Phenotype measure:   Schughart3   pctbwB_d1

ID, description, units MPD:57131   pctbwB_d1   body weight as percent of baseline, 2000 FFU group   [%]  post-infection day 1   measure
influenza A (H3N2) virus study
Data set, strains Schughart3   inbred w/CC8   8 strains     sex: both     age: 7-13wks
Procedure body weight
Ontology mappings

  STRAIN COMPARISON PLOT
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Schughart3 - body weight as percent of baseline, 2000 FFU group post-infection day 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means95.9   % 96.1   %
Median of the strain means96.6   % 95.8   %
SD of the strain means± 2.58 ± 1.76
Coefficient of variation (CV)0.0268 0.0183
Min–max range of strain means92.5   –   99.6   % 93.2   –   98.6   %
Mean sample size per strain10.1   mice 10.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.5165 0.5165 0.0404 0.8411
strain 7 584.494 83.4991 6.5238 < 0.0001
sex:strain 7 99.6383 14.234 1.1121 0.3584
Residuals 150 1919.862 12.7991


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 99.6 3.23   10 1.02 0.0324 92.7, 104.0 1.43
129S1/SvImJ m 98.6 2.39   10 0.754 0.0242 95.0, 102.0 1.4
A/J f 96.8 3.11   12 0.899 0.0321 92.7, 103.0 0.34
A/J m 95.5 1.94   11 0.584 0.0203 90.6, 98.2 -0.36
C57BL/6J f 98.2 1.84   11 0.556 0.0188 95.0, 100.0 0.88
C57BL/6J m 98.6 1.86   10 0.589 0.0189 96.0, 102.0 1.4
CAST/EiJ f 93.6 5.49   10 1.74 0.0586 83.8, 98.4 -0.9
CAST/EiJ m 96.0 7.31   13 2.03 0.0762 80.3, 109.0 -0.08
NOD/ShiLtJ f 96.4 1.72   10 0.543 0.0178 94.8, 99.9 0.18
NOD/ShiLtJ m 95.5 2.84   9 0.947 0.0298 88.8, 97.8 -0.36
NZO/HlLtJ f 97.2 2.17   9 0.725 0.0224 91.7, 98.9 0.5
NZO/HlLtJ m 95.8 2.37   11 0.713 0.0247 91.4, 99.0 -0.19
PWK/PhJ f 92.5 4.86   11 1.47 0.0525 79.8, 98.7 -1.33
PWK/PhJ m 93.2 3.67   10 1.16 0.0394 88.1, 98.7 -1.67
WSB/EiJ f 93.1 3.38   8 1.2 0.0363 88.1, 98.1 -1.1
WSB/EiJ m 95.9 1.73   11 0.522 0.0181 92.8, 98.2 -0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 99.603 1.1313 101.8384 97.3676
129S1/SvImJ m 98.598 1.1313 100.8334 96.3626
A/J f 96.8358 1.0328 98.8765 94.7952
A/J m 95.5336 1.0787 97.665 93.4023
C57BL/6J f 98.1764 1.0787 100.3077 96.045
C57BL/6J m 98.552 1.1313 100.7874 96.3166
CAST/EiJ f 93.576 1.1313 95.8114 91.3406
CAST/EiJ m 95.9777 0.9922 97.9383 94.0171
NOD/ShiLtJ f 96.396 1.1313 98.6314 94.1606
NOD/ShiLtJ m 95.4944 1.1925 97.8508 93.1381
NZO/HlLtJ f 97.2422 1.1925 99.5985 94.8859
NZO/HlLtJ m 95.7509 1.0787 97.8823 93.6195
PWK/PhJ f 92.5309 1.0787 94.6623 90.3995
PWK/PhJ m 93.152 1.1313 95.3874 90.9166
WSB/EiJ f 93.0675 1.2649 95.5668 90.5682
WSB/EiJ m 95.8564 1.0787 97.9877 93.725


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 99.1005 0.8 100.6812 97.5198
A/J both 96.1847 0.7467 97.6601 94.7094
C57BL/6J both 98.3642 0.7816 99.9085 96.8199
CAST/EiJ both 94.7768 0.7524 96.2635 93.2902
NOD/ShiLtJ both 95.9452 0.8219 97.5692 94.3212
NZO/HlLtJ both 96.4966 0.804 98.0852 94.9079
PWK/PhJ both 92.8415 0.7816 94.3858 91.2971
WSB/EiJ both 94.4619 0.8312 96.1043 92.8196




GWAS analysis not available: At least 12 strains are required