Project measure / variable:   Schughart3   pctbwB_d5

ID, description, units MPD:57135   pctbwB_d5   body weight as percent of baseline, 2000 FFU group   [%]  post-infection day 5  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 2000 FFU group post-infection day 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains8 strains
Mean of the strain means80.1   % 79.5   %
Median of the strain means76.1   % 75.7   %
SD of the strain means± 9.78 ± 8.62
Coefficient of variation (CV)0.122 0.108
Min–max range of strain means72.6   –   95.5   % 72.7   –   94.2   %
Mean sample size per strain7.6   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 15.9874 15.9874 0.9346 0.336
strain 6 9075.3261 1512.5543 88.4236 < 0.0001
sex:strain 6 40.9496 6.8249 0.399 0.8781
Residuals 101 1727.6833 17.1058


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 77.6 6.64   10 2.1 0.0855 71.5, 95.4 -0.25
129S1/SvImJ m 79.0 5.43   10 1.72 0.0687 72.5, 91.4 -0.06
A/J f 73.1 2.75   2   1.95 0.0376 71.2, 75.0 -0.71
A/J m 73.2 1.13   5 0.506 0.0155 72.2, 75.0 -0.73
C57BL/6J f 72.6 1.4   8 0.495 0.0193 71.4, 75.8 -0.77
C57BL/6J m 74.9 2.83   10 0.895 0.0378 71.4, 79.3 -0.54
CAST/EiJ f 73.0 1.26   4 0.631 0.0173 71.8, 74.2 -0.72
CAST/EiJ m 72.7 2.13   8 0.753 0.0293 70.6, 76.3 -0.79
NOD/ShiLtJ f 76.1 2.47   9 0.824 0.0325 72.3, 78.8 -0.41
NOD/ShiLtJ m 76.5 2.79   8 0.988 0.0365 73.1, 81.2 -0.35
NZO/HlLtJ f 95.5 2.6   9 0.866 0.0272 91.1, 99.3 1.58
NZO/HlLtJ m 94.2 6.73   11 2.03 0.0714 75.5, 99.7 1.7
PWK/PhJ f 92.7 4.29   11 1.29 0.0463 88.6, 101.0 1.29
PWK/PhJ m 91.9 3.89   10 1.23 0.0423 86.2, 99.2 1.44
WSB/EiJ m 73.7 3.85   2   2.72 0.0522 71.0, 76.4 -0.67


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 77.641 1.3079 80.2355 75.0465
129S1/SvImJ m 78.969 1.3079 81.5635 76.3745
A/J f 73.095 2.9245 78.8965 67.2935
A/J m 73.152 1.8496 76.8212 69.4828
C57BL/6J f 72.6437 1.4623 75.5445 69.743
C57BL/6J m 74.868 1.3079 77.4625 72.2735
CAST/EiJ f 73.01 2.068 77.1123 68.9077
CAST/EiJ m 72.6825 1.4623 75.5832 69.7818
NOD/ShiLtJ f 76.0878 1.3786 78.8226 73.3529
NOD/ShiLtJ m 76.54 1.4623 79.4407 73.6393
NZO/HlLtJ f 95.4633 1.3786 98.1982 92.7285
NZO/HlLtJ m 94.2291 1.247 96.7029 91.7553
PWK/PhJ f 92.7173 1.247 95.191 90.2435
PWK/PhJ m 91.915 1.3079 94.5095 89.3205


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 78.305 0.9248 80.1396 76.4704
A/J both 73.1235 1.7302 76.5557 69.6913
C57BL/6J both 73.7559 0.9809 75.7018 71.81
CAST/EiJ both 72.8463 1.2664 75.3584 70.3341
NOD/ShiLtJ both 76.3139 1.0048 78.3072 74.3205
NZO/HlLtJ both 94.8462 0.9295 96.69 93.0024
PWK/PhJ both 92.3161 0.9036 94.1085 90.5237




  GWAS USING LINEAR MIXED MODELS