Project measure / variable:   Palmer4   distance_d3_d2

ID, description, units MPD:59324   distance_d3_d2   total distance traveled on day 3 (methamphetamine) minus total distance traveled on day 2 (saline)   [cm]  
methamphetamine study
Data set, strains Palmer4   F1 Cacna1c   30 strains     sex: both     age: 7-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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Palmer4 - total distance traveled on day 3 (methamphetamine) minus total distance traveled on day 2 (saline)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means9204   cm 8841   cm
Median of the strain means9050   cm 8304   cm
SD of the strain means± 4534 ± 3660
Coefficient of variation (CV)0.493 0.414
Min–max range of strain means643   –   17543   cm 2791   –   16302   cm
Mean sample size per strain5.6   mice 5.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 30474345.1155 30474345.1155 1.5367 0.2161
strain 29 4805314718.413 165700507.5315 8.3555 < 0.0001
sex:strain 29 729942836.5952 25170442.6412 1.2692 0.1668
Residuals 290 5751049477.0905 19831205.0934


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(129S x B6-Cacna1c)F1 f 643.0 1309.0   7 495.0 2.04 -525.0, 3091.0 -1.89
(129S x B6-Cacna1c)F1 m 4196.0 5700.0   5 2549.0 1.36 -248.0, 14132.0 -1.27
(AJ x B6-Cacna1c)F1 f 4357.0 4954.0   6 2023.0 1.14 -1797.0, 10929.0 -1.07
(AJ x B6-Cacna1c)F1 m 2791.0 4901.0   6 2001.0 1.76 -1399.0, 12097.0 -1.65
(AKR x B6-Cacna1c)F1 f 15410.0 2223.0   5 994.0 0.144 13474.0, 19068.0 1.37
(AKR x B6-Cacna1c)F1 m 13362.0 6032.0   5 2697.0 0.451 4825.0, 21184.0 1.24
(B6 x B6-Cacna1c)F1 f 13331.0 6202.0   14 1657.0 0.465 3814.0, 24681.0 0.91
(B6 x B6-Cacna1c)F1 m 9553.0 4746.0   15 1226.0 0.497 1657.0, 17922.0 0.19
(BALB x B6-Cacna1c)F1 f 6922.0 2914.0   4 1457.0 0.421 4735.0, 11203.0 -0.5
(BALB x B6-Cacna1c)F1 m 7623.0 3407.0   6 1391.0 0.447 1817.0, 12128.0 -0.33
(BLKS x B6-Cacna1c)F1 f 2530.0 2203.0   6 899.0 0.871 -1397.0, 5307.0 -1.47
(BLKS x B6-Cacna1c)F1 m 4860.0 5390.0   6 2201.0 1.11 -2282.0, 12071.0 -1.09
(BTBR x B6-Cacna1c)F1 f 4887.0 2657.0   7 1004.0 0.544 1351.0, 9366.0 -0.95
(BTBR x B6-Cacna1c)F1 m 4093.0 3214.0   6 1312.0 0.785 -731.0, 6814.0 -1.3
(BUB x B6-Cacna1c)F1 f 7145.0 6428.0   4 3214.0 0.9 -130.0, 14473.0 -0.45
(BUB x B6-Cacna1c)F1 m 7870.0 5058.0   5 2262.0 0.643 2094.0, 12968.0 -0.27
(C3H x B6-Cacna1c)F1 f 12721.0 5296.0   6 2162.0 0.416 7805.0, 21537.0 0.78
(C3H x B6-Cacna1c)F1 m 7173.0 5981.0   5 2675.0 0.834 -1197.0, 14472.0 -0.46
(C58 x B6-Cacna1c)F1 f 17543.0 4246.0   5 1899.0 0.242 10058.0, 20193.0 1.84
(C58 x B6-Cacna1c)F1 m 14954.0 7146.0   6 2917.0 0.478 8982.0, 25814.0 1.67
(CBA x B6-Cacna1c)F1 f 9762.0 2257.0   5 1010.0 0.231 7590.0, 13420.0 0.12
(CBA x B6-Cacna1c)F1 m 8425.0 4842.0   5 2165.0 0.575 1663.0, 13730.0 -0.11
(DBA x B6-Cacna1c)F1 f 3003.0 1263.0   5 565.0 0.421 1753.0, 5010.0 -1.37
(DBA x B6-Cacna1c)F1 m 5741.0 3924.0   6 1602.0 0.683 1308.0, 12394.0 -0.85
(DDY x B6-Cacna1c)F1 f 11160.0 6240.0   6 2547.0 0.559 584.0, 18251.0 0.43
(DDY x B6-Cacna1c)F1 m 11267.0 4540.0   4 2270.0 0.403 7662.0, 17686.0 0.66
(FVB x B6-Cacna1c)F1 f 10289.0 7050.0   6 2878.0 0.685 2188.0, 22742.0 0.24
(FVB x B6-Cacna1c)F1 m 12798.0 5527.0   6 2256.0 0.432 4919.0, 18362.0 1.08
(ILN x B6-Cacna1c)F1 f 6545.0 4641.0   6 1895.0 0.709 -32.0, 11308.0 -0.59
(ILN x B6-Cacna1c)F1 m 5186.0 2571.0   6 1050.0 0.496 2762.0, 9483.0 -1.0
(KK x B6-Cacna1c)F1 f 7781.0 2377.0   6 970.0 0.305 5581.0, 12272.0 -0.31
(KK x B6-Cacna1c)F1 m 6345.0 3491.0   6 1425.0 0.55 3856.0, 13050.0 -0.68
(LG x B6-Cacna1c)F1 f 7983.0 4124.0   6 1684.0 0.517 2393.0, 13709.0 -0.27
(LG x B6-Cacna1c)F1 m 6056.0 5722.0   6 2336.0 0.945 -798.0, 14023.0 -0.76
(LP x B6-Cacna1c)F1 f 2699.0 2932.0   5 1311.0 1.09 -805.0, 7143.0 -1.43
(LP x B6-Cacna1c)F1 m 5797.0 4252.0   5 1902.0 0.734 1675.0, 12421.0 -0.83
(MA x B6-Cacna1c)F1 f 7025.0 5038.0   5 2253.0 0.717 -428.0, 13394.0 -0.48
(MA x B6-Cacna1c)F1 m 6011.0 2211.0   6 903.0 0.368 2788.0, 8956.0 -0.77
(MRL x B6-Cacna1c)F1 f 9864.0 1518.0   6 620.0 0.154 8621.0, 12761.0 0.15
(MRL x B6-Cacna1c)F1 m 8182.0 1079.0   5 483.0 0.132 7071.0, 9904.0 -0.18
(NOD x B6-Cacna1c)F1 f 9875.0 5960.0   6 2433.0 0.604 4400.0, 20549.0 0.15
(NOD x B6-Cacna1c)F1 m 10172.0 2222.0   6 907.0 0.218 6814.0, 12775.0 0.36
(NON x B6-Cacna1c)F1 f 7785.0 2389.0   5 1068.0 0.307 4141.0, 9848.0 -0.31
(NON x B6-Cacna1c)F1 m 11108.0 4451.0   6 1817.0 0.401 5181.0, 16767.0 0.62
(NZB x B6-Cacna1c)F1 f 8338.0 5064.0   6 2067.0 0.607 457.0, 13938.0 -0.19
(NZB x B6-Cacna1c)F1 m 12974.0 3668.0   4 1834.0 0.283 9643.0, 17535.0 1.13
(NZW x B6-Cacna1c)F1 f 4730.0 2869.0   5 1283.0 0.607 -213.0, 6716.0 -0.99
(NZW x B6-Cacna1c)F1 m 4285.0 1959.0   5 876.0 0.457 1796.0, 7276.0 -1.24
(PL x B6-Cacna1c)F1 f 16049.0 2428.0   5 1086.0 0.151 13701.0, 19298.0 1.51
(PL x B6-Cacna1c)F1 m 8731.0 2429.0   6 992.0 0.278 4218.0, 10643.0 -0.03
(RIII x B6-Cacna1c)F1 f 14471.0 3346.0   6 1366.0 0.231 8232.0, 17363.0 1.16
(RIII x B6-Cacna1c)F1 m 12814.0 3719.0   6 1518.0 0.29 9045.0, 18073.0 1.09
(SEA x B6-Cacna1c)F1 f 16451.0 6012.0   6 2454.0 0.365 6343.0, 23660.0 1.6
(SEA x B6-Cacna1c)F1 m 12794.0 4490.0   6 1833.0 0.351 5574.0, 19575.0 1.08
(SJL x B6-Cacna1c)F1 f 11189.0 6108.0   6 2494.0 0.546 2374.0, 19164.0 0.44
(SJL x B6-Cacna1c)F1 m 12812.0 5350.0   6 2184.0 0.418 6082.0, 18544.0 1.08
(SM x B6-Cacna1c)F1 f 14701.0 3171.0   5 1418.0 0.216 11288.0, 19129.0 1.21
(SM x B6-Cacna1c)F1 m 10950.0 5968.0   6 2437.0 0.545 2757.0, 18919.0 0.58
(SWR x B6-Cacna1c)F1 f 10923.0 3736.0   6 1525.0 0.342 4793.0, 14632.0 0.38
(SWR x B6-Cacna1c)F1 m 16302.0 942.0   3 544.0 0.0578 15417.0, 17292.0 2.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Cacna1c)F1 f 642.5714 1683.1605 3955.3307 0.0
(129S x B6-Cacna1c)F1 m 4196.2 1991.5424 8115.9097 276.4903
(AJ x B6-Cacna1c)F1 f 4356.6667 1818.0211 7934.8557 778.4777
(AJ x B6-Cacna1c)F1 m 2791.1667 1818.0211 6369.3557 0.0
(AKR x B6-Cacna1c)F1 f 15409.8 1991.5424 19329.5097 11490.0903
(AKR x B6-Cacna1c)F1 m 13361.8 1991.5424 17281.5097 9442.0903
(B6 x B6-Cacna1c)F1 f 13331.1429 1190.1742 15673.6174 10988.6683
(B6 x B6-Cacna1c)F1 m 9552.5333 1149.8175 11815.5788 7289.4879
(BALB x B6-Cacna1c)F1 f 6921.5 2226.6121 11303.8686 2539.1314
(BALB x B6-Cacna1c)F1 m 7623.3333 1818.0211 11201.5223 4045.1443
(BLKS x B6-Cacna1c)F1 f 2530.5 1818.0211 6108.689 0.0
(BLKS x B6-Cacna1c)F1 m 4860.1667 1818.0211 8438.3557 1281.9777
(BTBR x B6-Cacna1c)F1 f 4886.7143 1683.1605 8199.4736 1573.955
(BTBR x B6-Cacna1c)F1 m 4092.6667 1818.0211 7670.8557 514.4777
(BUB x B6-Cacna1c)F1 f 7145.25 2226.6121 11527.6186 2762.8814
(BUB x B6-Cacna1c)F1 m 7869.6 1991.5424 11789.3097 3949.8903
(C3H x B6-Cacna1c)F1 f 12721.0 1818.0211 16299.189 9142.811
(C3H x B6-Cacna1c)F1 m 7173.2 1991.5424 11092.9097 3253.4903
(C58 x B6-Cacna1c)F1 f 17542.6 1991.5424 21462.3097 13622.8903
(C58 x B6-Cacna1c)F1 m 14954.5 1818.0211 18532.689 11376.311
(CBA x B6-Cacna1c)F1 f 9761.6 1991.5424 13681.3097 5841.8903
(CBA x B6-Cacna1c)F1 m 8424.6 1991.5424 12344.3097 4504.8903
(DBA x B6-Cacna1c)F1 f 3003.4 1991.5424 6923.1097 0.0
(DBA x B6-Cacna1c)F1 m 5741.1667 1818.0211 9319.3557 2162.9777
(DDY x B6-Cacna1c)F1 f 11160.5 1818.0211 14738.689 7582.311
(DDY x B6-Cacna1c)F1 m 11267.25 2226.6121 15649.6186 6884.8814
(FVB x B6-Cacna1c)F1 f 10288.8333 1818.0211 13867.0223 6710.6443
(FVB x B6-Cacna1c)F1 m 12798.3333 1818.0211 16376.5223 9220.1443
(ILN x B6-Cacna1c)F1 f 6545.1667 1818.0211 10123.3557 2966.9777
(ILN x B6-Cacna1c)F1 m 5185.5 1818.0211 8763.689 1607.311
(KK x B6-Cacna1c)F1 f 7781.1667 1818.0211 11359.3557 4202.9777
(KK x B6-Cacna1c)F1 m 6344.6667 1818.0211 9922.8557 2766.4777
(LG x B6-Cacna1c)F1 f 7982.6667 1818.0211 11560.8557 4404.4777
(LG x B6-Cacna1c)F1 m 6056.0 1818.0211 9634.189 2477.811
(LP x B6-Cacna1c)F1 f 2698.8 1991.5424 6618.5097 0.0
(LP x B6-Cacna1c)F1 m 5797.4 1991.5424 9717.1097 1877.6903
(MA x B6-Cacna1c)F1 f 7024.6 1991.5424 10944.3097 3104.8903
(MA x B6-Cacna1c)F1 m 6011.3333 1818.0211 9589.5223 2433.1443
(MRL x B6-Cacna1c)F1 f 9863.6667 1818.0211 13441.8557 6285.4777
(MRL x B6-Cacna1c)F1 m 8182.4 1991.5424 12102.1097 4262.6903
(NOD x B6-Cacna1c)F1 f 9875.0 1818.0211 13453.189 6296.811
(NOD x B6-Cacna1c)F1 m 10172.1667 1818.0211 13750.3557 6593.9777
(NON x B6-Cacna1c)F1 f 7784.8 1991.5424 11704.5097 3865.0903
(NON x B6-Cacna1c)F1 m 11108.1667 1818.0211 14686.3557 7529.9777
(NZB x B6-Cacna1c)F1 f 8337.8333 1818.0211 11916.0223 4759.6443
(NZB x B6-Cacna1c)F1 m 12974.5 2226.6121 17356.8686 8592.1314
(NZW x B6-Cacna1c)F1 f 4730.2 1991.5424 8649.9097 810.4903
(NZW x B6-Cacna1c)F1 m 4284.8 1991.5424 8204.5097 365.0903
(PL x B6-Cacna1c)F1 f 16049.0 1991.5424 19968.7097 12129.2903
(PL x B6-Cacna1c)F1 m 8731.1667 1818.0211 12309.3557 5152.9777
(RIII x B6-Cacna1c)F1 f 14471.0 1818.0211 18049.189 10892.811
(RIII x B6-Cacna1c)F1 m 12813.8333 1818.0211 16392.0223 9235.6443
(SEA x B6-Cacna1c)F1 f 16451.0 1818.0211 20029.189 12872.811
(SEA x B6-Cacna1c)F1 m 12793.6667 1818.0211 16371.8557 9215.4777
(SJL x B6-Cacna1c)F1 f 11188.8333 1818.0211 14767.0223 7610.6443
(SJL x B6-Cacna1c)F1 m 12812.5 1818.0211 16390.689 9234.311
(SM x B6-Cacna1c)F1 f 14701.0 1991.5424 18620.7097 10781.2903
(SM x B6-Cacna1c)F1 m 10949.5 1818.0211 14527.689 7371.311
(SWR x B6-Cacna1c)F1 f 10922.6667 1818.0211 14500.8557 7344.4777
(SWR x B6-Cacna1c)F1 m 16301.6667 2571.0701 21361.9901 11241.3432


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Cacna1c)F1 both 2419.3857 1303.7705 4985.438 0.0
(AJ x B6-Cacna1c)F1 both 3573.9167 1285.5351 6104.0784 1043.755
(AKR x B6-Cacna1c)F1 both 14385.8 1408.2331 17157.4533 11614.1467
(B6 x B6-Cacna1c)F1 both 11441.8381 827.435 13070.3775 9813.2987
(BALB x B6-Cacna1c)F1 both 7272.4167 1437.2719 10101.2235 4443.6099
(BLKS x B6-Cacna1c)F1 both 3695.3333 1285.5351 6225.495 1165.1716
(BTBR x B6-Cacna1c)F1 both 4489.6905 1238.7726 6927.8153 2051.5656
(BUB x B6-Cacna1c)F1 both 7507.425 1493.6568 10447.2073 4567.6427
(C3H x B6-Cacna1c)F1 both 9947.1 1348.2806 12600.756 7293.444
(C58 x B6-Cacna1c)F1 both 16248.55 1348.2806 18902.206 13594.894
(CBA x B6-Cacna1c)F1 both 9093.1 1408.2331 11864.7533 6321.4467
(DBA x B6-Cacna1c)F1 both 4372.2833 1348.2806 7025.9393 1718.6273
(DDY x B6-Cacna1c)F1 both 11213.875 1437.2719 14042.6818 8385.0682
(FVB x B6-Cacna1c)F1 both 11543.5833 1285.5351 14073.745 9013.4216
(ILN x B6-Cacna1c)F1 both 5865.3333 1285.5351 8395.495 3335.1716
(KK x B6-Cacna1c)F1 both 7062.9167 1285.5351 9593.0784 4532.755
(LG x B6-Cacna1c)F1 both 7019.3333 1285.5351 9549.495 4489.1716
(LP x B6-Cacna1c)F1 both 4248.1 1408.2331 7019.7533 1476.4467
(MA x B6-Cacna1c)F1 both 6517.9667 1348.2806 9171.6227 3864.3107
(MRL x B6-Cacna1c)F1 both 9023.0333 1348.2806 11676.6893 6369.3773
(NOD x B6-Cacna1c)F1 both 10023.5833 1285.5351 12553.745 7493.4216
(NON x B6-Cacna1c)F1 both 9446.4833 1348.2806 12100.1393 6792.8273
(NZB x B6-Cacna1c)F1 both 10656.1667 1437.2719 13484.9735 7827.3599
(NZW x B6-Cacna1c)F1 both 4507.5 1408.2331 7279.1533 1735.8467
(PL x B6-Cacna1c)F1 both 12390.0833 1348.2806 15043.7393 9736.4273
(RIII x B6-Cacna1c)F1 both 13642.4167 1285.5351 16172.5784 11112.255
(SEA x B6-Cacna1c)F1 both 14622.3333 1285.5351 17152.495 12092.1716
(SJL x B6-Cacna1c)F1 both 12000.6667 1285.5351 14530.8284 9470.505
(SM x B6-Cacna1c)F1 both 12825.25 1348.2806 15478.906 10171.594
(SWR x B6-Cacna1c)F1 both 13612.1667 1574.4525 16710.9693 10513.3641




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA