Project measure / variable:   GMC20   IgE_17

ID, description, units MPD:56914   IgE_17   immunoglobulin E (plasma IgE)   [ng/mL]  at age 16-17wks  
Data set, strains GMC20   inbred w/CC8   7 strains     sex: both     age: 16-17wks
Procedure immunoglobulin quantification
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  STRAIN COMPARISON PLOT
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GMC20 - immunoglobulin E (plasma IgE) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means675   ng/mL 186   ng/mL
Median of the strain means372   ng/mL 99.4   ng/mL
SD of the strain means± 716 ± 220
Coefficient of variation (CV)1.06 1.18
Min–max range of strain means31.5   –   1574   ng/mL 30.7   –   662   ng/mL
Mean sample size per strain3.5   mice 3.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3582142.201 3582142.201 7.9061 0.0086
strain 4 6687610.0875 1671902.5219 3.69 0.0147
sex:strain 4 2707125.0315 676781.2579 1.4937 0.229
Residuals 30 13592618.075 453087.2692


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1574.0 600.0   4 300.0 0.381 1095.0, 2384.0 1.26
129S1/SvImJ m 662.0 271.0   4 136.0 0.41 506.0, 1068.0 2.17
A/J f 584.0 264.0   4 132.0 0.452 349.0, 930.0 -0.13
A/J m 195.0 48.0   4 24.0 0.246 140.0, 240.0 0.04
C57BL/6J f 161.0 154.0   4 77.2 0.96 42.1, 374.0 -0.72
C57BL/6J m 30.7 19.0   4 9.5 0.619 9.0, 53.2 -0.7
NOD/ShiLtJ f 1560.0 1986.0   4 993.0 1.27 165.0, 4453.0 1.24
NOD/ShiLtJ m 99.4 54.2   4 27.1 0.546 54.5, 174.0 -0.39
NZO/HlLtJ f 138.0 236.0   4 118.0 1.71 11.3, 492.0 -0.75
NZO/HlLtJ m 37.4 14.3   4 7.16 0.383 18.2, 52.0 -0.67
PWK/PhJ m 187.0 0.0   1   0.0 0.0 187.0, 187.0 0.01
WSB/EiJ f 31.5 0.0   1   0.0 0.0 31.5, 31.5 -0.9
WSB/EiJ m 88.2 71.6   2   50.6 0.811 37.6, 139.0 -0.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1574.025 336.5588 2261.3697 886.6803
129S1/SvImJ m 661.5 336.5588 1348.8447 -25.8447
A/J f 583.725 336.5588 1271.0697 -103.6197
A/J m 195.2 336.5588 882.5447 -492.1447
C57BL/6J f 160.75 336.5588 848.0947 -526.5947
C57BL/6J m 30.7 336.5588 718.0447 -656.6447
NOD/ShiLtJ f 1560.15 336.5588 2247.4947 872.8053
NOD/ShiLtJ m 99.35 336.5588 786.6947 -587.9947
NZO/HlLtJ f 138.0 336.5588 825.3447 -549.3447
NZO/HlLtJ m 37.35 336.5588 724.6947 -649.9947


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1117.7625 237.983 1603.7886 631.7364
A/J both 389.4625 237.983 875.4886 -96.5636
C57BL/6J both 95.725 237.983 581.7511 -390.3011
NOD/ShiLtJ both 829.75 237.983 1315.7761 343.7239
NZO/HlLtJ both 87.675 237.983 573.7011 -398.3511




  GWAS USING LINEAR MIXED MODELS