Phenotype measure

ID, description, units MPD:59341   ASR   acoustic startle response (ASR) evoked by 120 dB sound pressure level   [amplitude]
Data set, strains Palmer4   F1 Cacna1c   30 strains     sex: both     age: 7-14wks
Procedure acoustic startle test
Ontology mappings


  STRAIN COMPARISON PLOT
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Palmer4 - acoustic startle response (ASR) evoked by 120 dB sound pressure level



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means33.8   amplitude 53.1   amplitude
Median of the strain means31.5   amplitude 35.2   amplitude
SD of the strain means± 19.9 ± 35.5
Coefficient of variation (CV)0.587 0.668
Min–max range of strain means6.10   –   89.8   amplitude 10.7   –   136   amplitude
Mean sample size per strain5.6   mice 5.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 25218.3772 25218.3772 39.6605 < 0.0001
strain 29 225800.69 7786.2307 12.2453 < 0.0001
sex:strain 29 46240.9755 1594.5164 2.5077 0.0001
Residuals 290 184398.2858 635.8562


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(129S x B6-Cacna1c)F1 f 60.5 37.8   7 14.3 0.625 16.2, 116.0 1.34
(129S x B6-Cacna1c)F1 m 99.6 66.3   5 29.7 0.666 26.0, 194.0 1.31
(AJ x B6-Cacna1c)F1 f 22.3 12.3   6 5.03 0.552 8.5, 42.4 -0.58
(AJ x B6-Cacna1c)F1 m 26.2 8.0   6 3.26 0.305 14.6, 36.0 -0.76
(AKR x B6-Cacna1c)F1 f 15.0 8.18   5 3.66 0.547 9.3, 29.4 -0.95
(AKR x B6-Cacna1c)F1 m 23.8 8.27   5 3.7 0.347 15.0, 36.2 -0.83
(B6 x B6-Cacna1c)F1 f 26.8 18.5   15 4.77 0.689 7.1, 65.4 -0.35
(B6 x B6-Cacna1c)F1 m 25.0 20.0   15 5.17 0.801 9.3, 69.5 -0.79
(BALB x B6-Cacna1c)F1 f 13.8 5.92   6 2.42 0.428 9.0, 22.4 -1.01
(BALB x B6-Cacna1c)F1 m 15.8 10.7   6 4.36 0.675 6.6, 31.1 -1.05
(BLKS x B6-Cacna1c)F1 f 22.0 24.3   5 10.9 1.1 5.7, 65.1 -0.6
(BLKS x B6-Cacna1c)F1 m 29.3 21.9   6 8.93 0.746 12.5, 70.6 -0.67
(BTBR x B6-Cacna1c)F1 f 48.1 19.3   7 7.28 0.401 14.2, 67.0 0.72
(BTBR x B6-Cacna1c)F1 m 75.9 72.4   6 29.6 0.954 14.0, 211.0 0.64
(BUB x B6-Cacna1c)F1 f 26.2 11.9   5 5.34 0.456 10.6, 39.2 -0.38
(BUB x B6-Cacna1c)F1 m 33.3 12.2   5 5.46 0.366 20.2, 49.1 -0.56
(C3H x B6-Cacna1c)F1 f 44.4 16.6   6 6.76 0.374 24.3, 65.2 0.53
(C3H x B6-Cacna1c)F1 m 90.9 48.7   5 21.8 0.536 52.0, 172.0 1.06
(C58 x B6-Cacna1c)F1 f 11.8 6.38   6 2.61 0.542 5.7, 22.4 -1.11
(C58 x B6-Cacna1c)F1 m 23.1 19.3   6 7.87 0.837 6.5, 48.5 -0.85
(CBA x B6-Cacna1c)F1 f 50.8 18.3   4 9.13 0.36 32.4, 66.6 0.85
(CBA x B6-Cacna1c)F1 m 92.1 50.0   4 25.0 0.543 35.3, 154.0 1.1
(DBA x B6-Cacna1c)F1 f 15.1 10.3   5 4.6 0.681 5.8, 31.8 -0.94
(DBA x B6-Cacna1c)F1 m 20.6 10.1   6 4.11 0.488 10.2, 37.3 -0.92
(DDY x B6-Cacna1c)F1 f 50.7 45.8   5 20.5 0.902 14.1, 128.0 0.85
(DDY x B6-Cacna1c)F1 m 37.2 11.9   5 5.3 0.319 20.3, 48.6 -0.45
(FVB x B6-Cacna1c)F1 f 45.3 25.9   6 10.6 0.571 21.3, 91.4 0.58
(FVB x B6-Cacna1c)F1 m 64.6 30.8   6 12.6 0.477 16.0, 102.0 0.32
(ILN x B6-Cacna1c)F1 f 69.7 14.5   6 5.93 0.208 43.9, 83.2 1.81
(ILN x B6-Cacna1c)F1 m 91.2 21.3   5 9.52 0.233 65.8, 122.0 1.07
(KK x B6-Cacna1c)F1 f 36.1 12.9   6 5.26 0.356 21.1, 55.8 0.11
(KK x B6-Cacna1c)F1 m 103.0 40.8   6 16.7 0.395 58.6, 159.0 1.41
(LG x B6-Cacna1c)F1 f 40.7 13.9   6 5.69 0.342 14.2, 51.4 0.35
(LG x B6-Cacna1c)F1 m 56.0 17.1   6 6.97 0.305 33.6, 76.7 0.08
(LP x B6-Cacna1c)F1 f 6.1 2.33   5 1.04 0.382 3.8, 9.9 -1.4
(LP x B6-Cacna1c)F1 m 10.7 6.4   5 2.86 0.598 6.4, 21.9 -1.2
(MA x B6-Cacna1c)F1 f 13.8 4.6   6 1.88 0.332 9.2, 20.7 -1.01
(MA x B6-Cacna1c)F1 m 21.7 6.48   6 2.65 0.298 10.9, 28.1 -0.89
(MRL x B6-Cacna1c)F1 f 55.4 21.5   6 8.76 0.387 33.7, 86.5 1.09
(MRL x B6-Cacna1c)F1 m 56.5 19.7   5 8.8 0.348 40.5, 80.0 0.09
(NOD x B6-Cacna1c)F1 f 17.2 11.1   6 4.54 0.644 10.1, 39.3 -0.84
(NOD x B6-Cacna1c)F1 m 26.0 16.9   6 6.89 0.649 12.0, 54.8 -0.77
(NON x B6-Cacna1c)F1 f 18.7 4.48   5 2.0 0.239 14.7, 25.7 -0.76
(NON x B6-Cacna1c)F1 m 27.8 7.43   5 3.32 0.268 17.8, 35.6 -0.71
(NZB x B6-Cacna1c)F1 f 36.5 18.2   6 7.43 0.499 14.9, 64.8 0.13
(NZB x B6-Cacna1c)F1 m 27.5 17.8   5 7.94 0.645 12.5, 58.0 -0.72
(NZW x B6-Cacna1c)F1 f 44.1 28.0   4 14.0 0.636 18.4, 74.1 0.52
(NZW x B6-Cacna1c)F1 m 136.0 66.6   5 29.8 0.489 61.1, 225.0 2.34
(PL x B6-Cacna1c)F1 f 14.3 2.84   4 1.42 0.199 11.4, 17.1 -0.98
(PL x B6-Cacna1c)F1 m 25.2 11.0   6 4.49 0.436 16.5, 46.8 -0.79
(RIII x B6-Cacna1c)F1 f 89.8 39.6   6 16.2 0.441 47.5, 140.0 2.82
(RIII x B6-Cacna1c)F1 m 114.0 27.7   6 11.3 0.244 77.1, 150.0 1.72
(SEA x B6-Cacna1c)F1 f 38.3 20.4   6 8.35 0.534 11.1, 66.1 0.22
(SEA x B6-Cacna1c)F1 m 27.9 10.6   6 4.33 0.38 16.0, 43.2 -0.71
(SJL x B6-Cacna1c)F1 f 18.7 9.39   6 3.83 0.502 7.7, 28.9 -0.76
(SJL x B6-Cacna1c)F1 m 56.5 26.7   6 10.9 0.473 27.9, 94.8 0.09
(SM x B6-Cacna1c)F1 f 45.2 15.6   5 6.97 0.345 25.8, 66.9 0.57
(SM x B6-Cacna1c)F1 m 108.0 36.2   6 14.8 0.335 70.0, 150.0 1.55
(SWR x B6-Cacna1c)F1 f 17.9 13.0   6 5.32 0.728 7.5, 42.3 -0.8
(SWR x B6-Cacna1c)F1 m 49.0 9.01   3 5.2 0.184 38.9, 56.2 -0.12


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Cacna1c)F1 f 60.5 9.5308 79.2584 41.7416
(129S x B6-Cacna1c)F1 m 99.62 11.277 121.8152 77.4248
(AJ x B6-Cacna1c)F1 f 22.3167 10.2945 42.578 2.0553
(AJ x B6-Cacna1c)F1 m 26.1833 10.2945 46.4447 5.922
(AKR x B6-Cacna1c)F1 f 14.96 11.277 37.1552 0.0
(AKR x B6-Cacna1c)F1 m 23.82 11.277 46.0152 1.6248
(B6 x B6-Cacna1c)F1 f 26.8333 6.5108 39.6477 14.0189
(B6 x B6-Cacna1c)F1 m 24.9933 6.5108 37.8077 12.1789
(BALB x B6-Cacna1c)F1 f 13.8167 10.2945 34.078 0.0
(BALB x B6-Cacna1c)F1 m 15.8 10.2945 36.0613 0.0
(BLKS x B6-Cacna1c)F1 f 22.02 11.277 44.2152 0.0
(BLKS x B6-Cacna1c)F1 m 29.3167 10.2945 49.578 9.0553
(BTBR x B6-Cacna1c)F1 f 48.1 9.5308 66.8584 29.3416
(BTBR x B6-Cacna1c)F1 m 75.9333 10.2945 96.1947 55.672
(BUB x B6-Cacna1c)F1 f 26.18 11.277 48.3752 3.9848
(BUB x B6-Cacna1c)F1 m 33.34 11.277 55.5352 11.1448
(C3H x B6-Cacna1c)F1 f 44.35 10.2945 64.6113 24.0887
(C3H x B6-Cacna1c)F1 m 90.88 11.277 113.0752 68.6848
(C58 x B6-Cacna1c)F1 f 11.7833 10.2945 32.0447 0.0
(C58 x B6-Cacna1c)F1 m 23.05 10.2945 43.3113 2.7887
(CBA x B6-Cacna1c)F1 f 50.75 12.6081 75.565 25.935
(CBA x B6-Cacna1c)F1 m 92.075 12.6081 116.89 67.26
(DBA x B6-Cacna1c)F1 f 15.08 11.277 37.2752 0.0
(DBA x B6-Cacna1c)F1 m 20.6167 10.2945 40.878 0.3553
(DDY x B6-Cacna1c)F1 f 50.74 11.277 72.9352 28.5448
(DDY x B6-Cacna1c)F1 m 37.16 11.277 59.3552 14.9648
(FVB x B6-Cacna1c)F1 f 45.3333 10.2945 65.5947 25.072
(FVB x B6-Cacna1c)F1 m 64.5833 10.2945 84.8447 44.322
(ILN x B6-Cacna1c)F1 f 69.7 10.2945 89.9613 49.4387
(ILN x B6-Cacna1c)F1 m 91.22 11.277 113.4152 69.0248
(KK x B6-Cacna1c)F1 f 36.15 10.2945 56.4113 15.8887
(KK x B6-Cacna1c)F1 m 103.2833 10.2945 123.5447 83.022
(LG x B6-Cacna1c)F1 f 40.7167 10.2945 60.978 20.4553
(LG x B6-Cacna1c)F1 m 55.9833 10.2945 76.2447 35.722
(LP x B6-Cacna1c)F1 f 6.1 11.277 28.2952 0.0
(LP x B6-Cacna1c)F1 m 10.7 11.277 32.8952 0.0
(MA x B6-Cacna1c)F1 f 13.85 10.2945 34.1113 0.0
(MA x B6-Cacna1c)F1 m 21.7167 10.2945 41.978 1.4553
(MRL x B6-Cacna1c)F1 f 55.45 10.2945 75.7113 35.1887
(MRL x B6-Cacna1c)F1 m 56.5 11.277 78.6952 34.3048
(NOD x B6-Cacna1c)F1 f 17.25 10.2945 37.5113 0.0
(NOD x B6-Cacna1c)F1 m 26.0 10.2945 46.2613 5.7387
(NON x B6-Cacna1c)F1 f 18.72 11.277 40.9152 0.0
(NON x B6-Cacna1c)F1 m 27.76 11.277 49.9552 5.5648
(NZB x B6-Cacna1c)F1 f 36.4833 10.2945 56.7447 16.222
(NZB x B6-Cacna1c)F1 m 27.54 11.277 49.7352 5.3448
