Phenotype measure:   Lesage1   CD3_neg

ID, description, units MPD:63501   CD3_neg   percentage of splenic lymphocytes that are CD3-   [%]
Data set, strains Lesage1   CC w/par   64 strains     sex: both     age: 5-8wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Lesage1 - percentage of splenic lymphocytes that are CD3-



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested47 strains64 strains
Mean of the strain means72.38   % 75.57   %
Median of the strain means74.6   % 75.45   %
SD of the strain means± 10.351 ± 8.6439
Coefficient of variation (CV)0.143 0.1144
Min–max range of strain means43.6   –   88.43   % 40.9   –   90.95   %
Mean sample size per strain2.3   mice 2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 571.0335 571.0335 4.5415 0.04
strain 11 4722.828 429.348 3.4147 0.0026
sex:strain 11 1499.5454 136.3223 1.0842 0.4005
Residuals 36 4526.475 125.7354


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 48.7 31.254   2   22.1 0.6418 26.6, 70.8 -2.29
129S1/SvImJ m 77.55 14.354   2   10.15 0.1851 67.4, 87.7 0.23
A/J f 77.25 1.3435   2   0.95 0.0174 76.3, 78.2 0.47
A/J m 80.4 3.3941   2   2.4 0.0422 78.0, 82.8 0.56
C57BL/6J f 76.32 6.3015   4 3.1508 0.0826 70.5, 83.5 0.38
C57BL/6J m 74.4 0.0   1   0.0 0.0 74.4, 74.4 -0.13
CAST/EiJ f 60.65 40.234   2   28.45 0.6634 32.2, 89.1 -1.13
CAST/EiJ m 90.95 2.4749   2   1.75 0.0272 89.2, 92.7 1.78
CC008/Geni m 87.55 2.192   2   1.55 0.025 86.0, 89.1 1.39
CC010/Geni f 43.6 2.2627   2   1.6 0.0519 42.0, 45.2 -2.78
CC010/Geni m 40.9 0.0   1   0.0 0.0 40.9, 40.9 -4.01
CC012/Geni f 87.37 1.2858   3 0.74237 0.0147 85.9, 88.3 1.45
CC012/Geni m 88.32 0.93381   5 0.41761 0.0106 86.7, 89.1 1.48
CC013/Geni m 75.9 1.3229   3 0.76376 0.0174 74.9, 77.4 0.04
CC016/Geni m 74.93 0.95044   3 0.54874 0.0127 74.0, 75.9 -0.07
CC020/Geni f 66.1 0.0   1   0.0 0.0 66.1, 66.1 -0.61
CC020/Geni m 69.65 3.4648   2   2.45 0.0497 67.2, 72.1 -0.68
CC023/Geni m 83.03 1.9399   3 1.12 0.0234 80.8, 84.3 0.86
CC024/Geni f 78.3 1.6971   2   1.2 0.0217 77.1, 79.5 0.57
CC024/Geni m 82.0 0.0   1   0.0 0.0 82.0, 82.0 0.74
CC025/Geni f 69.3 0.5   3 0.28868 0.0072 68.8, 69.8 -0.3
CC026/Geni m 73.87 1.7616   3 1.0171 0.0238 72.8, 75.9 -0.2
CC027/Geni f 68.9 0.0   1   0.0 0.0 68.9, 68.9 -0.34
CC027/Geni m 63.7 2.4042   2   1.7 0.0377 62.0, 65.4 -1.37
CC030/Geni f 78.5 0.98995   2   0.7 0.0126 77.8, 79.2 0.59
CC031/Geni f 71.8 0.0   1   0.0 0.0 71.8, 71.8 -0.06
CC031/Geni m 71.95 2.0506   2   1.45 0.0285 70.5, 73.4 -0.42
CC032/Geni m 74.2 2.1656   3 1.2503 0.0292 72.9, 76.7 -0.16
CC033/Geni f 83.53 0.75719   3 0.43716 0.0091 83.0, 84.4 1.08
CC038/Geni f 84.05 0.49497   2   0.35 0.0059 83.7, 84.4 1.13
CC038/Geni m 84.8 0.0   1   0.0 0.0 84.8, 84.8 1.07
CC042/Geni m 85.23 0.90738   3 0.52387 0.0106 84.2, 85.9 1.12
CC043/Geni m 73.1 1.2166   3 0.70238 0.0166 72.3, 74.5 -0.29
CC056/Geni f 70.5 0.0   1   0.0 0.0 70.5, 70.5 -0.18
CC056/Geni m 74.05 1.7678   2   1.25 0.0239 72.8, 75.3 -0.18
CC061/Geni m 77.17 2.7025   3 1.5603 0.035 74.1, 79.2 0.19
CIV2_FE f 81.0 1.1   3 0.63509 0.0136 79.9, 82.1 0.83
DET3_GA m 75.43 1.7039   3 0.98376 0.0226 73.8, 77.2 -0.02
DONNELL_HA f 69.8 1.1314   2   0.8 0.0162 69.0, 70.6 -0.25
DONNELL_HA m 71.13 3.5921   3 2.0739 0.0505 67.0, 73.5 -0.51
FIV_AC m 59.33 6.4469   4 3.2234 0.1087 53.6, 65.3 -1.88
FUF_HE f 77.4 3.214   3 1.8556 0.0415 75.3, 81.1 0.48
GALASUPREME_CE m 80.47 2.3502   3 1.3569 0.0292 78.1, 82.8 0.57
GIT_GC f 74.6 0.0   1   0.0 0.0 74.6, 74.6 0.21
GIT_GC m 75.4 1.6971   2   1.2 0.0225 74.2, 76.6 -0.02
HAX2_EF f 77.93 0.11547   3 0.06667 0.0015 77.8, 78.0 0.54
HAZ_FE f 73.1 0.0   1   0.0 0.0 73.1, 73.1 0.07
HAZ_FE m 76.45 0.49497   2   0.35 0.0065 76.1, 76.8 0.1
HIP_GA f 66.7 0.0   1   0.0 0.0 66.7, 66.7 -0.55
HIP_GA m 67.85 0.21213   2   0.15 0.0031 67.7, 68.0 -0.89
HOE_GC f 76.0 0.0   1   0.0 0.0 76.0, 76.0 0.35
HOE_GC m 75.45 2.6163   2   1.85 0.0347 73.6, 77.3 -0.01
JUD_EF m 85.98 1.2148   4 0.60742 0.0141 84.3, 87.2 1.2
KAV_AF f 76.65 0.35355   2   0.25 0.0046 76.4, 76.9 0.41
KAV_AF m 75.3 0.0   1   0.0 0.0 75.3, 75.3 -0.03
LAM_DC f 73.1 0.0   1   0.0 0.0 73.1, 73.1 0.07
LAM_DC m 71.3 10.607   2   7.5 0.1488 63.8, 78.8 -0.49
LAT_HD f 71.34 7.6409   5 3.4171 0.1071 63.0, 79.5 -0.1
LAT_HD m 75.45 0.49497   2   0.35 0.0066 75.1, 75.8 -0.01
LAX_FC f 87.4 0.0   1   0.0 0.0 87.4, 87.4 1.45
LAX_FC m 87.6 0.0   1   0.0 0.0 87.6, 87.6 1.39
LEL_FH m 74.5 2.8284   2   2.0 0.038 72.5, 76.5 -0.12
LIP_BG f 60.83 2.5851   4 1.2925 0.0425 57.9, 63.0 -1.12
LIP_BG m 58.4 0.0   1   0.0 0.0 58.4, 58.4 -1.99
LIV_DA f 63.6 0.0   1   0.0 0.0 63.6, 63.6 -0.85
LIV_DA m 70.1 1.6971   2   1.2 0.0242 68.9, 71.3 -0.63
LOD_AE f 67.7 1.0817   3 0.6245 0.016 66.8, 68.9 -0.45
LOM_BG m 65.1 2.1   3 1.2124 0.0323 63.0, 67.2 -1.21
LOT_FC f 79.17 3.3506   6 1.3679 0.0423 74.6, 83.4 0.66
LOX_GF m 66.7 0.7   3 0.40415 0.0105 66.0, 67.4 -1.03
LUF_AD m 71.6 3.9217   5 1.7539 0.0548 65.4, 74.4 -0.46
LUG_EH m 83.53 2.7062   3 1.5624 0.0324 80.5, 85.7 0.92
LUS_AH f 85.3 0.0   3 0.0 0.0 85.3, 85.3 1.25
LUV_DG m 72.38 1.9923   4 0.99614 0.0275 70.1, 74.5 -0.37
LUZ_FH f 75.45 3.1807   4 1.5903 0.0422 70.9, 78.3 0.3
LUZ_FH m 72.2 0.0   1   0.0 0.0 72.2, 72.2 -0.39
MERCURI_HF m 80.87 2.0984   3 1.2115 0.0259 78.5, 82.5 0.61
NOD/ShiLtJ f 52.1 36.345   2   25.7 0.6976 26.4, 77.8 -1.96
NOD/ShiLtJ m 62.5 1.5556   2   1.1 0.0249 61.4, 63.6 -1.51
NZO/HlLtJ f 79.1 5.9397   2   4.2 0.0751 74.9, 83.3 0.65
NZO/HlLtJ m 77.95 4.1719   2   2.95 0.0535 75.0, 80.9 0.28
PAT_CD m 79.07 0.11547   3 0.06667 0.0015 79.0, 79.2 0.41
PEF_EC f 78.73 2.9687   3 1.714 0.0377 76.2, 82.0 0.61
PEF_EC m 76.87 2.0207   3 1.1667 0.0263 75.7, 79.2 0.15
POH_DC f 72.07 3.4356   3 1.9835 0.0477 68.1, 74.1 -0.03
PWK/PhJ f 85.5 0.70711   2   0.5 0.0083 85.0, 86.0 1.27
PWK/PhJ m 85.45 3.0406   2   2.15 0.0356 83.3, 87.6 1.14
