Phenotype measure:   McMullan6   lean_resp_ctrl

ID, description, units MPD:61541   lean_resp_ctrl   percentage of body mass that is lean, response after 4 wks of treatment   [%]  no exercise group
exercise study
Data set, strains McMullan6   CC   4 strains     sex: both     age: 8-10wks
Procedure MRI
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan6 - percentage of body mass that is lean, response after 4 wks of treatment no exercise group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means-2.01   % -1.52   %
Median of the strain means-2.40   % -1.45   %
SD of the strain means± 1.60 ± 0.766
Coefficient of variation (CV)-0.795 -0.503
Min–max range of strain means-3.49   –   0.252   % -2.42   –   -0.776   %
Mean sample size per strain7.8   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.9808 2.9808 0.4901 0.4869
strain 3 56.058 18.686 3.072 0.0352
sex:strain 3 16.8251 5.6084 0.922 0.4363
Residuals 55 334.5477 6.0827


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f -2.27 2.63   8 0.929 -1.16 -5.45, 2.34 -0.16
CC002/Unc m -1.01 3.68   8 1.3 -3.64 -8.62, 3.12 0.67
CC013/GeniUnc f -2.52 2.29   8 0.809 -0.91 -6.36, -0.123 -0.32
CC013/GeniUnc m -2.42 2.07   8 0.733 -0.857 -5.55, 0.144 -1.17
CC027/GeniUnc f 0.252 1.57   8 0.556 6.23 -1.5, 2.97 1.42
CC027/GeniUnc m -0.776 1.63   8 0.577 -2.1 -2.59, 2.59 0.98
CC037/TauUnc f -3.49 3.59   7 1.36 -1.03 -7.22, 3.76 -0.93
CC037/TauUnc m -1.89 1.28   8 0.451 -0.676 -3.69, -0.109 -0.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f -2.2666 0.872 -0.5191 -4.014
CC002/Unc m -1.0102 0.872 0.7373 -2.7576
CC013/GeniUnc f -2.5161 0.872 -0.7687 -4.2636
CC013/GeniUnc m -2.4183 0.872 -0.6708 -4.1658
CC027/GeniUnc f 0.2524 0.872 1.9999 -1.4951
CC027/GeniUnc m -0.7758 0.872 0.9717 -2.5232
CC037/TauUnc f -3.4932 0.9322 -1.6251 -5.3614
CC037/TauUnc m -1.887 0.872 -0.1395 -3.6345


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both -1.6384 0.6166 -0.4027 -2.874
CC013/GeniUnc both -2.4672 0.6166 -1.2316 -3.7029
CC027/GeniUnc both -0.2617 0.6166 0.974 -1.4973
CC037/TauUnc both -2.6901 0.6382 -1.4111 -3.9691




GWAS analysis not available: At least 12 strains are required