Phenotype measure:   Palmer6   ASR

ID, description, units MPD:59841   ASR   acoustic startle response (ASR) evoked by 120 dB sound pressure level   [amplitude]
Data set, strains Palmer6   F1 Cacna1c   30 strains     sex: both     age: 7-14wks
Procedure acoustic startle test
Ontology mappings

  STRAIN COMPARISON PLOT
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Palmer6 - acoustic startle response (ASR) evoked by 120 dB sound pressure level



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means40.9   amplitude 54.8   amplitude
Median of the strain means32.6   amplitude 40.1   amplitude
SD of the strain means± 23.1 ± 38.4
Coefficient of variation (CV)0.564 0.699
Min–max range of strain means11.1   –   88.1   amplitude 10.0   –   134   amplitude
Mean sample size per strain5.7   mice 5.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 20184.7635 20184.7635 29.6748 < 0.0001
strain 29 302395.7639 10427.4401 15.33 < 0.0001
sex:strain 29 38108.3267 1314.0802 1.9319 0.0036
Residuals 301 204739.6374 680.1981


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129SB6F1 f 77.4 50.6   5 22.6 0.653 38.1, 164.0 1.58
129SB6F1 m 125.0 50.8   5 22.7 0.407 78.3, 205.0 1.83
AB6F1 f 17.7 7.69   6 3.14 0.436 8.5, 29.8 -1.0
AB6F1 m 39.8 32.7   7 12.4 0.823 24.0, 113.0 -0.39
AKB6F1 f 23.2 8.86   6 3.62 0.381 14.6, 33.9 -0.77
AKB6F1 m 24.5 9.12   5 4.08 0.372 15.2, 35.4 -0.79
BKSB6F1 f 22.5 6.76   6 2.76 0.301 15.7, 34.5 -0.8
BKSB6F1 m 37.0 24.4   6 9.95 0.659 7.6, 65.5 -0.46
BTBRB6F1 f 85.0 41.0   5 18.4 0.483 53.6, 149.0 1.91
BTBRB6F1 m 49.9 19.4   6 7.92 0.389 29.0, 79.3 -0.13
BUB6F1 f 28.0 10.4   4 5.22 0.373 13.6, 35.8 -0.56
BUB6F1 m 31.3 13.0   5 5.82 0.416 12.8, 45.8 -0.61
C3B6F1 f 53.7 56.4   5 25.2 1.05 12.8, 153.0 0.56
C3B6F1 m 81.3 24.6   5 11.0 0.302 50.0, 114.0 0.69
C57BL/6J f 34.7 23.1   17 5.6 0.666 7.9, 91.3 -0.27
C57BL/6J m 28.9 16.0   15 4.14 0.556 8.5, 67.7 -0.68
C58B6F1 f 11.1 3.9   5 1.74 0.351 7.0, 14.9 -1.29
C58B6F1 m 11.4 4.37   5 1.95 0.385 6.5, 16.0 -1.13
CBAB6F1 f 66.8 21.7   6 8.85 0.324 41.7, 93.2 1.12
CBAB6F1 m 116.0 31.3   8 11.1 0.27 73.1, 168.0 1.6
CByB6F1 f 19.2 9.81   6 4.01 0.51 6.3, 32.4 -0.94
CByB6F1 m 20.1 7.83   5 3.5 0.39 14.4, 33.8 -0.91
D2B6F1 f 19.4 7.05   6 2.88 0.363 8.5, 26.0 -0.93
D2B6F1 m 29.3 18.0   5 8.04 0.613 11.7, 59.2 -0.67
DDYB6F1 f 73.9 31.2   6 12.7 0.422 40.5, 125.0 1.43
DDYB6F1 m 123.0 54.4   7 20.6 0.444 57.1, 190.0 1.78
FVBB6F1 f 38.9 22.2   5 9.92 0.57 20.9, 74.7 -0.09
FVBB6F1 m 40.5 30.9   6 12.6 0.764 2.7, 76.4 -0.37
IB6F1 f 54.7 15.0   4 7.49 0.274 38.5, 69.3 0.6
IB6F1 m 113.0 42.1   6 17.2 0.374 64.3, 176.0 1.52
KKB6F1 f 67.5 18.8   6 7.68 0.279 42.3, 93.0 1.15
KKB6F1 m 97.0 51.8   5 23.1 0.534 44.6, 176.0 1.1
LGB6F1 f 48.8 8.04   6 3.28 0.165 39.4, 61.6 0.34
LGB6F1 m 47.8 21.6   7 8.17 0.452 27.2, 89.4 -0.18
LPB6F1 f 15.5 21.8   6 8.91 1.41 5.3, 60.0 -1.1
LPB6F1 m 10.0 5.4   5 2.42 0.538 4.8, 18.0 -1.17
MAB6F1 f 16.4 7.47   6 3.05 0.455 7.8, 29.6 -1.06
MAB6F1 m 22.4 17.7   6 7.22 0.788 10.8, 57.6 -0.85
MRLB6F1 f 53.6 27.8   6 11.4 0.518 32.8, 108.0 0.55
MRLB6F1 m 57.6 14.2   6 5.79 0.246 40.0, 79.3 0.07
NODB6F1 f 30.5 23.7   7 8.94 0.776 8.3, 68.1 -0.45
NODB6F1 m 44.5 21.0   6 8.55 0.471 20.2, 71.3 -0.27
NONB6F1 f 23.8 9.55   5 4.27 0.401 11.1, 37.0 -0.74
NONB6F1 m 30.6 2.84   4 1.42 0.0928 27.5, 34.3 -0.63
NZBB6F1 f 45.9 18.0   6 7.34 0.392 18.9, 69.3 0.22
NZBB6F1 m 62.5 36.6   6 15.0 0.586 21.8, 110.0 0.2
NZWB6F1 f 61.6 12.9   6 5.29 0.21 48.0, 82.3 0.9
NZWB6F1 m 93.5 36.7   5 16.4 0.393 56.9, 142.0 1.01
PLB6F1 f 17.6 5.38   5 2.41 0.305 11.7, 25.7 -1.01
PLB6F1 m 11.9 5.05   5 2.26 0.424 8.3, 20.6 -1.12
RIIIB6F1 f 88.1 18.7   6 7.62 0.212 52.1, 105.0 2.05
RIIIB6F1 m 134.0 54.8   6 22.4 0.408 73.4, 224.0 2.06
SEAB6F1 f 17.4 6.92   6 2.82 0.398 8.5, 27.5 -1.02
SEAB6F1 m 19.2 11.0   5 4.9 0.571 7.6, 34.8 -0.93
SJLB6F1 f 28.3 22.8   6 9.29 0.803 10.6, 67.0 -0.55
SJLB6F1 m 30.8 12.7   6 5.18 0.411 17.7, 53.4 -0.63
SMB6F1 f 54.9 44.4   6 18.1 0.809 28.1, 144.0 0.61
SMB6F1 m 83.3 32.9   6 13.4 0.394 51.0, 138.0 0.74
SWRB6F1 f 30.3 24.7   6 10.1 0.816 6.1, 68.6 -0.46
SWRB6F1 m 28.8 16.5   6 6.75 0.574 9.0, 55.5 -0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 f 77.42 11.6636 100.3725 54.4675
129SB6F1 m 124.88 11.6636 147.8325 101.9275
AB6F1 f 17.65 10.6474 38.6027 0.0
AB6F1 m 39.7714 9.8575 59.1699 20.373
AKB6F1 f 23.2333 10.6474 44.186 2.2806
AKB6F1 m 24.48 11.6636 47.4325 1.5275
BKSB6F1 f 22.4667 10.6474 43.4194 1.514
BKSB6F1 m 37.0 10.6474 57.9527 16.0473
BTBRB6F1 f 85.04 11.6636 107.9925 62.0875
BTBRB6F1 m 49.9167 10.6474 70.8694 28.964
BUB6F1 f 28.0 13.0403 53.6617 2.3383
BUB6F1 m 31.28 11.6636 54.2325 8.3275
C3B6F1 f 53.74 11.6636 76.6925 30.7875
C3B6F1 m 81.3 11.6636 104.2525 58.3475
C57BL/6J f 34.6941 6.3255 47.1419 22.2464
C57BL/6J m 28.8667 6.734 42.1183 15.615
C58B6F1 f 11.12 11.6636 34.0725 0.0
C58B6F1 m 11.36 11.6636 34.3125 0.0
CBAB6F1 f 66.8333 10.6474 87.786 45.8806
CBAB6F1 m 115.875 9.2209 134.0206 97.7294
CByB6F1 f 19.2333 10.6474 40.186 0.0
CByB6F1 m 20.06 11.6636 43.0125 0.0
D2B6F1 f 19.4 10.6474 40.3527 0.0
D2B6F1 m 29.32 11.6636 52.2725 6.3675
DDYB6F1 f 73.8667 10.6474 94.8194 52.914
DDYB6F1 m 122.5714 9.8575 141.9699 103.173
FVBB6F1 f 38.94 11.6636 61.8925 15.9875
FVBB6F1 m 40.4667 10.6474 61.4194 19.514
IB6F1 f 54.65 13.0403 80.3117 28.9883
IB6F1 m 112.5667 10.6474 133.5194 91.614
KKB6F1 f 67.5167 10.6474 88.4694 46.564
KKB6F1 m 97.0 11.6636 119.9525 74.0475
LGB6F1 f 48.7833 10.6474 69.736 27.8306
LGB6F1 m 47.7714 9.8575 67.1699 28.373
LPB6F1 f 15.4667 10.6474 36.4194 0.0
LPB6F1 m 10.04 11.6636 32.9925 0.0
MAB6F1 f 16.4167 10.6474 37.3694 0.0
MAB6F1 m 22.4333 10.6474 43.386 1.4806
MRLB6F1 f 53.6333 10.6474 74.586 32.6806
MRLB6F1 m 57.6 10.6474 78.5527 36.6473
NODB6F1 f 30.4714 9.8575 49.8699 11.073
NODB6F1 m 44.4667 10.6474 65.4194 23.514
NONB6F1 f 23.82 11.6636 46.7725 0.8675
NONB6F1 m 30.575 13.0403 56.2367 4.9133
NZBB6F1 f 45.85 10.6474 66.8027 24.8973
NZBB6F1 m 62.45 10.6474 83.4027 41.4973
NZWB6F1 f 61.6 10.6474 82.5527 40.6473
NZWB6F1 m 93.54 11.6636 116.4925 70.5875
PLB6F1 f 17.64 11.6636 40.5925 0.0
PLB6F1 m 11.92 11.6636 34.8725 0.0
RIIIB6F1 f 88.0667 10.6474 109.0194 67.114
RIIIB6F1 m 134.2833 10.6474 155.236 113.3306
SEAB6F1 f 17.3833 10.6474 38.336 0.0
SEAB6F1 m 19.2 11.6636 42.1525 0.0
SJLB6F1 f 28.3333 10.6474 49.286 7.3806
SJLB6F1 m 30.85 10.6474 51.8027 9.8973
SMB6F1 f 54.9333 10.6474 75.886 33.9806
SMB6F1 m 83.3 10.6474 104.2527 62.3473
SWRB6F1 f 30.3167 10.6474 51.2694 9.364
SWRB6F1 m 28.8 10.6474 49.7527 7.8473


