Project measure / variable:   GMC18   bone_area_wholebody

ID, description, units MPD:56735   bone_area_wholebody   bone area, whole body including head   [cm2]  
Data set, strains GMC18   inbred w/CC8   7 strains     sex: both     age: 17-18wks
Procedure DXA
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  STRAIN COMPARISON PLOT
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GMC18 - bone area, whole body including head



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means10.8   cm2 10.6   cm2
Median of the strain means9.29   cm2 9.36   cm2
SD of the strain means± 5.02 ± 5.98
Coefficient of variation (CV)0.463 0.566
Min–max range of strain means7.24   –   20.8   cm2 5.51   –   22.8   cm2
Mean sample size per strain13.8   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 94.5675 94.5675 17.0143 0.0001
strain 4 4217.1219 1054.2805 189.6826 < 0.0001
sex:strain 4 46.5794 11.6448 2.0951 0.0842
Residuals 152 844.8356 5.5581


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 8.77 1.67   16 0.418 0.191 3.99, 10.5 -0.41
129S1/SvImJ m 9.36 3.14   16 0.785 0.336 4.29, 13.1 -0.2
A/J f 7.24 2.2   16 0.549 0.303 4.61, 11.2 -0.72
A/J m 7.45 2.65   16 0.663 0.356 4.47, 11.6 -0.52
C57BL/6J f 7.97 2.38   16 0.596 0.299 4.34, 11.5 -0.57
C57BL/6J m 11.2 1.8   16 0.449 0.16 6.62, 13.7 0.11
CAST/EiJ m 5.51 0.418   4 0.209 0.0759 4.96, 5.84 -0.84
NOD/ShiLtJ f 10.5 1.21   18 0.285 0.115 6.55, 12.1 -0.07
NOD/ShiLtJ m 12.1 1.9   16 0.474 0.157 7.66, 14.0 0.26
NZO/HlLtJ f 20.8 0.883   16 0.221 0.0426 19.8, 23.1 1.98
NZO/HlLtJ m 22.8 4.11   16 1.03 0.18 13.1, 27.2 2.05
WSB/EiJ f 9.8 0.0   1   0.0 0.0 9.8, 9.8 -0.21
WSB/EiJ m 5.51 0.688   3 0.397 0.125 5.04, 6.3 -0.84


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 8.7681 0.5894 9.9326 7.6037
129S1/SvImJ m 9.3599 0.5894 10.5244 8.1955
A/J f 7.2404 0.5894 8.4049 6.076
A/J m 7.4464 0.5894 8.6109 6.282
C57BL/6J f 7.9731 0.5894 9.1375 6.8086
C57BL/6J m 11.2219 0.5894 12.3863 10.0574
NOD/ShiLtJ f 10.5448 0.5557 11.6427 9.447
NOD/ShiLtJ m 12.0611 0.5894 13.2256 10.8967
NZO/HlLtJ f 20.7584 0.5894 21.9229 19.594
NZO/HlLtJ m 22.774 0.5894 23.9385 21.6095


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 9.064 0.4168 9.8874 8.2406
A/J both 7.3434 0.4168 8.1668 6.52
C57BL/6J both 9.5975 0.4168 10.4209 8.7741
NOD/ShiLtJ both 11.303 0.405 12.1032 10.5028
NZO/HlLtJ both 21.7662 0.4168 22.5896 20.9428




  GWAS USING LINEAR MIXED MODELS