Project measure / variable:   Palmer4   immobility

ID, description, units MPD:59331   immobility   duration of immobility   [s]  
Data set, strains Palmer4   F1 Cacna1c   30 strains     sex: both     age: 7-14wks
Procedure forced swim test
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  STRAIN COMPARISON PLOT
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Palmer4 - duration of immobility

(LP x B6-Cacna1c)F1(MA x B6-Cacna1c)F1(B6 x B6-Cacna1c)F1(ILN x B6-Cacna1c)F1(129S x B6-Cacna1c)F1(NON x B6-Cacna1c)F1(DBA x B6-Cacna1c)F1(BUB x B6-Cacna1c)F1(DDY x B6-Cacna1c)F1(BALB x B6-Cacna1c)F1(FVB x B6-Cacna1c)F1(AJ x B6-Cacna1c)F1(LG x B6-Cacna1c)F1(AKR x B6-Cacna1c)F1(BTBR x B6-Cacna1c)F1(NZW x B6-Cacna1c)F1(KK x B6-Cacna1c)F1(MRL x B6-Cacna1c)F1(SM x B6-Cacna1c)F1(BLKS x B6-Cacna1c)F1(NOD x B6-Cacna1c)F1(PL x B6-Cacna1c)F1(RIII x B6-Cacna1c)F1(SJL x B6-Cacna1c)F1(C58 x B6-Cacna1c)F1(SEA x B6-Cacna1c)F1(C3H x B6-Cacna1c)F1(SWR x B6-Cacna1c)F1(NZB x B6-Cacna1c)F1(CBA x B6-Cacna1c)F1 s 020406080100120140160180femalemale


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means27.2   s 23.3   s
Median of the strain means22.8   s 18.5   s
SD of the strain means± 20.2 ± 19.7
Coefficient of variation (CV)0.740 0.845
Min–max range of strain means0.483   –   72.4   s 1.80   –   74.5   s
Mean sample size per strain5.3   mice 5.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 716.2823 716.2823 0.8601 0.3545
strain 29 112027.2866 3863.0099 4.6388 < 0.0001
sex:strain 29 25002.8407 862.1669 1.0353 0.4205
Residuals 275 229008.5104 832.7582


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
(129S x B6-Cacna1c)F1 f 59.3 48.4   7 18.3 0.816 13.5, 123.0 1.59
(129S x B6-Cacna1c)F1 m 36.5 33.5   3 19.3 0.917 13.4, 74.9 0.67
(AJ x B6-Cacna1c)F1 f 14.6 15.1   6 6.18 1.04 1.2, 35.7 -0.63
(AJ x B6-Cacna1c)F1 m 38.2 36.7   6 15.0 0.962 5.3, 98.4 0.76
(AKR x B6-Cacna1c)F1 f 25.5 24.4   5 10.9 0.958 5.7, 53.9 -0.09
(AKR x B6-Cacna1c)F1 m 21.6 25.4   5 11.4 1.18 0.9, 58.1 -0.09
(B6 x B6-Cacna1c)F1 f 48.9 34.4   14 9.2 0.704 9.2, 121.0 1.07
(B6 x B6-Cacna1c)F1 m 60.4 45.2   15 11.7 0.748 6.5, 152.0 1.89
(BALB x B6-Cacna1c)F1 f 46.3 38.5   6 15.7 0.831 14.0, 118.0 0.95
(BALB x B6-Cacna1c)F1 m 18.8 13.1   6 5.35 0.695 6.7, 39.6 -0.23
(BLKS x B6-Cacna1c)F1 f 12.4 24.9   6 10.2 2.0 0.1, 63.0 -0.74
(BLKS x B6-Cacna1c)F1 m 21.4 27.5   6 11.2 1.29 0.5, 74.4 -0.1
(BTBR x B6-Cacna1c)F1 f 27.9 24.6   7 9.31 0.884 1.0, 76.4 0.03
(BTBR x B6-Cacna1c)F1 m 15.9 18.2   6 7.43 1.15 0.6, 51.7 -0.38
(BUB x B6-Cacna1c)F1 f 54.4 29.5   5 13.2 0.543 22.7, 89.6 1.35
(BUB x B6-Cacna1c)F1 m 18.3 13.4   5 6.01 0.734 0.5, 37.5 -0.25
(C3H x B6-Cacna1c)F1 f 3.62 2.76   6 1.13 0.763 0.4, 7.1 -1.17
(C3H x B6-Cacna1c)F1 m 4.76 1.96   5 0.876 0.412 3.3, 7.1 -0.94
(C58 x B6-Cacna1c)F1 f 0.483 1.04   6 0.426 2.16 -1.33
(C58 x B6-Cacna1c)F1 m 11.8 13.7   6 5.61 1.17 -0.58
(CBA x B6-Cacna1c)F1 f 2.4 0.265   3 0.153 0.11 2.2, 2.7 -1.23
(CBA x B6-Cacna1c)F1 m 3.12 2.57   5 1.15 0.823 1.3, 7.6 -1.02
(DBA x B6-Cacna1c)F1 f 34.1 26.8   5 12.0 0.784 12.7, 78.5 0.34
(DBA x B6-Cacna1c)F1 m 44.9 40.1   6 16.4 0.892 12.4, 112.0 1.1
(DDY x B6-Cacna1c)F1 f 56.4 54.1   5 24.2 0.959 3.0, 132.0 1.45
(DDY x B6-Cacna1c)F1 m 16.3 19.9   5 8.88 1.22 0.2, 47.1 -0.35
(FVB x B6-Cacna1c)F1 f 26.1 28.9   6 11.8 1.1 3.4, 77.5 -0.06
(FVB x B6-Cacna1c)F1 m 31.8 42.6   6 17.4 1.34 0.5, 110.0 0.43
(ILN x B6-Cacna1c)F1 f 72.4 65.0   5 29.1 0.898 21.3, 174.0 2.24
(ILN x B6-Cacna1c)F1 m 31.4 10.0   6 4.09 0.319 23.9, 45.6 0.41
(KK x B6-Cacna1c)F1 f 20.9 20.7   4 10.4 0.993 1.1, 48.5 -0.31
(KK x B6-Cacna1c)F1 m 18.7 20.0   6 8.15 1.07 1.3, 54.8 -0.23
(LG x B6-Cacna1c)F1 f 31.9 29.2   6 11.9 0.913 2.2, 81.7 0.23
(LG x B6-Cacna1c)F1 m 17.1 16.8   6 6.85 0.98 4.9, 47.2 -0.31
(LP x B6-Cacna1c)F1 f 52.9 47.7   5 21.3 0.902 6.2, 120.0 1.27
(LP x B6-Cacna1c)F1 m 73.7 58.8   5 26.3 0.798 8.3, 131.0 2.56
(MA x B6-Cacna1c)F1 f 42.5 47.3   5 21.2 1.11 9.5, 119.0 0.76
(MA x B6-Cacna1c)F1 m 74.5 40.1   6 16.4 0.538 18.2, 122.0 2.6
(MRL x B6-Cacna1c)F1 f 15.8 20.7   6 8.46 1.31 3.0, 56.8 -0.57
(MRL x B6-Cacna1c)F1 m 22.8 15.6   5 6.97 0.683 1.6, 45.6 -0.02
(NOD x B6-Cacna1c)F1 f 9.63 14.9   6 6.1 1.55 -0.87
(NOD x B6-Cacna1c)F1 m 14.1 13.2   6 5.37 0.936 0.2, 35.1 -0.47
(NON x B6-Cacna1c)F1 f 52.2 24.0   4 12.0 0.46 26.2, 75.0 1.24
(NON x B6-Cacna1c)F1 m 39.6 25.5   6 10.4 0.645 15.6, 66.4 0.83
(NZB x B6-Cacna1c)F1 f 1.46 1.7   5 0.759 1.16 0.1, 4.3 -1.28
(NZB x B6-Cacna1c)F1 m 6.62 6.69   5 2.99 1.01 0.7, 16.2 -0.85
(NZW x B6-Cacna1c)F1 f 22.5 28.7   5 12.8 1.27 1.2, 71.0 -0.23
(NZW x B6-Cacna1c)F1 m 20.5 24.4   4 12.2 1.19 1.9, 56.1 -0.14
(PL x B6-Cacna1c)F1 f 14.3 15.0   5 6.73 1.05 0.8, 35.2 -0.64
(PL x B6-Cacna1c)F1 m 8.06 12.8   5 5.72 1.59 1.8, 30.9 -0.77
(RIII x B6-Cacna1c)F1 f 14.1 27.4   6 11.2 1.94 -0.65
(RIII x B6-Cacna1c)F1 m 5.23 3.52   6 1.44 0.673 0.3, 9.5 -0.92
(SEA x B6-Cacna1c)F1 f 8.03 7.44   6 3.04 0.926 0.3, 18.3 -0.95
(SEA x B6-Cacna1c)F1 m 2.53 2.5   6 1.02 0.988 0.1, 6.8 -1.05
(SJL x B6-Cacna1c)F1 f 16.5 25.4   5 11.3 1.54 1.5, 61.5 -0.53
(SJL x B6-Cacna1c)F1 m 2.68 3.73   6 1.52 1.39 0.2, 9.9 -1.05
(SM x B6-Cacna1c)F1 f 23.0 30.1   3 17.4 1.31 4.9, 57.7 -0.21
(SM x B6-Cacna1c)F1 m 15.2 14.5   5 6.47 0.954 1.0, 37.0 -0.41
(SWR x B6-Cacna1c)F1 f 6.4 8.06   2   5.7 1.26 0.7, 12.1 -1.03
(SWR x B6-Cacna1c)F1 m 1.8 1.84   2   1.3 1.02 0.5, 3.1 -1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Cacna1c)F1 f 59.3429 10.9071 80.8149 37.8708
(129S x B6-Cacna1c)F1 m 36.5 16.6609 69.2991 3.7009
(AJ x B6-Cacna1c)F1 f 14.55 11.781 37.7425 0.0
(AJ x B6-Cacna1c)F1 m 38.1833 11.781 61.3758 14.9908
(AKR x B6-Cacna1c)F1 f 25.52 12.9055 50.9261 0.1139
(AKR x B6-Cacna1c)F1 m 21.6 12.9055 47.0061 0.0
(B6 x B6-Cacna1c)F1 f 48.9286 7.7125 64.1116 33.7455
(B6 x B6-Cacna1c)F1 m 60.4067 7.451 75.0749 45.7384
(BALB x B6-Cacna1c)F1 f 46.2833 11.781 69.4758 23.0908
(BALB x B6-Cacna1c)F1 m 18.85 11.781 42.0425 0.0
(BLKS x B6-Cacna1c)F1 f 12.4167 11.781 35.6092 0.0
(BLKS x B6-Cacna1c)F1 m 21.4167 11.781 44.6092 0.0
(BTBR x B6-Cacna1c)F1 f 27.8571 10.9071 49.3292 6.3851
(BTBR x B6-Cacna1c)F1 m 15.8833 11.781 39.0758 0.0
(BUB x B6-Cacna1c)F1 f 54.42 12.9055 79.8261 29.0139
(BUB x B6-Cacna1c)F1 m 18.32 12.9055 43.7261 0.0
(C3H x B6-Cacna1c)F1 f 3.6167 11.781 26.8092 0.0
(C3H x B6-Cacna1c)F1 m 4.76 12.9055 30.1661 0.0
(C58 x B6-Cacna1c)F1 f 0.4833 11.781 23.6758 0.0
(C58 x B6-Cacna1c)F1 m 11.7667 11.781 34.9592 0.0
(CBA x B6-Cacna1c)F1 f 2.4 16.6609 35.1991 0.0
(CBA x B6-Cacna1c)F1 m 3.12 12.9055 28.5261 0.0
(DBA x B6-Cacna1c)F1 f 34.12 12.9055 59.5261 8.7139
(DBA x B6-Cacna1c)F1 m 44.9167 11.781 68.1092 21.7242
(DDY x B6-Cacna1c)F1 f 56.38 12.9055 81.7861 30.9739
(DDY x B6-Cacna1c)F1 m 16.34 12.9055 41.7461 0.0
(FVB x B6-Cacna1c)F1 f 26.1333 11.781 49.3258 2.9408
(FVB x B6-Cacna1c)F1 m 31.7667 11.781 54.9592 8.5742
(ILN x B6-Cacna1c)F1 f 72.4 12.9055 97.8061 46.9939
(ILN x B6-Cacna1c)F1 m 31.4167 11.781 54.6092 8.2242
(KK x B6-Cacna1c)F1 f 20.875 14.4288 49.2799 0.0
(KK x B6-Cacna1c)F1 m 18.6833 11.781 41.8758 0.0
(LG x B6-Cacna1c)F1 f 31.9333 11.781 55.1258 8.7408
(LG x B6-Cacna1c)F1 m 17.1167 11.781 40.3092 0.0
(LP x B6-Cacna1c)F1 f 52.88 12.9055 78.2861 27.4739
(LP x B6-Cacna1c)F1 m 73.7 12.9055 99.1061 48.2939
(MA x B6-Cacna1c)F1 f 42.54 12.9055 67.9461 17.1339
(MA x B6-Cacna1c)F1 m 74.5333 11.781 97.7258 51.3408
(MRL x B6-Cacna1c)F1 f 15.8 11.781 38.9925 0.0
(MRL x B6-Cacna1c)F1 m 22.84 12.9055 48.2461 0.0
(NOD x B6-Cacna1c)F1 f 9.6333 11.781 32.8258 0.0
(NOD x B6-Cacna1c)F1 m 14.0667 11.781 37.2592 0.0
(NON x B6-Cacna1c)F1 f 52.175 14.4288 80.5799 23.7701
