.58 1.6538   3 0.95479 0.641 1.31, 4.45 -0.41
WAD f 4.27 0.5889   3 0.34 0.1379 3.93, 4.95 0.45
WSB/EiJ f 2.37 0.45255   2   0.32 0.1909 2.05, 2.69 -0.32
WSB/EiJ m 1.9 0.11314   2   0.08 0.0595 1.82, 1.98 -0.71
XAD8_BG f 5.53 0.0   1   0.0 0.0 5.53, 5.53 0.97
XAD8_BG m 5.1967 0.15535   3 0.08969 0.0299 5.07, 5.37 0.78
XAH3_GH m 4.02 0.04583   3 0.02646 0.0114 3.97, 4.06 0.24
XAS4_AF m 4.6533 0.71178   3 0.41095 0.153 4.08, 5.45 0.53
XAV_AH m 1.5533 0.03786   3 0.02186 0.0244 1.51, 1.58 -0.87
XAW2_CD m 2.26 0.21213   2   0.15 0.0939 2.11, 2.41 -0.55
XEB2_AG f 3.2933 0.35233   3 0.20342 0.107 3.08, 3.7 0.06
XEB2_AG m 3.37 0.37027   3 0.21378 0.1099 3.06, 3.78 -0.05
XEB_AF f 3.15 0.32527   2   0.23 0.1033 2.92, 3.38 0.0
XEB_AF m 2.14 0.0   1   0.0 0.0 2.14, 2.14 -0.61
XEQ_EH m 1.0833 0.12897   3 0.07446 0.119 0.94, 1.19 -1.08
XXEN2_DC m 3.1133 0.64376   3 0.37168 0.2068 2.37, 3.49 -0.17
XXEN3_DC f 5.89 0.0   1   0.0 0.0 5.89, 5.89 1.11
XXEN3_DC m 2.83 0.0   1   0.0 0.0 2.83, 2.83 -0.29
YOX_DE m 3.29 0.69203   3 0.39954 0.2103 2.72, 4.06 -0.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.29 0.3427 2.9851 1.5949
129S1/SvImJ m 2.02 0.3427 2.7151 1.3249
A/J f 1.525 0.3427 2.2201 0.8299
A/J m 1.45 0.3427 2.1451 0.7549
CAST/EiJ f 1.0155 0.3427 1.7106 0.3204
CAST/EiJ m 1.05 0.3427 1.7451 0.3549
CC012/Geni f 2.17 0.2798 2.7375 1.6025
CC012/Geni m 1.528 0.2168 1.9676 1.0884
DONNELL_HA f 2.71 0.3427 3.4051 2.0149
DONNELL_HA m 2.92 0.2798 3.4875 2.3525
LAT_HD f 1.5098 0.2168 1.9494 1.0702
LAT_HD m 1.42 0.3427 2.1151 0.7249
NOD/ShiLtJ f 4.46 0.3427 5.1551 3.7649
NOD/ShiLtJ m 3.44 0.3427 4.1351 2.7449
NZO/HlLtJ f 7.56 0.3427 8.2551 6.8649
NZO/HlLtJ m 8.02 0.3427 8.7151 7.3249
PEF_EC f 1.3867 0.2798 1.9542 0.8191
PEF_EC m 1.38 0.2798 1.9475 0.8125
PWK/PhJ f 1.455 0.3427 2.1501 0.7599
PWK/PhJ m 1.42 0.3427 2.1151 0.7249
WSB/EiJ f 2.37 0.3427 3.0651 1.6749
WSB/EiJ m 1.9 0.3427 2.5951 1.2049
XEB2_AG f 3.2933 0.2798 3.8609 2.7258
XEB2_AG m 3.37 0.2798 3.9375 2.8025


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.155 0.2424 2.6465 1.6635
A/J both 1.4875 0.2424 1.979 0.996
CAST/EiJ both 1.0327 0.2424 1.5243 0.5412
CC012/Geni both 1.849 0.177 2.2079 1.4901
DONNELL_HA both 2.815 0.2212 3.2637 2.3663
LAT_HD both 1.4649 0.2028 1.8761 1.0537
NOD/ShiLtJ both 3.95 0.2424 4.4415 3.4585
NZO/HlLtJ both 7.79 0.2424 8.2815 7.2985
PEF_EC both 1.3833 0.1979 1.7846 0.982
PWK/PhJ both 1.4375 0.2424 1.929 0.946
WSB/EiJ both 2.135 0.2424 2.6265 1.6435
XEB2_AG both 3.3317 0.1979 3.733 2.9304




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA