Phenotype measure:   McMullan6   lean_resp_HIIT

ID, description, units MPD:61543   lean_resp_HIIT   percentage of body mass that is lean, response after 4 wks of treatment   [%]  high intensity group
exercise study
Data set, strains McMullan6   CC   4 strains     sex: both     age: 8-10wks
Procedure MRI
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan6 - percentage of body mass that is lean, response after 4 wks of treatment high intensity group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means-1.10   % -2.00   %
Median of the strain means-1.30   % -1.96   %
SD of the strain means± 1.04 ± 1.14
Coefficient of variation (CV)-0.944 -0.573
Min–max range of strain means-2.12   –   0.336   % -3.36   –   -0.697   %
Mean sample size per strain11.8   mice 9.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 25.0281 25.0281 2.361 0.1286
strain 3 77.2306 25.7435 2.4285 0.0719
sex:strain 3 1.4734 0.4911 0.0463 0.9867
Residuals 75 795.0497 10.6007


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 0.336 3.37   14 0.902 10.0 -3.68, 5.88 1.38
CC002/Unc m -0.697 2.06   6 0.84 -2.95 -2.61, 1.9 1.14
CC013/GeniUnc f -1.16 1.44   4 0.722 -1.24 -2.95, 0.125 -0.06
CC013/GeniUnc m -1.53 1.82   8 0.642 -1.19 -3.61, 1.34 0.41
CC027/GeniUnc f -1.45 1.85   14 0.494 -1.28 -6.18, 0.454 -0.34
CC027/GeniUnc m -2.4 3.63   11 1.1 -1.52 -11.3, 2.38 -0.35
CC037/TauUnc f -2.12 3.54   15 0.915 -1.67 -9.28, 2.56 -0.98
CC037/TauUnc m -3.36 4.94   11 1.49 -1.47 -11.1, 3.47 -1.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 0.3363 0.8702 2.0697 -1.3972
CC002/Unc m -0.6967 1.3292 1.9512 -3.3446
CC013/GeniUnc f -1.1632 1.6279 2.0798 -4.4062
CC013/GeniUnc m -1.5261 1.1511 0.7671 -3.8192
CC027/GeniUnc f -1.4477 0.8702 0.2857 -3.1812
CC027/GeniUnc m -2.3951 0.9817 -0.4395 -4.3507
CC037/TauUnc f -2.1205 0.8407 -0.4458 -3.7951
CC037/TauUnc m -3.3636 0.9817 -1.408 -5.3192


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both -0.1802 0.7943 1.4022 -1.7626
CC013/GeniUnc both -1.3446 0.9969 0.6413 -3.3306
CC027/GeniUnc both -1.9214 0.6559 -0.6148 -3.2281
CC037/TauUnc both -2.742 0.6462 -1.4547 -4.0294




GWAS analysis not available: At least 12 strains are required