(NON x B6-Cacna1c)F1 m 39.6167 11.781 62.8092 16.4242
(NZB x B6-Cacna1c)F1 f 1.46 12.9055 26.8661 0.0
(NZB x B6-Cacna1c)F1 m 6.62 12.9055 32.0261 0.0
(NZW x B6-Cacna1c)F1 f 22.54 12.9055 47.9461 0.0
(NZW x B6-Cacna1c)F1 m 20.475 14.4288 48.8799 0.0
(PL x B6-Cacna1c)F1 f 14.3 12.9055 39.7061 0.0
(PL x B6-Cacna1c)F1 m 8.06 12.9055 33.4661 0.0
(RIII x B6-Cacna1c)F1 f 14.0667 11.781 37.2592 0.0
(RIII x B6-Cacna1c)F1 m 5.2333 11.781 28.4258 0.0
(SEA x B6-Cacna1c)F1 f 8.0333 11.781 31.2258 0.0
(SEA x B6-Cacna1c)F1 m 2.5333 11.781 25.7258 0.0
(SJL x B6-Cacna1c)F1 f 16.48 12.9055 41.8861 0.0
(SJL x B6-Cacna1c)F1 m 2.6833 11.781 25.8758 0.0
(SM x B6-Cacna1c)F1 f 22.9667 16.6609 55.7658 0.0
(SM x B6-Cacna1c)F1 m 15.18 12.9055 40.5861 0.0
(SWR x B6-Cacna1c)F1 f 6.4 20.4054 46.5706 0.0
(SWR x B6-Cacna1c)F1 m 1.8 20.4054 41.9706 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Cacna1c)F1 both 47.9214 9.9568 67.5227 28.3202
(AJ x B6-Cacna1c)F1 both 26.3667 8.3305 42.7662 9.9671
(AKR x B6-Cacna1c)F1 both 23.56 9.1256 41.5248 5.5952
(B6 x B6-Cacna1c)F1 both 54.6676 5.3619 65.2232 44.112
(BALB x B6-Cacna1c)F1 both 32.5667 8.3305 48.9662 16.1671
(BLKS x B6-Cacna1c)F1 both 16.9167 8.3305 33.3162 0.5171
(BTBR x B6-Cacna1c)F1 both 21.8702 8.0274 37.6733 6.0672
(BUB x B6-Cacna1c)F1 both 36.37 9.1256 54.3348 18.4052
(C3H x B6-Cacna1c)F1 both 4.1883 8.7371 21.3883 0.0
(C58 x B6-Cacna1c)F1 both 6.125 8.3305 22.5246 0.0
(CBA x B6-Cacna1c)F1 both 2.76 10.5373 23.504 0.0
(DBA x B6-Cacna1c)F1 both 39.5183 8.7371 56.7183 22.3183
(DDY x B6-Cacna1c)F1 both 36.36 9.1256 54.3248 18.3952
(FVB x B6-Cacna1c)F1 both 28.95 8.3305 45.3496 12.5504
(ILN x B6-Cacna1c)F1 both 51.9083 8.7371 69.1083 34.7083
(KK x B6-Cacna1c)F1 both 19.7792 9.3137 38.1144 1.4439
(LG x B6-Cacna1c)F1 both 24.525 8.3305 40.9246 8.1254
(LP x B6-Cacna1c)F1 both 63.29 9.1256 81.2548 45.3252
(MA x B6-Cacna1c)F1 both 58.5367 8.7371 75.7367 41.3367
(MRL x B6-Cacna1c)F1 both 19.32 8.7371 36.52 2.12
(NOD x B6-Cacna1c)F1 both 11.85 8.3305 28.2496 0.0
(NON x B6-Cacna1c)F1 both 45.8958 9.3137 64.2311 27.5606
(NZB x B6-Cacna1c)F1 both 4.04 9.1256 22.0048 0.0
(NZW x B6-Cacna1c)F1 both 21.5075 9.6791 40.5621 2.4529
(PL x B6-Cacna1c)F1 both 11.18 9.1256 29.1448 0.0
(RIII x B6-Cacna1c)F1 both 9.65 8.3305 26.0496 0.0
(SEA x B6-Cacna1c)F1 both 5.2833 8.3305 21.6829 0.0
(SJL x B6-Cacna1c)F1 both 9.5817 8.7371 26.7817 0.0
(SM x B6-Cacna1c)F1 both 19.0733 10.5373 39.8173 0.0
(SWR x B6-Cacna1c)F1 both 4.1 14.4288 32.5049 0.0




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA