Phenotype measure

ID, description, units MPD:59223   d3_tone   percentage of time freezing to tone on day 3   [%]
Data set, strains Palmer3   F1 Tcf7l2   30 strains     sex: both     age: 7-14wks
Procedure fear conditioning test
Ontology mappings


  STRAIN COMPARISON PLOT
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Palmer3 - percentage of time freezing to tone on day 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means46.8   % 37.6   %
Median of the strain means48.8   % 37.0   %
SD of the strain means± 19.8 ± 20.6
Coefficient of variation (CV)0.422 0.548
Min–max range of strain means7.13   –   85.3   % 3.30   –   75.9   %
Mean sample size per strain5.3   mice 4.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 8372.2435 8372.2435 13.3431 0.0003
strain 25 76192.4992 3047.7 4.8572 < 0.0001
sex:strain 25 17600.8981 704.0359 1.122 0.3189
Residuals 227 142433.6053 627.4608


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(129S x B6-Tcf7l2)F1 f 62.3 24.1   6 9.82 0.386 32.0, 88.9 0.79
(129S x B6-Tcf7l2)F1 m 61.6 19.8   4 9.9 0.321 44.4, 79.0 1.17
(AJ x B6-Tcf7l2)F1 f 51.1 24.1   6 9.82 0.471 30.4, 93.8 0.22
(AJ x B6-Tcf7l2)F1 m 70.2 22.0   4 11.0 0.314 48.7, 94.6 1.58
(AKR x B6-Tcf7l2)F1 f 66.8 11.4   4 5.72 0.171 53.6, 78.6 1.01
(AKR x B6-Tcf7l2)F1 m 16.5 0.0   1   0.0 0.0 16.5, 16.5 -1.02
(B6 x B6-Tcf7l2)F1 f 38.2 23.4   9 7.81 0.614 11.4, 78.1 -0.43
(B6 x B6-Tcf7l2)F1 m 28.1 20.0   9 6.65 0.711 6.6, 63.8 -0.46
(BALB x B6-Tcf7l2)F1 f 38.8 35.6   5 15.9 0.917 1.8, 82.1 -0.4
(BALB x B6-Tcf7l2)F1 m 9.85 15.6   4 7.82 1.59 0.0, 33.1 -1.35
(BLKS x B6-Tcf7l2)F1 f 48.3 20.7   5 9.25 0.428 21.4, 73.2 0.08
(BLKS x B6-Tcf7l2)F1 m 38.7 23.9   4 11.9 0.616 10.9, 69.2 0.05
(BTBR x B6-Tcf7l2)F1 f 59.3 19.6   6 8.02 0.331 33.9, 94.2 0.63
(BTBR x B6-Tcf7l2)F1 m 51.1 25.3   5 11.3 0.495 21.9, 77.8 0.66
(BUB x B6-Tcf7l2)F1 f 60.9 17.6   5 7.87 0.289 43.3, 88.0 0.71
(BUB x B6-Tcf7l2)F1 m 48.5 39.4   5 17.6 0.812 6.3, 91.1 0.53
(C3H x B6-Tcf7l2)F1 f 44.7 34.8   7 13.2 0.778 0.0, 91.3 -0.11
(C3H x B6-Tcf7l2)F1 m 33.3 25.2   5 11.3 0.755 13.0, 75.0 -0.21
(C57L x B6-Tcf7l2)F1 f 61.6 31.8   4 15.9 0.516 24.7, 91.9 0.75
(C57L x B6-Tcf7l2)F1 m 22.6 20.0   5 8.94 0.884 5.4, 56.9 -0.73
(C58 x B6-Tcf7l2)F1 f 7.13 5.09   3 2.94 0.714 1.3, 10.7 -2.01
(C58 x B6-Tcf7l2)F1 m 3.3 0.0   1   0.0 0.0 3.3, 3.3 -1.66
(CBA x B6-Tcf7l2)F1 f 14.4 12.5   4 6.24 0.865 3.8, 32.4 -1.64
(CBA x B6-Tcf7l2)F1 m 11.4 8.87   6 3.62 0.777 1.2, 25.5 -1.27
(DBA x B6-Tcf7l2)F1 f 19.5 6.71   3 3.87 0.345 15.2, 27.2 -1.38
(DBA x B6-Tcf7l2)F1 m 17.4 6.78   5 3.03 0.389 9.0, 23.2 -0.98
(DDY x B6-Tcf7l2)F1 f 57.0 29.1   5 13.0 0.51 23.4, 95.6 0.52
(DDY x B6-Tcf7l2)F1 m 38.0 34.1   5 15.3 0.898 1.4, 78.3 0.02
(FVB x B6-Tcf7l2)F1 f 33.1 18.4   4 9.18 0.554 7.2, 50.5 -0.69
(FVB x B6-Tcf7l2)F1 m 39.9 38.0   5 17.0 0.951 1.8, 89.3 0.11
(ILN x B6-Tcf7l2)F1 f 31.4 28.4   4 14.2 0.903 9.0, 71.7 -0.78
(ILN x B6-Tcf7l2)F1 m 31.5 27.9   8 9.86 0.886 1.8, 80.8 -0.29
(KK x B6-Tcf7l2)F1 f 62.0 14.1   6 5.77 0.228 47.8, 83.0 0.77
(KK x B6-Tcf7l2)F1 m 75.9 0.0   1   0.0 0.0 75.9, 75.9 1.86
(LP x B6-Tcf7l2)F1 f 55.0 14.8   6 6.05 0.27 37.5, 78.8 0.42
(LP x B6-Tcf7l2)F1 m 57.1 0.0   1   0.0 0.0 57.1, 57.1 0.95
(MA x B6-Tcf7l2)F1 f 85.3 11.1   5 4.98 0.131 70.8, 98.6 1.95
(MA x B6-Tcf7l2)F1 m 67.7 22.5   5 10.1 0.332 37.5, 92.0 1.46
(MRL x B6-Tcf7l2)F1 f 41.7 24.7   5 11.1 0.593 14.3, 77.2 -0.26
(MRL x B6-Tcf7l2)F1 m 20.8 21.4   5 9.55 1.03 4.9, 57.3 -0.81
(NOD x B6-Tcf7l2)F1 f 71.3 23.5   6 9.57 0.329 26.0, 90.6 1.24
(NOD x B6-Tcf7l2)F1 m 54.6 29.9   7 11.3 0.548 6.7, 96.0 0.83
(NON x B6-Tcf7l2)F1 f 49.4 28.7   7 10.8 0.581 8.5, 84.4 0.13
(NON x B6-Tcf7l2)F1 m 21.0 29.8   8 10.5 1.42 0.5, 78.6 -0.81
(NZB x B6-Tcf7l2)F1 f 75.3 24.4   8 8.61 0.323 31.3, 94.6 1.44
(NZB x B6-Tcf7l2)F1 m 69.1 25.5   8 9.03 0.369 34.4, 97.8 1.53
(NZW x B6-Tcf7l2)F1 f 42.9 31.2   4 15.6 0.727 4.9, 80.9 -0.2
(NZW x B6-Tcf7l2)F1 m 40.0 9.91   5 4.43 0.248 31.3, 52.7 0.12
(PL x B6-Tcf7l2)F1 f 35.4 22.6   6 9.22 0.638 4.0, 59.0 -0.58
(PL x B6-Tcf7l2)F1 m 15.7 21.2   3 12.2 1.35 1.3, 40.0 -1.06
(RIII x B6-Tcf7l2)F1 f 21.0 25.9   6 10.6 1.23 3.1, 72.8 -1.31
(RIII x B6-Tcf7l2)F1 m 42.5 24.0   4 12.0 0.565 21.0, 76.7 0.24
(SEA x B6-Tcf7l2)F1 f 19.5 27.0   5 12.1 1.38 1.3, 63.4 -1.38
(SEA x B6-Tcf7l2)F1 m 9.13 17.3   7 6.53 1.89 0.0, 47.8 -1.38
(SJL x B6-Tcf7l2)F1 f 21.5 11.4   6 4.65 0.531 11.2, 40.6 -1.28
(SJL x B6-Tcf7l2)F1 m 61.3 13.4   3 7.72 0.218 46.5, 72.5 1.15
(SM x B6-Tcf7l2)F1 f 66.3 27.4   5 12.3 0.414 26.3, 91.5 0.99
(SM x B6-Tcf7l2)F1 m 34.4 32.5   5 14.5 0.945 3.6, 88.8 -0.15
(SWR x B6-Tcf7l2)F1 f 62.4 35.2   5 15.8 0.564 9.4, 93.3 0.79
(SWR x B6-Tcf7l2)F1 m 36.0 28.9   4 14.5 0.802 0.9, 68.3 -0.08


  LEAST SQUARES MEANS (ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Tcf7l2)F1 f 62.3333 10.2263 82.4839 42.1828
(129S x B6-Tcf7l2)F1 m 61.65 12.5246 86.3293 36.9707
(AJ x B6-Tcf7l2)F1 f 51.1333 10.2263 71.2839 30.9828
(AJ x B6-Tcf7l2)F1 m 70.15 12.5246 94.8293 45.4707
(B6 x B6-Tcf7l2)F1 f 38.2 8.3497 54.6529 21.7471
(B6 x B6-Tcf7l2)F1 m 28.0667 8.3497 44.5195 11.6138
(BALB x B6-Tcf7l2)F1 f 38.78 11.2023 60.8538 16.7062
(BALB x B6-Tcf7l2)F1 m 9.85 12.5246 34.5293 0.0
(BLKS x B6-Tcf7l2)F1 f 48.3 11.2023 70.3738 26.2262
(BLKS x B6-Tcf7l2)F1 m 38.7 12.5246 63.3793 14.0207
(BTBR x B6-Tcf7l2)F1 f 59.3 10.2263 79.4506 39.1494
(BTBR x B6-Tcf7l2)F1 m 51.08 11.2023 73.1538 29.0062
(BUB x B6-Tcf7l2)F1 f 60.9 11.2023 82.9738 38.8262
(BUB x B6-Tcf7l2)F1 m 48.5 11.2023 70.5738 26.4262
(C3H x B6-Tcf7l2)F1 f 44.7143 9.4677 63.3701 26.0585
(C3H x B6-Tcf7l2)F1 m 33.32 11.2023 55.3938 11.2462
(C57L x B6-Tcf7l2)F1 f 61.55 12.5246 86.2293 36.8707
(C57L x B6-Tcf7l2)F1 m 22.62 11.2023 44.6938 0.5462
(CBA x B6-Tcf7l2)F1 f 14.425 12.5246 39.1043 0.0
(CBA x B6-Tcf7l2)F1 m 11.4167 10.2263 31.5672 0.0
(DBA x B6-Tcf7l2)F1 f 19.4667 14.4621 47.9639 0.0
(DBA x B6-Tcf7l2)F1 m 17.42 11.2023 39.4938 0.0
(DDY x B6-Tcf7l2)F1 f 57.02 11.2023 79.0938 34.9462
(DDY x B6-Tcf7l2)F1 m 38.0 11.2023 60.0738 15.9262
(FVB x B6-Tcf7l2)F1 f 33.15 12.5246 57.8293 8.4707
(FVB x B6-Tcf7l2)F1 m 39.92 11.2023 61.9938 17.8462
(ILN x B6-Tcf7l2)F1 f 31.45 12.5246 56.1293 6.7707
(ILN x B6-Tcf7l2)F1 m 31.4875 8.8562 48.9384 14.0366
(MA x B6-Tcf7l2)F1 f 85.34 11.2023 107.4138 63.2662
(MA x B6-Tcf7l2)F1 m 67.7 11.2023 89.7738 45.6262
(MRL x B6-Tcf7l2)F1 f 41.7 11.2023 63.7738 19.6262
(MRL x B6-Tcf7l2)F1 m 20.8 11.2023 42.8738 0.0
(NOD x B6-Tcf7l2)F1 f 71.2833 10.2263 91.4339 51.1328
(NOD x B6-Tcf7l2)F1 m 54.6 9.4677 73.2558 35.9442
(NON x B6-Tcf7l2)F1 f 49.3857 9.4677 68.0415 30.7299
(NON x B6-Tcf7l2)F1 m 21.0 8.8562 38.4509 3.5491
(NZB x B6-Tcf7l2)F1 f 75.325 8.8562 92.7759 57.8741
(NZB x B6-Tcf7l2)F1 m 69.1 8.8562 86.5509 51.6491
(NZW x B6-Tcf7l2)F1 f 42.875 12.5246 67.5543 18.1957
(NZW x B6-Tcf7l2)F1 m 39.98 11.2023 62.0538 17.9062
(PL x B6-Tcf7l2)F1 f 35.4 10.2263 55.5506 15.2494
(PL x B6-Tcf7l2)F1 m 15.7 14.4621 44.1972 0.0
(RIII x B6-Tcf7l2)F1 f 20.9833 10.2263 41.1339 0.8328
(RIII x B6-Tcf7l2)F1 m 42.5 12.5246 67.1793 17.8207
(SEA x B6-Tcf7l2)F1 f 19.54 11.2023 41.6138 0.0
(SEA x B6-Tcf7l2)F1 m 9.1286 9.4677 27.7844 0.0
(SJL x B6-Tcf7l2)F1 f 21.4667 10.2263 41.6172 1.3161
(SJL x B6-Tcf7l2)F1 m 61.3 14.4621 89.7972 32.8028
(SM x B6-Tcf7l2)F1 f 66.28 11.2023 88.3538 44.2062
(SM x B6-Tcf7l2)F1 m 34.38 11.2023 56.4538 12.3062
(SWR x B6-Tcf7l2)F1 f 62.44 11.2023 84.5138 40.3662
(SWR x B6-Tcf7l2)F1 m 36.025 12.5246 60.7043 11.3457


  LEAST SQUARES MEANS (ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(129S x B6-Tcf7l2)F1 both 61.9917 8.0846 77.9221 46.0612
(AJ x B6-Tcf7l2)F1 both 60.6417 8.0846 76.5721 44.7112
(B6 x B6-Tcf7l2)F1 both 33.1333 5.9041 44.7673 21.4994
(BALB x B6-Tcf7l2)F1 both 24.315 8.4017 40.8704 7.7596
(BLKS x B6-Tcf7l2)F1 both 43.5 8.4017 60.0554 26.9446
(BTBR x B6-Tcf7l2)F1 both 55.19 7.584 70.1341 40.2459
(BUB x B6-Tcf7l2)F1 both 54.7 7.9212 70.3086 39.0914
(C3H x B6-Tcf7l2)F1 both 39.0171 7.3336 53.4679 24.5664
(C57L x B6-Tcf7l2)F1 both 42.085 8.4017 58.6404 25.5296
(CBA x B6-Tcf7l2)F1 both 12.9208 8.0846 28.8513 0.0
(DBA x B6-Tcf7l2)F1 both 18.4433 9.1467 36.4666 0.4201
(DDY x B6-Tcf7l2)F1 both 47.51 7.9212 63.1186 31.9014
(FVB x B6-Tcf7l2)F1 both 36.535 8.4017 53.0904 19.9796
(ILN x B6-Tcf7l2)F1 both 31.4687 7.6697 46.5817 16.3558
(MA x B6-Tcf7l2)F1 both 76.52 7.9212 92.1286 60.9114
(MRL x B6-Tcf7l2)F1 both 31.25 7.9212 46.8586 15.6414
(NOD x B6-Tcf7l2)F1 both 62.9417 6.968 76.672 49.2114
(NON x B6-Tcf7l2)F1 both 35.1929 6.4821 47.9656 22.4201
(NZB x B6-Tcf7l2)F1 both 72.2125 6.2623 84.5522 59.8728
(NZW x B6-Tcf7l2)F1 both 41.4275 8.4017 57.9829 24.8721
(PL x B6-Tcf7l2)F1 both 25.55 8.8562 43.0009 8.0991
(RIII x B6-Tcf7l2)F1 both 31.7417 8.0846 47.6721 15.8112
(SEA x B6-Tcf7l2)F1 both 14.3343 7.3336 28.785 0.0
(SJL x B6-Tcf7l2)F1 both 41.3833 8.8562 58.8342 23.9324
(SM x B6-Tcf7l2)F1 both 50.33 7.9212 65.9386 34.7214
(SWR x B6-Tcf7l2)F1 both 49.2325 8.4017 65.7879 32.6771