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 both 101.15 8.2474 117.3799 84.9201
AB6F1 both 28.7107 7.255 42.9876 14.4339
AKB6F1 both 23.8567 7.8963 39.3956 8.3177
BKSB6F1 both 29.7333 7.5288 44.5491 14.9175
BTBRB6F1 both 67.4783 7.8963 83.0173 51.9394
BUB6F1 both 29.64 8.7477 46.8544 12.4256
C3B6F1 both 67.52 8.2474 83.7499 51.2901
C57BL/6J both 31.7804 4.6195 40.8709 22.6898
C58B6F1 both 11.24 8.2474 27.4699 0.0
CBAB6F1 both 91.3542 7.0426 105.2131 77.4953
CByB6F1 both 19.6467 7.8963 35.1856 4.1077
D2B6F1 both 24.36 7.8963 39.8989 8.8211
DDYB6F1 both 98.219 7.255 112.4959 83.9422
FVBB6F1 both 39.7033 7.8963 55.2423 24.1644
IB6F1 both 83.6083 8.4175 100.1729 67.0438
KKB6F1 both 82.2583 7.8963 97.7973 66.7194
LGB6F1 both 48.2774 7.255 62.5542 34.0005
LPB6F1 both 12.7533 7.8963 28.2923 0.0
MAB6F1 both 19.425 7.5288 34.2408 4.6092
MRLB6F1 both 55.6167 7.5288 70.4325 40.8009
NODB6F1 both 37.469 7.255 51.7459 23.1922
NONB6F1 both 27.1975 8.7477 44.4119 9.9831
NZBB6F1 both 54.15 7.5288 68.9658 39.3342
NZWB6F1 both 77.57 7.8963 93.1089 62.0311
PLB6F1 both 14.78 8.2474 31.0099 0.0
RIIIB6F1 both 111.175 7.5288 125.9908 96.3592
SEAB6F1 both 18.2917 7.8963 33.8306 2.7527
SJLB6F1 both 29.5917 7.5288 44.4075 14.7759
SMB6F1 both 69.1167 7.5288 83.9325 54.3009
SWRB6F1 both 29.5583 7.5288 44.3741 14.7425




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA