Project measure / variable:   GMC18   BMD_wholebody

ID, description, units MPD:56731   BMD_wholebody   bone mineral density (BMD), whole body including head   [g/cm2]  
Data set, strains GMC18   inbred w/CC8   7 strains     sex: both     age: 17-18wks
Procedure DXA
Ontology mappings

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  STRAIN COMPARISON PLOT
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GMC18 - bone mineral density (BMD), whole body including head



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means0.0635   g/cm2 0.0647   g/cm2
Median of the strain means0.0631   g/cm2 0.0637   g/cm2
SD of the strain means± 0.00916 ± 0.00636
Coefficient of variation (CV)0.144 0.0982
Min–max range of strain means0.0510   –   0.0751   g/cm2 0.0591   –   0.0744   g/cm2
Mean sample size per strain13.8   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0 0.0 0.0122 0.9122
strain 4 0.007 0.0018 46.9281 < 0.0001
sex:strain 4 0.0003 0.0001 2.2214 0.0693
Residuals 152 0.0057 0.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0721 0.00995   16 0.00249 0.138 0.062, 0.1 0.94
129S1/SvImJ m 0.0727 0.00666   16 0.00167 0.0916 0.057, 0.083 1.26
A/J f 0.0619 0.00691   16 0.00173 0.112 0.049, 0.071 -0.17
A/J m 0.0638 0.00636   16 0.00159 0.0996 0.052, 0.071 -0.14
C57BL/6J f 0.0644 0.00786   16 0.00196 0.122 0.055, 0.079 0.1
C57BL/6J m 0.0591 0.00552   16 0.00138 0.0934 0.05, 0.073 -0.88
CAST/EiJ m 0.06 0.00216   4 0.00108 0.036 0.058, 0.063 -0.74
NOD/ShiLtJ f 0.0563 0.00346   18 0.000816 0.0615 0.051, 0.064 -0.78
NOD/ShiLtJ m 0.0593 0.00401   16 0.001 0.0677 0.054, 0.069 -0.85
NZO/HlLtJ f 0.0751 0.00171   16 0.000427 0.0227 0.071, 0.078 1.27
NZO/HlLtJ m 0.0744 0.0047   16 0.00118 0.0632 0.061, 0.081 1.52
WSB/EiJ f 0.051 0.0   1   0.0 0.0 0.051, 0.051 -1.36
WSB/EiJ m 0.0637 0.00153   3 0.000882 0.024 0.062, 0.065 -0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0721 0.0015 0.0751 0.0691
129S1/SvImJ m 0.0727 0.0015 0.0757 0.0697
A/J f 0.0619 0.0015 0.065 0.0589
A/J m 0.0638 0.0015 0.0668 0.0608
C57BL/6J f 0.0644 0.0015 0.0674 0.0614
C57BL/6J m 0.0591 0.0015 0.0621 0.056
NOD/ShiLtJ f 0.0563 0.0014 0.0592 0.0535
NOD/ShiLtJ m 0.0592 0.0015 0.0623 0.0562
NZO/HlLtJ f 0.0751 0.0015 0.0781 0.0721
NZO/HlLtJ m 0.0744 0.0015 0.0775 0.0714


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0724 0.0011 0.0745 0.0703
A/J both 0.0629 0.0011 0.065 0.0607
C57BL/6J both 0.0617 0.0011 0.0639 0.0596
NOD/ShiLtJ both 0.0578 0.001 0.0599 0.0557
NZO/HlLtJ both 0.0748 0.0011 0.0769 0.0726




  GWAS USING LINEAR MIXED MODELS