Project measure / variable:   GMC18   SOFTmass_wholebody

ID, description, units MPD:56734   SOFTmass_wholebody   total soft tissue mass, whole body including head   [g]  
Data set, strains GMC18   inbred w/CC8   7 strains     sex: both     age: 17-18wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC18 - total soft tissue mass, whole body including head



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means24.5   g 27.2   g
Median of the strain means20.1   g 24.9   g
SD of the strain means± 11.9 ± 11.8
Coefficient of variation (CV)0.488 0.434
Min–max range of strain means17.2   –   48.6   g 16.7   –   51.6   g
Mean sample size per strain13.8   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1225.5008 1225.5008 127.8083 < 0.0001
strain 4 18907.2684 4726.8171 492.963 < 0.0001
sex:strain 4 135.627 33.9067 3.5362 0.0086
Residuals 152 1457.4646 9.5886


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 20.2 1.59   16 0.398 0.079 16.9, 23.0 -0.36
129S1/SvImJ m 24.9 2.91   16 0.729 0.117 19.0, 30.3 -0.19
A/J f 18.7 1.12   16 0.28 0.0599 16.6, 20.3 -0.48
A/J m 23.0 1.47   16 0.366 0.0638 20.9, 26.4 -0.36
C57BL/6J f 20.1 1.43   16 0.358 0.0712 18.2, 22.6 -0.37
C57BL/6J m 28.0 1.41   16 0.354 0.0505 25.7, 30.1 0.07
CAST/EiJ m 16.7 0.523   4 0.261 0.0314 16.1, 17.3 -0.89
NOD/ShiLtJ f 22.0 2.43   18 0.574 0.111 16.0, 25.2 -0.21
NOD/ShiLtJ m 29.1 2.33   16 0.582 0.0801 26.8, 34.3 0.16
NZO/HlLtJ f 48.6 3.6   16 0.901 0.0742 42.3, 56.3 2.02
NZO/HlLtJ m 51.6 7.32   16 1.83 0.142 34.8, 61.3 2.07
WSB/EiJ f 17.2 0.0   1   0.0 0.0 17.2, 17.2 -0.61
WSB/EiJ m 17.1 0.488   3 0.282 0.0286 16.6, 17.6 -0.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 20.1864 0.7741 21.7159 18.657
129S1/SvImJ m 24.8586 0.7741 26.3881 23.3292
A/J f 18.7326 0.7741 20.262 17.2031
A/J m 22.9797 0.7741 24.5091 21.4502
C57BL/6J f 20.0894 0.7741 21.6189 18.56
C57BL/6J m 28.015 0.7741 29.5445 26.4855
NOD/ShiLtJ f 21.9551 0.7299 23.397 20.5131
NOD/ShiLtJ m 29.0878 0.7741 30.6173 27.5584
NZO/HlLtJ f 48.5915 0.7741 50.121 47.062
NZO/HlLtJ m 51.6377 0.7741 53.1672 50.1083


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 22.5225 0.5474 23.604 21.441
A/J both 20.8561 0.5474 21.9376 19.7746
C57BL/6J both 24.0522 0.5474 25.1337 22.9707
NOD/ShiLtJ both 25.5214 0.532 26.5725 24.4704
NZO/HlLtJ both 50.1146 0.5474 51.1961 49.0331




  GWAS USING LINEAR MIXED MODELS