SEH_AH f 58.5 0.0   1   0.0 0.0 58.5, 58.5 -1.34
SEH_AH m 58.35 3.8127   4 1.9063 0.0653 53.6, 62.5 -1.99
STUCKY_HF f 79.57 3.3005   3 1.9055 0.0415 76.3, 82.9 0.69
STUCKY_HF m 81.9 0.0   1   0.0 0.0 81.9, 81.9 0.73
VIT_ED f 58.4 2.0785   3 1.2 0.0356 57.2, 60.8 -1.35
VUX2_HF m 75.13 2.8024   3 1.618 0.0373 72.4, 78.0 -0.05
WAD f 77.37 2.1079   3 1.217 0.0272 75.6, 79.7 0.48
WSB/EiJ f 66.8 4.8083   2   3.4 0.072 63.4, 70.2 -0.54
WSB/EiJ m 70.0 0.14142   2   0.1 0.002 69.9, 70.1 -0.64
XAD8_BG f 64.2 0.0   1   0.0 0.0 64.2, 64.2 -0.79
XAD8_BG m 71.1 1.562   3 0.90185 0.022 69.3, 72.1 -0.52
XAH3_GH m 80.13 2.7683   3 1.5983 0.0345 77.2, 82.7 0.53
XAS4_AF m 76.33 1.914   3 1.105 0.0251 74.3, 78.1 0.09
XAV_AH m 85.1 0.55678   3 0.32146 0.0065 84.5, 85.6 1.1
XAW2_CD m 78.0 3.9598   2   2.8 0.0508 75.2, 80.8 0.28
XEB2_AG f 88.43 1.1015   3 0.63596 0.0125 87.7, 89.7 1.55
XEB2_AG m 86.37 0.50332   3 0.29059 0.0058 85.9, 86.9 1.25
XEB_AF f 82.75 1.9092   2   1.35 0.0231 81.4, 84.1 1.0
XEB_AF m 81.7 0.0   1   0.0 0.0 81.7, 81.7 0.71
XEQ_EH m 81.6 1.9   3 1.097 0.0233 79.5, 83.2 0.7
XXEN2_DC m 81.13 1.6503   3 0.95277 0.0203 79.3, 82.5 0.64
XXEN3_DC f 56.4 0.0   1   0.0 0.0 56.4, 56.4 -1.54
XXEN3_DC m 66.9 0.0   1   0.0 0.0 66.9, 66.9 -1.0
YOX_DE m 84.53 3.5119   3 2.0276 0.0415 81.2, 88.2 1.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 48.7 7.9289 64.7806 32.6194
129S1/SvImJ m 77.55 7.9289 93.6306 61.4694
A/J f 77.25 7.9289 93.3306 61.1694
A/J m 80.4 7.9289 96.4806 64.3194
CAST/EiJ f 60.65 7.9289 76.7306 44.5694
CAST/EiJ m 90.95 7.9289 107.0306 74.8694
CC012/Geni f 87.3667 6.4739 100.4964 74.2369
CC012/Geni m 88.32 5.0147 98.4903 78.1497
DONNELL_HA f 69.8 7.9289 85.8806 53.7194
DONNELL_HA m 71.1333 6.4739 84.2631 58.0036
LAT_HD f 71.34 5.0147 81.5103 61.1697
LAT_HD m 75.45 7.9289 91.5306 59.3694
NOD/ShiLtJ f 52.1 7.9289 68.1806 36.0194
NOD/ShiLtJ m 62.5 7.9289 78.5806 46.4194
NZO/HlLtJ f 79.1 7.9289 95.1806 63.0194
NZO/HlLtJ m 77.95 7.9289 94.0306 61.8694
PEF_EC f 78.7333 6.4739 91.8631 65.6036
PEF_EC m 76.8667 6.4739 89.9964 63.7369
PWK/PhJ f 85.5 7.9289 101.5806 69.4194
PWK/PhJ m 85.45 7.9289 101.5306 69.3694
WSB/EiJ f 66.8 7.9289 82.8806 50.7194
WSB/EiJ m 70.0 7.9289 86.0806 53.9194
XEB2_AG f 88.4333 6.4739 101.5631 75.3036
XEB2_AG m 86.3667 6.4739 99.4964 73.2369


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 63.125 5.6066 74.4957 51.7543
A/J both 78.825 5.6066 90.1957 67.4543
CAST/EiJ both 75.8 5.6066 87.1707 64.4293
CC012/Geni both 87.8433 4.0945 96.1473 79.5394
DONNELL_HA both 70.4667 5.1181 80.8466 60.0867
LAT_HD both 73.395 4.6908 82.9084 63.8816
NOD/ShiLtJ both 57.3 5.6066 68.6707 45.9293
NZO/HlLtJ both 78.525 5.6066 89.8957 67.1543
PEF_EC both 77.8 4.5778 87.0841 68.5159
PWK/PhJ both 85.475 5.6066 96.8457 74.1043
WSB/EiJ both 68.4 5.6066 79.7707 57.0293
XEB2_AG both 87.4 4.5778 96.6841 78.1159




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA