Project measure / variable:   McMullan6   fat_resp_ctrl

ID, description, units MPD:61526   fat_resp_ctrl   percentage of body mass that is fat, response after 4 wks of treatment   [%]  no exercise group  
exercise study
Data set, strains McMullan6   CC   4 strains     sex: both     age: 8-10wks
Procedure MRI
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  STRAIN COMPARISON PLOT
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McMullan6 - percentage of body mass that is fat, response after 4 wks of treatment no exercise group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means23.5   % 20.4   %
Median of the strain means27.5   % 26.4   %
SD of the strain means± 24.8 ± 22.9
Coefficient of variation (CV)1.05 1.12
Min–max range of strain means-8.24   –   47.3   % -9.85   –   38.7   %
Mean sample size per strain7.8   mice 7.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 45.7994 45.7994 0.0237 0.8781
strain 3 12353.6261 4117.8754 2.1342 0.1066
sex:strain 3 13752.8108 4584.2703 2.376 0.0801
Residuals 54 104189.5298 1929.4357


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 16.8 23.6   8 8.33 1.4 -14.0, 52.9 -0.27
CC002/Unc m -9.85 13.5   7 5.09 -1.37 -27.2, 5.51 -1.32
CC013/GeniUnc f 47.3 55.0   8 19.4 1.16 8.61, 169.0 0.96
CC013/GeniUnc m 37.5 45.3   8 16.0 1.21 -5.89, 128.0 0.75
CC027/GeniUnc f -8.24 45.0   8 15.9 -5.46 -53.0, 92.2 -1.28
CC027/GeniUnc m 38.7 73.8   8 26.1 1.91 -37.4, 174.0 0.8
CC037/TauUnc f 38.3 39.8   7 15.0 1.04 -25.0, 106.0 0.6
CC037/TauUnc m 15.3 16.4   8 5.78 1.07 -5.45, 36.7 -0.22


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 16.8464 15.53 47.9821 -14.2892
CC002/Unc m -9.8503 16.6022 23.4351 -43.1357
CC013/GeniUnc f 47.3473 15.53 78.483 16.2117
CC013/GeniUnc m 37.5178 15.53 68.6535 6.3822
CC027/GeniUnc f -8.2436 15.53 22.8921 -39.3793
CC027/GeniUnc m 38.6799 15.53 69.8155 7.5442
CC037/TauUnc f 38.3407 16.6022 71.6261 5.0552
CC037/TauUnc m 15.2587 15.53 46.3943 -15.877


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 3.4981 11.3668 26.2871 -19.2909
CC013/GeniUnc both 42.4326 10.9813 64.4488 20.4163
CC027/GeniUnc both 15.2181 10.9813 37.2344 -6.7981
CC037/TauUnc both 26.7997 11.3668 49.5887 4.0107




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA