Project measure / variable:   GMC20   RF_17

ID, description, units MPD:56918   RF_17   rheumatoid factor (plasma RF)    at age 16-17wks  
Data set, strains GMC20   inbred w/CC8   7 strains     sex: both     age: 16-17wks
Procedure autoantibody quantification
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  STRAIN COMPARISON PLOT
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GMC20 - rheumatoid factor (plasma RF) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means0.218   None 0.190   None
Median of the strain means0.200   None 0.175   None
SD of the strain means± 0.0457 ± 0.0388
Coefficient of variation (CV)0.210 0.204
Min–max range of strain means0.171   –   0.278   None 0.158   –   0.269   None
Mean sample size per strain3.5   mice 3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0065 0.0065 8.6891 0.0061
strain 4 0.062 0.0155 20.638 < 0.0001
sex:strain 4 0.005 0.0012 1.662 0.1848
Residuals 30 0.0225 0.0008


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.171 0.00961   4 0.0048 0.0564 0.158, 0.179 -1.03
129S1/SvImJ m 0.175 0.0274   4 0.0137 0.157 0.146, 0.208 -0.38
A/J f 0.197 0.00727   4 0.00364 0.037 0.187, 0.204 -0.46
A/J m 0.17 0.0112   4 0.00561 0.0657 0.157, 0.182 -0.51
C57BL/6J f 0.203 0.0165   4 0.00826 0.0813 0.182, 0.222 -0.33
C57BL/6J m 0.168 0.00545   4 0.00272 0.0325 0.163, 0.175 -0.56
NOD/ShiLtJ f 0.273 0.0537   4 0.0268 0.197 0.217, 0.345 1.2
NOD/ShiLtJ m 0.212 0.0168   4 0.00842 0.0794 0.198, 0.235 0.57
NZO/HlLtJ f 0.278 0.0485   4 0.0242 0.174 0.237, 0.34 1.31
NZO/HlLtJ m 0.269 0.026   4 0.013 0.0966 0.236, 0.299 2.04
PWK/PhJ m 0.158 0.0   1   0.0 0.0 0.158, 0.158 -0.82
WSB/EiJ f 0.187 0.0   1   0.0 0.0 0.187, 0.187 -0.68
WSB/EiJ m 0.177 0.0278   3 0.016 0.157 0.147, 0.202 -0.33


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.1705 0.0137 0.1985 0.1425
129S1/SvImJ m 0.1748 0.0137 0.2027 0.1468
A/J f 0.1968 0.0137 0.2247 0.1688
A/J m 0.1705 0.0137 0.1985 0.1425
C57BL/6J f 0.2033 0.0137 0.2312 0.1753
C57BL/6J m 0.1675 0.0137 0.1955 0.1395
NOD/ShiLtJ f 0.2728 0.0137 0.3007 0.2448
NOD/ShiLtJ m 0.212 0.0137 0.24 0.184
NZO/HlLtJ f 0.278 0.0137 0.306 0.25
NZO/HlLtJ m 0.2688 0.0137 0.2967 0.2408


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.1726 0.0097 0.1924 0.1528
A/J both 0.1836 0.0097 0.2034 0.1638
C57BL/6J both 0.1854 0.0097 0.2052 0.1656
NOD/ShiLtJ both 0.2424 0.0097 0.2622 0.2226
NZO/HlLtJ both 0.2734 0.0097 0.2932 0.2536




  GWAS USING LINEAR MIXED MODELS