Project measure / variable:   GMC18   bone_mass_wholebody

ID, description, units MPD:56736   bone_mass_wholebody   bone mass, whole body including head   [g]  
Data set, strains GMC18   inbred w/CC8   7 strains     sex: both     age: 17-18wks
Procedure DXA
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  STRAIN COMPARISON PLOT
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GMC18 - bone mass, whole body including head



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means0.701   g 0.700   g
Median of the strain means0.545   g 0.657   g
SD of the strain means± 0.426 ± 0.472
Coefficient of variation (CV)0.608 0.674
Min–max range of strain means0.438   –   1.56   g 0.331   –   1.71   g
Mean sample size per strain13.8   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.442 0.442 17.7444 < 0.0001
strain 4 29.2048 7.3012 293.1253 < 0.0001
sex:strain 4 0.1104 0.0276 1.1086 0.3546
Residuals 152 3.786 0.0249


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.619 0.0901   16 0.0225 0.145 0.398, 0.762 -0.19
129S1/SvImJ m 0.677 0.22   16 0.0551 0.325 0.246, 0.973 -0.05
A/J f 0.438 0.0997   16 0.0249 0.228 0.316, 0.632 -0.62
A/J m 0.46 0.118   16 0.0294 0.256 0.313, 0.667 -0.51
C57BL/6J f 0.498 0.105   16 0.0262 0.211 0.344, 0.664 -0.48
C57BL/6J m 0.657 0.0862   16 0.0216 0.131 0.484, 0.846 -0.09
CAST/EiJ m 0.331 0.0204   4 0.0102 0.0618 0.312, 0.352 -0.78
NOD/ShiLtJ f 0.593 0.0728   18 0.0172 0.123 0.418, 0.709 -0.25
NOD/ShiLtJ m 0.711 0.0997   16 0.0249 0.14 0.515, 0.865 0.02
NZO/HlLtJ f 1.56 0.0797   16 0.0199 0.0511 1.45, 1.75 2.02
NZO/HlLtJ m 1.71 0.362   16 0.0906 0.212 0.806, 2.13 2.14
WSB/EiJ f 0.498 0.0   1   0.0 0.0 0.498, 0.498 -0.48
WSB/EiJ m 0.353 0.0463   3 0.0267 0.131 0.323, 0.406 -0.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.6193 0.0395 0.6973 0.5414
129S1/SvImJ m 0.6774 0.0395 0.7554 0.5995
A/J f 0.438 0.0395 0.516 0.36
A/J m 0.4604 0.0395 0.5384 0.3825
C57BL/6J f 0.4978 0.0395 0.5757 0.4198
C57BL/6J m 0.657 0.0395 0.735 0.579
NOD/ShiLtJ f 0.5932 0.0372 0.6667 0.5197
NOD/ShiLtJ m 0.7106 0.0395 0.7886 0.6327
NZO/HlLtJ f 1.5596 0.0395 1.6376 1.4817
NZO/HlLtJ m 1.7066 0.0395 1.7846 1.6287


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.6484 0.0279 0.7035 0.5933
A/J both 0.4492 0.0279 0.5043 0.3941
C57BL/6J both 0.5774 0.0279 0.6325 0.5223
NOD/ShiLtJ both 0.6519 0.0271 0.7055 0.5983
NZO/HlLtJ both 1.6331 0.0279 1.6882 1.578




  GWAS USING LINEAR MIXED MODELS