Phenotype measure:   McMullan6   lean_resp_MICT

ID, description, units MPD:61542   lean_resp_MICT   percentage of body mass that is lean, response after 4 wks of treatment   [%]  moderate intensity group
exercise study
Data set, strains McMullan6   CC   4 strains     sex: both     age: 8-10wks
Procedure MRI
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan6 - percentage of body mass that is lean, response after 4 wks of treatment moderate intensity group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means-3.49   % -1.47   %
Median of the strain means-2.40   % -1.49   %
SD of the strain means± 3.41 ± 1.74
Coefficient of variation (CV)-0.977 -1.18
Min–max range of strain means-8.46   –   -0.712   % -3.57   –   0.662   %
Mean sample size per strain13.5   mice 9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 104.5452 104.5452 8.1214 0.0055
strain 3 458.3931 152.7977 11.8698 < 0.0001
sex:strain 3 90.8835 30.2945 2.3534 0.0779
Residuals 84 1081.3197 12.8729


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f -2.25 4.56   16 1.14 -2.03 -7.96, 9.41 0.36
CC002/Unc m 0.662 1.0   8 0.355 1.52 -0.536, 2.62 1.23
CC013/GeniUnc f -0.712 1.91   8 0.675 -2.68 -2.81, 2.53 0.82
CC013/GeniUnc m -1.26 2.59   8 0.916 -2.05 -4.78, 2.55 0.12
CC027/GeniUnc f -2.54 2.18   15 0.562 -0.859 -7.09, -0.307 0.28
CC027/GeniUnc m -1.72 3.19   11 0.962 -1.85 -8.15, 3.44 -0.14
CC037/TauUnc f -8.46 4.86   15 1.26 -0.575 -14.5, -0.165 -1.46
CC037/TauUnc m -3.57 4.36   11 1.31 -1.22 -10.1, 3.01 -1.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f -2.2451 0.897 -0.4614 -4.0288
CC002/Unc m 0.6618 1.2685 3.1843 -1.8608
CC013/GeniUnc f -0.7117 1.2685 1.8109 -3.2342
CC013/GeniUnc m -1.2614 1.2685 1.2611 -3.784
CC027/GeniUnc f -2.535 0.9264 -0.6928 -4.3772
CC027/GeniUnc m -1.7237 1.0818 0.4275 -3.875
CC037/TauUnc f -8.4591 0.9264 -6.6169 -10.3014
CC037/TauUnc m -3.5733 1.0818 -1.422 -5.7245


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both -0.7917 0.7768 0.7531 -2.3364
CC013/GeniUnc both -0.9865 0.897 0.7972 -2.7703
CC027/GeniUnc both -2.1294 0.7121 -0.7132 -3.5455
CC037/TauUnc both -6.0162 0.7121 -4.6001 -7.4323




GWAS analysis not available: At least 12 strains are required