Phenotype measure

ID, description, units MPD:59231   ASR   acoustic startle response (ASR) evoked by 120 dB sound pressure level   [amplitude]
Data set, strains Palmer3   F1 Tcf7l2   30 strains     sex: both     age: 7-14wks
Procedure acoustic startle test
Ontology mappings


  STRAIN COMPARISON PLOT
width:   ×  height:  pixels

Palmer3 - acoustic startle response (ASR) evoked by 120 dB sound pressure level



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains29 strains
Mean of the strain means39.3   amplitude 55.0   amplitude
Median of the strain means32.8   amplitude 49.2   amplitude
SD of the strain means± 24.0 ± 36.3
Coefficient of variation (CV)0.612 0.660
Min–max range of strain means10.0   –   95.2   amplitude 11.1   –   146   amplitude
Mean sample size per strain5.3   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 17905.4083 17905.4083 29.9795 < 0.0001
strain 28 213741.5048 7633.6252 12.7812 < 0.0001
sex:strain 28 27053.0733 966.1812 1.6177 0.0296
Residuals 245 146327.3719 597.2546


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(129S x B6-Tcf7l2)F1 f 95.2 40.9   5 18.3 0.43 55.1, 164.0 2.33
(129S x B6-Tcf7l2)F1 m 88.0 59.7   4 29.9 0.679 30.4, 171.0 0.91
(AJ x B6-Tcf7l2)F1 f 43.4 35.5   6 14.5 0.817 14.7, 100.0 0.17
(AJ x B6-Tcf7l2)F1 m 47.9 14.6   4 7.3 0.305 35.2, 67.0 -0.2
(AKR x B6-Tcf7l2)F1 f 15.0 4.48   4 2.24 0.299 9.9, 20.0 -1.01
(B6 x B6-Tcf7l2)F1 f 33.4 17.5   8 6.19 0.524 13.7, 69.0 -0.24
(B6 x B6-Tcf7l2)F1 m 58.1 32.9   9 11.0 0.566 15.4, 115.0 0.08
(BALB x B6-Tcf7l2)F1 f 29.4 15.5   5 6.93 0.527 13.1, 49.0 -0.41
(BALB x B6-Tcf7l2)F1 m 41.1 22.6   4 11.3 0.551 16.7, 69.6 -0.38
(BLKS x B6-Tcf7l2)F1 f 15.8 5.51   5 2.47 0.348 10.8, 23.6 -0.98
(BLKS x B6-Tcf7l2)F1 m 17.6 5.48   5 2.45 0.312 11.0, 24.9 -1.03
(BTBR x B6-Tcf7l2)F1 f 40.3 11.9   6 4.86 0.295 25.2, 61.1 0.04
(BTBR x B6-Tcf7l2)F1 m 67.7 30.7   5 13.7 0.453 30.8, 103.0 0.35
(BUB x B6-Tcf7l2)F1 f 26.3 15.7   5 7.03 0.598 9.5, 50.0 -0.54
(BUB x B6-Tcf7l2)F1 m 21.7 8.19   5 3.66 0.378 13.1, 34.0 -0.92
(C3H x B6-Tcf7l2)F1 f 73.1 27.6   7 10.4 0.378 48.3, 126.0 1.41
(C3H x B6-Tcf7l2)F1 m 71.0 19.3   4 9.63 0.271 49.3, 87.4 0.44
(C57L x B6-Tcf7l2)F1 f 13.1 9.84   4 4.92 0.754 5.1, 25.8 -1.09
(C57L x B6-Tcf7l2)F1 m 38.3 20.0   5 8.95 0.523 21.8, 71.5 -0.46
(C58 x B6-Tcf7l2)F1 f 15.2 12.4   4 6.18 0.811 8.0, 33.7 -1.0
(C58 x B6-Tcf7l2)F1 m 14.9 1.91   3 1.1 0.128 13.5, 17.1 -1.1
(CBA x B6-Tcf7l2)F1 f 60.7 25.1   4 12.6 0.414 34.3, 84.9 0.89
(CBA x B6-Tcf7l2)F1 m 94.2 26.3   6 10.7 0.279 69.8, 134.0 1.08
(DBA x B6-Tcf7l2)F1 f 10.0 2.27   5 1.02 0.227 7.2, 12.5 -1.22
(DBA x B6-Tcf7l2)F1 m 11.3 4.26   5 1.9 0.375 5.7, 16.8 -1.2
(DDY x B6-Tcf7l2)F1 f 59.6 27.7   5 12.4 0.464 17.0, 93.9 0.85
(DDY x B6-Tcf7l2)F1 m 69.4 19.7   5 8.81 0.284 44.7, 95.2 0.4
(FVB x B6-Tcf7l2)F1 f 51.1 11.0   4 5.49 0.215 42.4, 66.0 0.49
(FVB x B6-Tcf7l2)F1 m 71.0 33.4   7 12.6 0.47 27.5, 120.0 0.44
(ILN x B6-Tcf7l2)F1 f 21.9 19.2   4 9.6 0.876 7.6, 48.8 -0.72
(ILN x B6-Tcf7l2)F1 m 69.1 47.1   8 16.6 0.682 10.9, 154.0 0.39
(KK x B6-Tcf7l2)F1 f 67.5 27.5   6 11.2 0.407 39.0, 108.0 1.17
(KK x B6-Tcf7l2)F1 m 141.0 70.5   2   49.8 0.501 90.8, 190.0 2.37
(LP x B6-Tcf7l2)F1 f 12.4 5.41   6 2.21 0.435 6.3, 18.8 -1.12
(LP x B6-Tcf7l2)F1 m 16.8 3.25   2   2.3 0.194 14.5, 19.1 -1.05
(MA x B6-Tcf7l2)F1 f 13.9 9.8   5 4.38 0.706 6.4, 29.3 -1.06
(MA x B6-Tcf7l2)F1 m 11.1 3.36   5 1.5 0.303 6.0, 15.0 -1.21
(MRL x B6-Tcf7l2)F1 f 53.2 24.5   5 10.9 0.46 29.5, 91.4 0.58
(MRL x B6-Tcf7l2)F1 m 49.2 15.2   4 7.58 0.308 34.8, 62.5 -0.16
(NOD x B6-Tcf7l2)F1 f 14.4 3.89   6 1.59 0.27 9.0, 20.2 -1.04
(NOD x B6-Tcf7l2)F1 m 16.8 11.0   7 4.17 0.658 7.8, 39.0 -1.05
(NON x B6-Tcf7l2)F1 f 32.3 17.4   7 6.58 0.539 9.8, 60.1 -0.29
(NON x B6-Tcf7l2)F1 m 43.1 31.9   8 11.3 0.741 11.2, 106.0 -0.33
(NZB x B6-Tcf7l2)F1 f 57.0 21.7   8 7.67 0.381 20.8, 92.5 0.74
(NZB x B6-Tcf7l2)F1 m 82.3 34.8   9 11.6 0.423 35.0, 129.0 0.75
(NZW x B6-Tcf7l2)F1 f 64.8 29.6   4 14.8 0.456 23.5, 93.1 1.06
(NZW x B6-Tcf7l2)F1 m 89.2 29.6   5 13.3 0.332 57.8, 132.0 0.94
(PL x B6-Tcf7l2)F1 f 15.5 5.74   6 2.34 0.37 10.3, 24.1 -0.99
(PL x B6-Tcf7l2)F1 m 12.0 8.2   2   5.8 0.684 6.2, 17.8 -1.18
(RIII x B6-Tcf7l2)F1 f 78.8 21.0   5 9.39 0.266 51.4, 101.0 1.65
(RIII x B6-Tcf7l2)F1 m 88.5 15.7   4 7.85 0.177 65.7, 100.0 0.92
(SEA x B6-Tcf7l2)F1 f 29.4 21.7   5 9.71 0.737 14.5, 66.4 -0.41
(SEA x B6-Tcf7l2)F1 m 28.2 25.1   7 9.5 0.89 13.9, 84.1 -0.74
(SJL x B6-Tcf7l2)F1 f 25.1 15.5   6 6.33 0.619 9.7, 48.2 -0.59
(SJL x B6-Tcf7l2)F1 m 35.0 14.2   4 7.12 0.407 16.1, 49.8 -0.55
(SM x B6-Tcf7l2)F1 f 73.2 26.4   5 11.8 0.361 37.0, 102.0 1.41
(SM x B6-Tcf7l2)F1 m 146.0 32.7   5 14.6 0.224 122.0, 202.0 2.5
(SWR x B6-Tcf7l2)F1 f 37.2 16.9   5 7.56 0.454 22.1, 64.6 -0.09
(SWR x B6-Tcf7l2)F1 m 55.8 20.0   4 9.98 0.358 36.2, 79.5 0.02


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Tcf7l2)F1 f 95.18 10.9294 116.7075 73.6525
(129S x B6-Tcf7l2)F1 m 87.95 12.2194 112.0185 63.8815
(AJ x B6-Tcf7l2)F1 f 43.4333 9.9771 63.0852 23.7815
(AJ x B6-Tcf7l2)F1 m 47.85 12.2194 71.9185 23.7815
(B6 x B6-Tcf7l2)F1 f 33.3875 8.6404 50.4065 16.3685
(B6 x B6-Tcf7l2)F1 m 58.1 8.1463 74.1456 42.0544
(BALB x B6-Tcf7l2)F1 f 29.44 10.9294 50.9675 7.9125
(BALB x B6-Tcf7l2)F1 m 41.075 12.2194 65.1435 17.0065
(BLKS x B6-Tcf7l2)F1 f 15.84 10.9294 37.3675 0.0
(BLKS x B6-Tcf7l2)F1 m 17.6 10.9294 39.1275 0.0
(BTBR x B6-Tcf7l2)F1 f 40.2667 9.9771 59.9185 20.6148
(BTBR x B6-Tcf7l2)F1 m 67.66 10.9294 89.1875 46.1325
(BUB x B6-Tcf7l2)F1 f 26.28 10.9294 47.8075 4.7525
(BUB x B6-Tcf7l2)F1 m 21.66 10.9294 43.1875 0.1325
(C3H x B6-Tcf7l2)F1 f 73.0857 9.237 91.2798 54.8917
(C3H x B6-Tcf7l2)F1 m 71.025 12.2194 95.0935 46.9565
(C57L x B6-Tcf7l2)F1 f 13.05 12.2194 37.1185 0.0
(C57L x B6-Tcf7l2)F1 m 38.28 10.9294 59.8075 16.7525
(C58 x B6-Tcf7l2)F1 f 15.25 12.2194 39.3185 0.0
(C58 x B6-Tcf7l2)F1 m 14.9333 14.1097 42.7252 0.0
(CBA x B6-Tcf7l2)F1 f 60.7 12.2194 84.7685 36.6315
(CBA x B6-Tcf7l2)F1 m 94.2167 9.9771 113.8685 74.5648
(DBA x B6-Tcf7l2)F1 f 10.02 10.9294 31.5475 0.0
(DBA x B6-Tcf7l2)F1 m 11.34 10.9294 32.8675 0.0
(DDY x B6-Tcf7l2)F1 f 59.64 10.9294 81.1675 38.1125
(DDY x B6-Tcf7l2)F1 m 69.4 10.9294 90.9275 47.8725
(FVB x B6-Tcf7l2)F1 f 51.1 12.2194 75.1685 27.0315
(FVB x B6-Tcf7l2)F1 m 70.9571 9.237 89.1512 52.7631
(ILN x B6-Tcf7l2)F1 f 21.925 12.2194 45.9935 0.0
(ILN x B6-Tcf7l2)F1 m 69.0625 8.6404 86.0815 52.0435
(KK x B6-Tcf7l2)F1 f 67.55 9.9771 87.2018 47.8982
(KK x B6-Tcf7l2)F1 m 140.65 17.2808 174.688 106.612
(LP x B6-Tcf7l2)F1 f 12.45 9.9771 32.1018 0.0
(LP x B6-Tcf7l2)F1 m 16.8 17.2808 50.838 0.0
(MA x B6-Tcf7l2)F1 f 13.88 10.9294 35.4075 0.0
(MA x B6-Tcf7l2)F1 m 11.1 10.9294 32.6275 0.0
(MRL x B6-Tcf7l2)F1 f 53.2 10.9294 74.7275 31.6725
(MRL x B6-Tcf7l2)F1 m 49.2 12.2194 73.2685 25.1315
(NOD x B6-Tcf7l2)F1 f 14.4333 9.9771 34.0852 0.0
(NOD x B6-Tcf7l2)F1 m 16.7857 9.237 34.9798 0.0
(NON x B6-Tcf7l2)F1 f 32.3 9.237 50.4941 14.1059
(NON x B6-Tcf7l2)F1 m 43.0625 8.6404 60.0815 26.0435
(NZB x B6-Tcf7l2)F1 f 56.975 8.6404 73.994 39.956
(NZB x B6-Tcf7l2)F1 m 82.3222 8.1463 98.3679 66.2766
(NZW x B6-Tcf7l2)F1 f 64.85 12.2194 88.9185 40.7815
(NZW x B6-Tcf7l2)F1 m 89.22 10.9294 110.7475 67.6925
(PL x B6-Tcf7l2)F1 f 15.5333 9.9771 35.1852 0.0
(PL x B6-Tcf7l2)F1 m 12.0 17.2808 46.038 0.0
(RIII x B6-Tcf7l2)F1 f 78.84 10.9294 100.3675 57.3125
(RIII x B6-Tcf7l2)F1 m 88.475 12.2194 112.5435 64.4065
(SEA x B6-Tcf7l2)F1 f 29.44 10.9294 50.9675 7.9125
(SEA x B6-Tcf7l2)F1 m 28.2429 9.237 46.4369 10.0488
(SJL x B6-Tcf7l2)F1 f 25.0667 9.9771 44.7185 5.4148
(SJL x B6-Tcf7l2)F1 m 34.975 12.2194 59.0435 10.9065
(SM x B6-Tcf7l2)F1 f 73.18 10.9294 94.7075 51.6525
(SM x B6-Tcf7l2)F1 m 146.14 10.9294 167.6675 124.6125
(SWR x B6-Tcf7l2)F1 f 37.18 10.9294 58.7075 15.6525
(SWR x B6-Tcf7l2)F1 m 55.825 12.2194 79.8935 31.7565


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Tcf7l2)F1 both 91.565 8.197 107.7106 75.4194
(AJ x B6-Tcf7l2)F1 both 45.6417 7.8876 61.1778 30.1055
(B6 x B6-Tcf7l2)F1 both 45.7437 5.9376 57.4389 34.0486
(BALB x B6-Tcf7l2)F1 both 35.2575 8.197 51.4031 19.1119
(BLKS x B6-Tcf7l2)F1 both 16.72 7.7282 31.9422 1.4978
(BTBR x B6-Tcf7l2)F1 both 53.9633 7.3992 68.5375 39.3892
(BUB x B6-Tcf7l2)F1 both 23.97 7.7282 39.1922 8.7478
(C3H x B6-Tcf7l2)F1 both 72.0554 7.6589 87.1411 56.9696
(C57L x B6-Tcf7l2)F1 both 25.665 8.197 41.8106 9.5194
(C58 x B6-Tcf7l2)F1 both 15.0917 9.3327 33.4743 0.0
(CBA x B6-Tcf7l2)F1 both 77.4583 7.8876 92.9945 61.9222
(DBA x B6-Tcf7l2)F1 both 10.68 7.7282 25.9022 0.0
(DDY x B6-Tcf7l2)F1 both 64.52 7.7282 79.7422 49.2978
(FVB x B6-Tcf7l2)F1 both 61.0286 7.6589 76.1143 45.9429
(ILN x B6-Tcf7l2)F1 both 45.4937 7.4828 60.2326 30.7549
(KK x B6-Tcf7l2)F1 both 104.1 9.9771 123.7518 84.4482
(LP x B6-Tcf7l2)F1 both 14.625 9.9771 34.2768 0.0
(MA x B6-Tcf7l2)F1 both 12.49 7.7282 27.7122 0.0
(MRL x B6-Tcf7l2)F1 both 51.2 8.197 67.3456 35.0544
(NOD x B6-Tcf7l2)F1 both 15.6095 6.7982 29.0 2.2191
(NON x B6-Tcf7l2)F1 both 37.6813 6.3241 50.1379 25.2246
(NZB x B6-Tcf7l2)F1 both 69.6486 5.9376 81.3438 57.9534
(NZW x B6-Tcf7l2)F1 both 77.035 8.197 93.1806 60.8894
(PL x B6-Tcf7l2)F1 both 13.7667 9.9771 33.4185 0.0
(RIII x B6-Tcf7l2)F1 both 83.6575 8.197 99.8031 67.5119
(SEA x B6-Tcf7l2)F1 both 28.8414 7.1549 42.9345 14.7484
(SJL x B6-Tcf7l2)F1 both 30.0208 7.8876 45.557 14.4847
(SM x B6-Tcf7l2)F1 both 109.66 7.7282 124.8822 94.4378
(SWR x B6-Tcf7l2)F1 both 46.5025 8.197 62.6481 30.3569