Project measure / variable:   Schughart3   pctbwB_d3

ID, description, units MPD:57133   pctbwB_d3   body weight as percent of baseline, 2000 FFU group   [%]  post-infection day 3  
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 2000 FFU group post-infection day 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means82.8   % 84.5   %
Median of the strain means80.6   % 82.8   %
SD of the strain means± 5.34 ± 4.53
Coefficient of variation (CV)0.0645 0.0537
Min–max range of strain means78.4   –   94.4   % 80.2   –   94.2   %
Mean sample size per strain10.1   mice 10.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 131.6754 131.6754 12.5462 0.0005
strain 7 3392.3372 484.6196 46.175 < 0.0001
sex:strain 7 45.2657 6.4665 0.6161 0.742
Residuals 149 1563.7967 10.4953


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 86.5 6.04   10 1.91 0.0699 81.7, 102.0 0.7
129S1/SvImJ m 87.5 2.5   10 0.791 0.0286 84.8, 92.2 0.67
A/J f 81.3 1.87   12 0.541 0.0231 79.0, 84.6 -0.28
A/J m 81.7 1.61   11 0.485 0.0197 78.8, 84.0 -0.61
C57BL/6J f 79.9 1.53   11 0.462 0.0192 77.7, 81.9 -0.54
C57BL/6J m 82.7 2.13   10 0.672 0.0257 79.0, 86.4 -0.39
CAST/EiJ f 78.4 4.41   10 1.39 0.0562 70.6, 82.3 -0.82
CAST/EiJ m 80.2 1.76   13 0.489 0.022 76.8, 82.6 -0.94
NOD/ShiLtJ f 79.3 1.98   10 0.625 0.0249 77.3, 84.1 -0.65
NOD/ShiLtJ m 81.6 2.54   9 0.848 0.0311 77.5, 85.0 -0.63
NZO/HlLtJ f 94.4 4.51   9 1.5 0.0478 84.7, 100.0 2.18
NZO/HlLtJ m 94.2 3.86   11 1.16 0.041 85.4, 97.9 2.15
PWK/PhJ f 82.7 3.46   11 1.04 0.0418 77.8, 89.0 -0.02
PWK/PhJ m 84.8 5.04   10 1.59 0.0594 77.3, 93.4 0.08
WSB/EiJ f 79.8 2.59   8 0.915 0.0324 76.2, 83.1 -0.56
WSB/EiJ m 82.9 2.21   10 0.699 0.0267 80.4, 85.9 -0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 86.459 1.0245 88.4834 84.4346
129S1/SvImJ m 87.517 1.0245 89.5414 85.4926
A/J f 81.2608 0.9352 83.1088 79.4129
A/J m 81.6936 0.9768 83.6238 79.7635
C57BL/6J f 79.9273 0.9768 81.8574 77.9971
C57BL/6J m 82.727 1.0245 84.7514 80.7026
CAST/EiJ f 78.383 1.0245 80.4074 76.3586
CAST/EiJ m 80.1715 0.8985 81.947 78.3961
NOD/ShiLtJ f 79.344 1.0245 81.3684 77.3196
NOD/ShiLtJ m 81.6478 1.0799 83.7816 79.5139
NZO/HlLtJ f 94.3711 1.0799 96.505 92.2373
NZO/HlLtJ m 94.2382 0.9768 96.1683 92.308
PWK/PhJ f 82.6818 0.9768 84.612 80.7517
PWK/PhJ m 84.783 1.0245 86.8074 82.7586
WSB/EiJ f 79.805 1.1454 82.0683 77.5417
WSB/EiJ m 82.89 1.0245 84.9144 80.8656


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 86.988 0.7244 88.4194 85.5566
A/J both 81.4772 0.6762 82.8133 80.1412
C57BL/6J both 81.3271 0.7078 82.7257 79.9286
CAST/EiJ both 79.2773 0.6813 80.6236 77.9309
NOD/ShiLtJ both 80.4959 0.7443 81.9665 79.0252
NZO/HlLtJ both 94.3046 0.7281 95.7433 92.866
PWK/PhJ both 83.7324 0.7078 85.1309 82.3339
WSB/EiJ both 81.3475 0.7683 82.8658 79.8292




  GWAS USING LINEAR MIXED MODELS