(NZW x B6-Cacna1c)F1 f 44.075 12.6081 68.89 19.26
(NZW x B6-Cacna1c)F1 m 136.3 11.277 158.4952 114.1048
(PL x B6-Cacna1c)F1 f 14.275 12.6081 39.09 0.0
(PL x B6-Cacna1c)F1 m 25.2167 10.2945 45.478 4.9553
(RIII x B6-Cacna1c)F1 f 89.8 10.2945 110.0613 69.5387
(RIII x B6-Cacna1c)F1 m 113.6833 10.2945 133.9447 93.422
(SEA x B6-Cacna1c)F1 f 38.3 10.2945 58.5613 18.0387
(SEA x B6-Cacna1c)F1 m 27.9167 10.2945 48.178 7.6553
(SJL x B6-Cacna1c)F1 f 18.7 10.2945 38.9613 0.0
(SJL x B6-Cacna1c)F1 m 56.4833 10.2945 76.7447 36.222
(SM x B6-Cacna1c)F1 f 45.18 11.277 67.3752 22.9848
(SM x B6-Cacna1c)F1 m 107.9167 10.2945 128.178 87.6553
(SWR x B6-Cacna1c)F1 f 17.9167 10.2945 38.178 0.0
(SWR x B6-Cacna1c)F1 m 49.0 14.5586 77.6539 20.3461


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Cacna1c)F1 both 80.06 7.3825 94.5902 65.5298
(AJ x B6-Cacna1c)F1 both 24.25 7.2793 38.5769 9.9231
(AKR x B6-Cacna1c)F1 both 19.39 7.9741 35.0844 3.6956
(B6 x B6-Cacna1c)F1 both 25.9133 4.6038 34.9745 16.8522
(BALB x B6-Cacna1c)F1 both 14.8083 7.2793 29.1353 0.4814
(BLKS x B6-Cacna1c)F1 both 25.6683 7.6346 40.6945 10.6421
(BTBR x B6-Cacna1c)F1 both 62.0167 7.0145 75.8224 48.2109
(BUB x B6-Cacna1c)F1 both 29.76 7.9741 45.4544 14.0656
(C3H x B6-Cacna1c)F1 both 67.615 7.6346 82.6412 52.5888
(C58 x B6-Cacna1c)F1 both 17.4167 7.2793 31.7436 3.0897
(CBA x B6-Cacna1c)F1 both 71.4125 8.9153 88.9593 53.8657
(DBA x B6-Cacna1c)F1 both 17.8483 7.6346 32.8745 2.8221
(DDY x B6-Cacna1c)F1 both 43.95 7.9741 59.6444 28.2556
(FVB x B6-Cacna1c)F1 both 54.9583 7.2793 69.2853 40.6314
(ILN x B6-Cacna1c)F1 both 80.46 7.6346 95.4862 65.4338
(KK x B6-Cacna1c)F1 both 69.7167 7.2793 84.0436 55.3897
(LG x B6-Cacna1c)F1 both 48.35 7.2793 62.6769 34.0231
(LP x B6-Cacna1c)F1 both 8.4 7.9741 24.0944 0.0
(MA x B6-Cacna1c)F1 both 17.7833 7.2793 32.1103 3.4564
(MRL x B6-Cacna1c)F1 both 55.975 7.6346 71.0012 40.9488
(NOD x B6-Cacna1c)F1 both 21.625 7.2793 35.9519 7.2981
(NON x B6-Cacna1c)F1 both 23.24 7.9741 38.9344 7.5456
(NZB x B6-Cacna1c)F1 both 32.0117 7.6346 47.0379 16.9855
(NZW x B6-Cacna1c)F1 both 90.1875 8.4578 106.8339 73.5411
(PL x B6-Cacna1c)F1 both 19.7458 8.1385 35.7638 3.7278
(RIII x B6-Cacna1c)F1 both 101.7417 7.2793 116.0686 87.4147
(SEA x B6-Cacna1c)F1 both 33.1083 7.2793 47.4353 18.7814
(SJL x B6-Cacna1c)F1 both 37.5917 7.2793 51.9186 23.2647
(SM x B6-Cacna1c)F1 both 76.5483 7.6346 91.5745 61.5221
(SWR x B6-Cacna1c)F1 both 33.4583 8.9153 51.0052 15.9115