Project measure / variable:   McMullan6   fat_resp_MICT

ID, description, units MPD:61527   fat_resp_MICT   percentage of body mass that is fat, response after 4 wks of treatment   [%]  moderate intensity group  
exercise study
Data set, strains McMullan6   CC   4 strains     sex: both     age: 8-10wks
Procedure MRI
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan6 - percentage of body mass that is fat, response after 4 wks of treatment moderate intensity group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means31.8   % 11.2   %
Median of the strain means22.8   % 11.1   %
SD of the strain means± 33.4 ± 20.5
Coefficient of variation (CV)1.05 1.83
Min–max range of strain means2.54   –   79.0   % -13.8   –   36.3   %
Mean sample size per strain13.5   mice 9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 10788.2379 10788.2379 4.8753 0.03
strain 3 49009.4988 16336.4996 7.3825 0.0002
sex:strain 3 6519.4589 2173.153 0.9821 0.4053
Residuals 84 185880.0178 2212.8574


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 15.8 33.9   16 8.47 2.14 -63.5, 77.7 -0.48
CC002/Unc m -13.8 26.4   8 9.33 -1.91 -58.7, 25.8 -1.22
CC013/GeniUnc f 2.54 34.4   8 12.2 13.5 -42.5, 53.8 -0.88
CC013/GeniUnc m 9.59 45.4   8 16.1 4.74 -46.1, 76.1 -0.08
CC027/GeniUnc f 29.8 60.2   15 15.6 2.02 -21.8, 217.0 -0.06
CC027/GeniUnc m 12.6 44.6   11 13.4 3.53 -51.1, 93.4 0.07
CC037/TauUnc f 79.0 62.5   15 16.1 0.791 -0.945, 193.0 1.41
CC037/TauUnc m 36.3 39.7   11 12.0 1.09 -15.4, 116.0 1.23


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 15.8394 11.7603 39.2259 -7.5472
CC002/Unc m -13.7956 16.6315 19.278 -46.8692
CC013/GeniUnc f 2.5438 16.6315 35.6174 -30.5298
CC013/GeniUnc m 9.5949 16.6315 42.6685 -23.4787
CC027/GeniUnc f 29.7663 12.1459 53.9198 5.6128
CC027/GeniUnc m 12.6329 14.1834 40.8382 -15.5723
CC037/TauUnc f 78.9762 12.1459 103.1297 54.8226
CC037/TauUnc m 36.3104 14.1834 64.5157 8.1052


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 1.0219 10.1847 21.2752 -19.2315
CC013/GeniUnc both 6.0693 11.7603 29.4559 -17.3172
CC027/GeniUnc both 21.1996 9.3367 39.7666 2.6326
CC037/TauUnc both 57.6433 9.3367 76.2103 39.0763




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA