Phenotype measure

ID, description, units MPD:59232   PPI   percentage prepulse inhibition (PPI) evoked by 120 dB sound pressure level with 6 dB prepulse stimulus   [%]
Data set, strains Palmer3   F1 Tcf7l2   30 strains     sex: both     age: 7-14wks
Procedure acoustic startle test
Ontology mappings


  STRAIN COMPARISON PLOT
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Palmer3 - percentage prepulse inhibition (PPI) evoked by 120 dB sound pressure level with 6 dB prepulse stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains29 strains
Mean of the strain means43.4   % 47.5   %
Median of the strain means45.6   % 46.6   %
SD of the strain means± 12.4 ± 10.3
Coefficient of variation (CV)0.285 0.217
Min–max range of strain means9.97   –   60.4   % 22.1   –   67.1   %
Mean sample size per strain5.2   mice 4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1576.0702 1576.0702 4.8351 0.0288
strain 28 24284.2025 867.2929 2.6607 < 0.0001
sex:strain 28 9674.3295 345.5118 1.06 0.3891
Residuals 239 77905.3659 325.9639


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(129S x B6-Tcf7l2)F1 f 54.6 7.92   5 3.54 0.145 41.0, 61.4 0.91
(129S x B6-Tcf7l2)F1 m 60.0 18.6   4 9.32 0.311 33.8, 75.2 1.22
(AJ x B6-Tcf7l2)F1 f 36.5 27.7   6 11.3 0.759 -10.5, 63.6 -0.56
(AJ x B6-Tcf7l2)F1 m 50.7 9.54   3 5.51 0.188 43.1, 61.4 0.31
(AKR x B6-Tcf7l2)F1 f 50.5 12.1   4 6.06 0.24 39.8, 65.1 0.58
(B6 x B6-Tcf7l2)F1 f 42.8 20.7   8 7.33 0.485 2.6, 71.8 -0.05
(B6 x B6-Tcf7l2)F1 m 55.2 12.4   9 4.15 0.225 31.6, 72.0 0.75
(BALB x B6-Tcf7l2)F1 f 56.4 10.2   5 4.56 0.181 46.1, 69.4 1.05
(BALB x B6-Tcf7l2)F1 m 45.9 18.1   4 9.07 0.395 26.3, 70.1 -0.15
(BLKS x B6-Tcf7l2)F1 f 49.4 16.7   5 7.48 0.338 28.9, 70.0 0.49
(BLKS x B6-Tcf7l2)F1 m 52.1 18.9   5 8.44 0.362 24.7, 75.1 0.45
(BTBR x B6-Tcf7l2)F1 f 45.2 24.3   6 9.92 0.537 11.7, 79.2 0.15
(BTBR x B6-Tcf7l2)F1 m 55.5 18.6   5 8.3 0.334 31.7, 75.7 0.78
(BUB x B6-Tcf7l2)F1 f 45.8 11.4   5 5.11 0.25 27.7, 56.0 0.2
(BUB x B6-Tcf7l2)F1 m 50.0 14.7   5 6.56 0.293 27.6, 68.3 0.25
(C3H x B6-Tcf7l2)F1 f 58.0 21.3   7 8.06 0.368 14.7, 76.7 1.18
(C3H x B6-Tcf7l2)F1 m 56.2 14.1   4 7.06 0.251 39.4, 72.1 0.85
(C57L x B6-Tcf7l2)F1 f 9.97 18.6   3 10.7 1.86 -1.6, 31.4 -2.7
(C57L x B6-Tcf7l2)F1 m 53.0 16.9   5 7.54 0.318 34.3, 75.8 0.54
(C58 x B6-Tcf7l2)F1 f 45.8 23.4   4 11.7 0.51 22.3, 77.8 0.2
(C58 x B6-Tcf7l2)F1 m 46.4 19.1   3 11.0 0.411 26.9, 65.0 -0.1
(CBA x B6-Tcf7l2)F1 f 60.3 11.0   4 5.51 0.183 47.8, 73.6 1.37
(CBA x B6-Tcf7l2)F1 m 40.8 28.8   6 11.8 0.706 3.8, 80.1 -0.65
(DBA x B6-Tcf7l2)F1 f 32.7 13.8   5 6.19 0.422 10.9, 49.1 -0.86
(DBA x B6-Tcf7l2)F1 m 35.1 17.2   5 7.68 0.489 13.6, 59.2 -1.2
(DDY x B6-Tcf7l2)F1 f 55.1 3.75   5 1.68 0.0679 50.4, 60.2 0.95
(DDY x B6-Tcf7l2)F1 m 66.8 8.47   3 4.89 0.127 58.7, 75.6 1.88
(FVB x B6-Tcf7l2)F1 f 60.4 5.89   4 2.95 0.0975 55.8, 68.2 1.38
(FVB x B6-Tcf7l2)F1 m 61.0 15.8   7 5.97 0.259 42.3, 83.5 1.32
(ILN x B6-Tcf7l2)F1 f 54.1 19.1   4 9.57 0.354 33.6, 76.2 0.87
(ILN x B6-Tcf7l2)F1 m 42.2 12.9   8 4.55 0.305 23.6, 65.1 -0.51
(KK x B6-Tcf7l2)F1 f 34.1 14.4   6 5.9 0.423 16.1, 57.8 -0.75
(KK x B6-Tcf7l2)F1 m 46.6 20.9   2   14.8 0.449 31.8, 61.4 -0.08
(LP x B6-Tcf7l2)F1 f 39.2 26.7   6 10.9 0.681 8.1, 69.1 -0.34
(LP x B6-Tcf7l2)F1 m 31.5 35.7   2   25.2 1.13 6.3, 56.8 -1.55
(MA x B6-Tcf7l2)F1 f 36.0 25.2   5 11.3 0.701 12.0, 76.5 -0.6
(MA x B6-Tcf7l2)F1 m 31.5 12.3   5 5.5 0.39 11.0, 42.8 -1.55
(MRL x B6-Tcf7l2)F1 f 49.2 15.6   4 7.81 0.318 32.8, 66.3 0.47
(MRL x B6-Tcf7l2)F1 m 51.6 14.9   4 7.47 0.29 37.1, 72.1 0.4
(NOD x B6-Tcf7l2)F1 f 25.2 9.46   6 3.86 0.375 12.0, 36.2 -1.47
(NOD x B6-Tcf7l2)F1 m 48.1 14.2   7 5.38 0.296 22.5, 63.6 0.06
(NON x B6-Tcf7l2)F1 f 45.5 18.9   7 7.15 0.416 12.9, 63.1 0.17
(NON x B6-Tcf7l2)F1 m 43.6 15.3   8 5.4 0.35 21.6, 67.3 -0.38
(NZB x B6-Tcf7l2)F1 f 33.1 20.5   8 7.23 0.617 -2.9, 61.3 -0.83
(NZB x B6-Tcf7l2)F1 m 39.7 10.4   8 3.66 0.261 23.7, 52.0 -0.76
(NZW x B6-Tcf7l2)F1 f 43.1 10.9   4 5.44 0.252 29.5, 53.2 -0.02
(NZW x B6-Tcf7l2)F1 m 41.0 9.15   5 4.09 0.223 33.7, 55.6 -0.63
(PL x B6-Tcf7l2)F1 f 16.7 35.6   6 14.5 2.13 -54.8, 40.8 -2.16
(PL x B6-Tcf7l2)F1 m 46.6 13.4   2   9.5 0.288 37.1, 56.1 -0.08
(RIII x B6-Tcf7l2)F1 f 56.0 17.3   6 7.05 0.309 35.4, 77.6 1.02
(RIII x B6-Tcf7l2)F1 m 67.1 22.4   4 11.2 0.333 43.0, 86.5 1.91
(SEA x B6-Tcf7l2)F1 f 47.4 23.4   4 11.7 0.493 15.4, 70.1 0.33
(SEA x B6-Tcf7l2)F1 m 51.3 16.3   7 6.16 0.318 25.0, 74.1 0.37
(SJL x B6-Tcf7l2)F1 f 45.7 20.2   6 8.23 0.442 23.6, 71.4 0.19
(SJL x B6-Tcf7l2)F1 m 44.5 14.3   4 7.17 0.322 23.1, 53.8 -0.29
(SM x B6-Tcf7l2)F1 f 42.7 20.0   5 8.93 0.468 17.4, 70.0 -0.05
(SM x B6-Tcf7l2)F1 m 40.6 15.1   5 6.76 0.372 14.4, 50.3 -0.67
(SWR x B6-Tcf7l2)F1 f 29.6 6.47   5 2.89 0.218 23.6, 39.2 -1.11
(SWR x B6-Tcf7l2)F1 m 22.1 25.1   4 12.6 1.14 -12.3, 48.1 -2.47


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Tcf7l2)F1 f 54.62 8.0742 70.5257 38.7143
(129S x B6-Tcf7l2)F1 m 59.95 9.0272 77.7331 42.1669
(AJ x B6-Tcf7l2)F1 f 36.5 7.3707 51.0198 21.9802
(AJ x B6-Tcf7l2)F1 m 50.7 10.4238 71.2342 30.1658
(B6 x B6-Tcf7l2)F1 f 42.7625 6.3832 55.3371 30.1879
(B6 x B6-Tcf7l2)F1 m 55.1778 6.0182 67.0332 43.3224
(BALB x B6-Tcf7l2)F1 f 56.36 8.0742 72.2657 40.4543
(BALB x B6-Tcf7l2)F1 m 45.875 9.0272 63.6581 28.0919
(BLKS x B6-Tcf7l2)F1 f 49.42 8.0742 65.3257 33.5143
(BLKS x B6-Tcf7l2)F1 m 52.14 8.0742 68.0457 36.2343
(BTBR x B6-Tcf7l2)F1 f 45.2333 7.3707 59.7532 30.7135
(BTBR x B6-Tcf7l2)F1 m 55.52 8.0742 71.4257 39.6143
(BUB x B6-Tcf7l2)F1 f 45.76 8.0742 61.6657 29.8543
(BUB x B6-Tcf7l2)F1 m 50.04 8.0742 65.9457 34.1343
(C3H x B6-Tcf7l2)F1 f 57.9857 6.8239 71.4285 44.543
(C3H x B6-Tcf7l2)F1 m 56.225 9.0272 74.0081 38.4419
(C57L x B6-Tcf7l2)F1 f 9.9667 10.4238 30.5008 0.0
(C57L x B6-Tcf7l2)F1 m 53.04 8.0742 68.9457 37.1343
(C58 x B6-Tcf7l2)F1 f 45.85 9.0272 63.6331 28.0669
(C58 x B6-Tcf7l2)F1 m 46.3667 10.4238 66.9008 25.8325
(CBA x B6-Tcf7l2)F1 f 60.325 9.0272 78.1081 42.5419
(CBA x B6-Tcf7l2)F1 m 40.8 7.3707 55.3198 26.2802
(DBA x B6-Tcf7l2)F1 f 32.74 8.0742 48.6457 16.8343
(DBA x B6-Tcf7l2)F1 m 35.08 8.0742 50.9857 19.1743
(DDY x B6-Tcf7l2)F1 f 55.14 8.0742 71.0457 39.2343
(DDY x B6-Tcf7l2)F1 m 66.8 10.4238 87.3342 46.2658
(FVB x B6-Tcf7l2)F1 f 60.425 9.0272 78.2081 42.6419
(FVB x B6-Tcf7l2)F1 m 61.0286 6.8239 74.4713 47.5858
(ILN x B6-Tcf7l2)F1 f 54.1 9.0272 71.8831 36.3169
(ILN x B6-Tcf7l2)F1 m 42.2 6.3832 54.7746 29.6254
(KK x B6-Tcf7l2)F1 f 34.1333 7.3707 48.6532 19.6135
(KK x B6-Tcf7l2)F1 m 46.6 12.7664 71.7491 21.4509
(LP x B6-Tcf7l2)F1 f 39.1833 7.3707 53.7032 24.6635
(LP x B6-Tcf7l2)F1 m 31.55 12.7664 56.6991 6.4009
(MA x B6-Tcf7l2)F1 f 35.96 8.0742 51.8657 20.0543
(MA x B6-Tcf7l2)F1 m 31.54 8.0742 47.4457 15.6343
(MRL x B6-Tcf7l2)F1 f 49.2 9.0272 66.9831 31.4169
(MRL x B6-Tcf7l2)F1 m 51.575 9.0272 69.3581 33.7919
(NOD x B6-Tcf7l2)F1 f 25.2333 7.3707 39.7532 10.7135
(NOD x B6-Tcf7l2)F1 m 48.1429 6.8239 61.5856 34.7001
(NON x B6-Tcf7l2)F1 f 45.4857 6.8239 58.9285 32.043
(NON x B6-Tcf7l2)F1 m 43.575 6.3832 56.1496 31.0004
(NZB x B6-Tcf7l2)F1 f 33.1375 6.3832 45.7121 20.5629
(NZB x B6-Tcf7l2)F1 m 39.65 6.3832 52.2246 27.0754
(NZW x B6-Tcf7l2)F1 f 43.1 9.0272 60.8831 25.3169
(NZW x B6-Tcf7l2)F1 m 41.04 8.0742 56.9457 25.1343
(PL x B6-Tcf7l2)F1 f 16.6833 7.3707 31.2032 2.1635
(PL x B6-Tcf7l2)F1 m 46.6 12.7664 71.7491 21.4509
(RIII x B6-Tcf7l2)F1 f 55.9833 7.3707 70.5032 41.4635
(RIII x B6-Tcf7l2)F1 m 67.125 9.0272 84.9081 49.3419
(SEA x B6-Tcf7l2)F1 f 47.425 9.0272 65.2081 29.6419
(SEA x B6-Tcf7l2)F1 m 51.3143 6.8239 64.757 37.8715
(SJL x B6-Tcf7l2)F1 f 45.6667 7.3707 60.1865 31.1468
(SJL x B6-Tcf7l2)F1 m 44.5 9.0272 62.2831 26.7169
(SM x B6-Tcf7l2)F1 f 42.68 8.0742 58.5857 26.7743
(SM x B6-Tcf7l2)F1 m 40.64 8.0742 56.5457 24.7343
(SWR x B6-Tcf7l2)F1 f 29.64 8.0742 45.5457 13.7343
(SWR x B6-Tcf7l2)F1 m 22.075 9.0272 39.8581 4.2919


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Tcf7l2)F1 both 57.285 6.0557 69.2143 45.3557
(AJ x B6-Tcf7l2)F1 both 43.6 6.3832 56.1746 31.0254
(B6 x B6-Tcf7l2)F1 both 48.9701 4.3864 57.6112 40.3291
(BALB x B6-Tcf7l2)F1 both 51.1175 6.0557 63.0468 39.1882
(BLKS x B6-Tcf7l2)F1 both 50.78 5.7093 62.027 39.533
(BTBR x B6-Tcf7l2)F1 both 50.3767 5.4663 61.1449 39.6085
(BUB x B6-Tcf7l2)F1 both 47.9 5.7093 59.147 36.653
(C3H x B6-Tcf7l2)F1 both 57.1054 5.6581 68.2515 45.9592
(C57L x B6-Tcf7l2)F1 both 31.5033 6.5926 44.4903 18.5164
(C58 x B6-Tcf7l2)F1 both 46.1083 6.8947 59.6904 32.5263
(CBA x B6-Tcf7l2)F1 both 50.5625 5.8271 62.0414 39.0836
(DBA x B6-Tcf7l2)F1 both 33.91 5.7093 45.157 22.663
(DDY x B6-Tcf7l2)F1 both 60.97 6.5926 73.9569 47.9831
(FVB x B6-Tcf7l2)F1 both 60.7268 5.6581 71.8729 49.5806
(ILN x B6-Tcf7l2)F1 both 48.15 5.528 59.0399 37.2601
(KK x B6-Tcf7l2)F1 both 40.3667 7.3707 54.8865 25.8468
(LP x B6-Tcf7l2)F1 both 35.3667 7.3707 49.8865 20.8468
(MA x B6-Tcf7l2)F1 both 33.75 5.7093 44.997 22.503
(MRL x B6-Tcf7l2)F1 both 50.3875 6.3832 62.9621 37.8129
(NOD x B6-Tcf7l2)F1 both 36.6881 5.0223 46.5817 26.7945
(NON x B6-Tcf7l2)F1 both 44.5304 4.672 53.734 35.3267
(NZB x B6-Tcf7l2)F1 both 36.3938 4.5136 45.2853 27.5022
(NZW x B6-Tcf7l2)F1 both 42.07 6.0557 53.9993 30.1407
(PL x B6-Tcf7l2)F1 both 31.6417 7.3707 46.1615 17.1218
(RIII x B6-Tcf7l2)F1 both 61.5542 5.8271 73.0331 50.0752
(SEA x B6-Tcf7l2)F1 both 49.3696 5.6581 60.5158 38.2235
(SJL x B6-Tcf7l2)F1 both 45.0833 5.8271 56.5623 33.6044
(SM x B6-Tcf7l2)F1 both 41.66 5.7093 52.907 30.413
(SWR x B6-Tcf7l2)F1 both 25.8575 6.0557 37.7868 13.9282