Phenotype measure:   McMullan6   fat_end_MICT

ID, description, units MPD:61522   fat_end_MICT   percentage of body mass that is fat after 4 wks of treatment   [%]  moderate intensity group
exercise study
Data set, strains McMullan6   CC   4 strains     sex: both     age: 8-10wks
Procedure MRI
Ontology mappings

  STRAIN COMPARISON PLOT
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McMullan6 - percentage of body mass that is fat after 4 wks of treatment moderate intensity group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means9.77   % 7.93   %
Median of the strain means8.57   % 6.91   %
SD of the strain means± 5.94 ± 3.59
Coefficient of variation (CV)0.608 0.453
Min–max range of strain means4.72   –   17.2   % 4.80   –   13.1   %
Mean sample size per strain13.5   mice 9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 102.3715 102.3715 9.3138 0.003
strain 3 1608.0179 536.006 48.766 < 0.0001
sex:strain 3 204.2504 68.0835 6.1943 0.0007
Residuals 84 923.2767 10.9914


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 11.9 3.48   16 0.871 0.293 3.89, 17.5 0.36
CC002/Unc m 6.83 2.92   8 1.03 0.427 2.17, 11.3 -0.31
CC013/GeniUnc f 5.24 1.59   8 0.563 0.304 2.77, 7.39 -0.76
CC013/GeniUnc m 4.8 2.38   8 0.842 0.496 1.8, 9.41 -0.87
CC027/GeniUnc f 4.72 2.15   15 0.554 0.455 2.03, 9.56 -0.85
CC027/GeniUnc m 6.98 3.16   11 0.954 0.453 2.75, 14.5 -0.26
CC037/TauUnc f 17.2 4.98   15 1.28 0.289 9.64, 29.1 1.25
CC037/TauUnc m 13.1 3.36   11 1.01 0.258 8.35, 18.5 1.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 11.8914 0.8288 13.5397 10.2432
CC002/Unc m 6.8325 1.1721 9.1635 4.5016
CC013/GeniUnc f 5.2395 1.1721 7.5704 2.9086
CC013/GeniUnc m 4.8041 1.1721 7.135 2.4731
CC027/GeniUnc f 4.7168 0.856 6.4191 3.0145
CC027/GeniUnc m 6.9812 0.9996 8.969 4.9934
CC037/TauUnc f 17.2146 0.856 18.9169 15.5123
CC037/TauUnc m 13.0534 0.9996 15.0412 11.0655


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 9.362 0.7178 10.7894 7.9346
CC013/GeniUnc both 5.0218 0.8288 6.67 3.3736
CC027/GeniUnc both 5.849 0.658 7.1575 4.5404
CC037/TauUnc both 15.134 0.658 16.4425 13.8254




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA