Phenotype measure:   Schughart3   pctbwB_d2

ID, description, units MPD:57132   pctbwB_d2   body weight as percent of baseline, 2000 FFU group   [%]  post-infection day 2   measure
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 2000 FFU group post-infection day 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means88.5   % 90.0   %
Median of the strain means87.6   % 88.8   %
SD of the strain means± 3.96 ± 3.63
Coefficient of variation (CV)0.0448 0.0403
Min–max range of strain means83.3   –   95.3   % 86.6   –   97.0   %
Mean sample size per strain10.1   mice 10.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 105.2291 105.2291 10.8593 0.0012
strain 7 1995.7339 285.1048 29.4218 < 0.0001
sex:strain 7 71.7592 10.2513 1.0579 0.3936
Residuals 150 1453.5384 9.6903


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 93.2 5.33   10 1.69 0.0572 85.0, 105.0 1.18
129S1/SvImJ m 94.0 2.88   10 0.911 0.0307 90.2, 98.3 1.1
A/J f 87.8 2.0   12 0.578 0.0228 84.7, 90.6 -0.18
A/J m 88.6 2.7   11 0.813 0.0304 84.4, 93.0 -0.39
C57BL/6J f 87.4 1.58   11 0.477 0.0181 84.9, 89.6 -0.28
C57BL/6J m 87.7 2.12   10 0.672 0.0242 83.3, 90.4 -0.64
CAST/EiJ f 86.0 6.18   10 1.96 0.0719 75.8, 92.9 -0.63
CAST/EiJ m 87.3 2.23   13 0.617 0.0255 83.8, 90.8 -0.75
NOD/ShiLtJ f 89.1 3.17   10 1.0 0.0356 83.6, 93.2 0.15
NOD/ShiLtJ m 89.0 1.86   9 0.619 0.0209 86.4, 91.5 -0.28
NZO/HlLtJ f 95.3 3.31   9 1.1 0.0347 87.8, 98.9 1.71
NZO/HlLtJ m 97.0 1.42   11 0.429 0.0146 94.6, 99.2 1.92
PWK/PhJ f 83.3 3.54   11 1.07 0.0425 76.1, 89.2 -1.32
PWK/PhJ m 86.6 2.44   10 0.77 0.0281 82.8, 89.9 -0.94
WSB/EiJ f 86.0 3.06   8 1.08 0.0355 81.7, 90.3 -0.63
WSB/EiJ m 90.0 2.59   11 0.78 0.0287 86.0, 94.4 -0.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 93.204 0.9844 95.1491 91.2589
129S1/SvImJ m 94.017 0.9844 95.9621 92.0719
A/J f 87.8033 0.8986 89.5789 86.0277
A/J m 88.5618 0.9386 90.4164 86.7073
C57BL/6J f 87.3809 0.9386 89.2355 85.5264
C57BL/6J m 87.692 0.9844 89.6371 85.7469
CAST/EiJ f 86.04 0.9844 87.9851 84.0949
CAST/EiJ m 87.2862 0.8634 88.9921 85.5802
NOD/ShiLtJ f 89.148 0.9844 91.0931 87.2029
NOD/ShiLtJ m 89.0078 1.0376 91.0581 86.9575
NZO/HlLtJ f 95.3389 1.0376 97.3892 93.2886
NZO/HlLtJ m 97.03 0.9386 98.8845 95.1755
PWK/PhJ f 83.3482 0.9386 85.2027 81.4936
PWK/PhJ m 86.626 0.9844 88.5711 84.6809
WSB/EiJ f 85.9962 1.1006 88.1709 83.8216
WSB/EiJ m 90.0 0.9386 91.8545 88.1455


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 93.6105 0.6961 94.9859 92.2351
A/J both 88.1826 0.6497 89.4663 86.8988
C57BL/6J both 87.5365 0.6801 88.8802 86.1927
CAST/EiJ both 86.6631 0.6547 87.9567 85.3695
NOD/ShiLtJ both 89.0779 0.7151 90.4909 87.6648
NZO/HlLtJ both 96.1844 0.6996 97.5667 94.8021
PWK/PhJ both 84.9871 0.6801 86.3308 83.6433
WSB/EiJ both 87.9981 0.7232 89.4271 86.5691




GWAS analysis not available: At least 12 strains are required