Project measure / variable:   Schughart3   day_survivalB

ID, description, units MPD:57182   day_survivalB   survival, post-infection   [d]  2000 FFU group  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure health assessment
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  STRAIN COMPARISON PLOT
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Schughart3 - survival, post-infection 2000 FFU group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means7.83   d 8.07   d
Median of the strain means6.55   d 6.89   d
SD of the strain means± 3.94 ± 3.64
Coefficient of variation (CV)0.503 0.451
Min–max range of strain means4.50   –   14.0   d 4.82   –   14.0   d
Mean sample size per strain10.1   mice 10.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.0839 1.0839 1.045 0.3083
strain 7 2066.4012 295.2002 284.6176 < 0.0001
sex:strain 7 10.1967 1.4567 1.4045 0.2075
Residuals 150 155.5772 1.0372


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.2 1.48   10 0.467 0.205 6.0, 11.0 -0.16
129S1/SvImJ m 8.0 1.41   10 0.447 0.177 7.0, 11.0 -0.02
A/J f 4.67 0.778   12 0.225 0.167 4.0, 6.0 -0.8
A/J m 5.0 1.0   11 0.302 0.2 4.0, 6.0 -0.84
C57BL/6J f 5.91 0.701   11 0.211 0.119 5.0, 7.0 -0.49
C57BL/6J m 6.9 0.568   10 0.18 0.0823 6.0, 8.0 -0.32
CAST/EiJ f 5.2 0.789   10 0.249 0.152 4.0, 6.0 -0.67
CAST/EiJ m 5.54 0.66   13 0.183 0.119 4.0, 6.0 -0.69
NOD/ShiLtJ f 7.2 1.14   10 0.359 0.158 5.0, 9.0 -0.16
NOD/ShiLtJ m 6.89 1.27   9 0.423 0.184 5.0, 9.0 -0.32
NZO/HlLtJ f 14.0 0.0   9 0.0 0.0 14.0, 14.0 1.57
NZO/HlLtJ m 13.4 2.11   11 0.636 0.158 7.0, 14.0 1.46
PWK/PhJ f 14.0 0.0   11 0.0 0.0 14.0, 14.0 1.57
PWK/PhJ m 14.0 0.0   10 0.0 0.0 14.0, 14.0 1.63
WSB/EiJ f 4.5 0.535   8 0.189 0.119 4.0, 5.0 -0.85
WSB/EiJ m 4.82 1.08   11 0.325 0.224 3.0, 7.0 -0.89


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.2 0.3221 7.8363 6.5637
129S1/SvImJ m 8.0 0.3221 8.6363 7.3637
A/J f 4.6667 0.294 5.2476 4.0858
A/J m 5.0 0.3071 5.6067 4.3933
C57BL/6J f 5.9091 0.3071 6.5158 5.3024
C57BL/6J m 6.9 0.3221 7.5363 6.2637
CAST/EiJ f 5.2 0.3221 5.8363 4.5637
CAST/EiJ m 5.5385 0.2825 6.0966 4.9803
NOD/ShiLtJ f 7.2 0.3221 7.8363 6.5637
NOD/ShiLtJ m 6.8889 0.3395 7.5597 6.2181
NZO/HlLtJ f 14.0 0.3395 14.6708 13.3292
NZO/HlLtJ m 13.3636 0.3071 13.9704 12.7569
PWK/PhJ f 14.0 0.3071 14.6067 13.3933
PWK/PhJ m 14.0 0.3221 14.6363 13.3637
WSB/EiJ f 4.5 0.3601 5.2115 3.7885
WSB/EiJ m 4.8182 0.3071 5.4249 4.2114


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.6 0.2277 8.05 7.15
A/J both 4.8333 0.2126 5.2533 4.4133
C57BL/6J both 6.4045 0.2225 6.8442 5.9649
CAST/EiJ both 5.3692 0.2142 5.7924 4.946
NOD/ShiLtJ both 7.0444 0.234 7.5067 6.5821
NZO/HlLtJ both 13.6818 0.2289 14.134 13.2296
PWK/PhJ both 14.0 0.2225 14.4396 13.5604
WSB/EiJ both 4.6591 0.2366 5.1266 4.1916




  GWAS USING LINEAR MIXED MODELS