Project measure / variable:   GMC18   bone_mass_Xhead

ID, description, units MPD:56726   bone_mass_Xhead   bone mass, without head   [g]  
Data set, strains GMC18   inbred w/CC8   7 strains     sex: both     age: 17-18wks
Procedure DXA
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC18 - bone mass, without head



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means0.472   g 0.479   g
Median of the strain means0.348   g 0.431   g
SD of the strain means± 0.350 ± 0.390
Coefficient of variation (CV)0.742 0.815
Min–max range of strain means0.278   –   1.18   g 0.194   –   1.32   g
Mean sample size per strain13.8   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3556 0.3556 19.1835 < 0.0001
strain 4 20.2208 5.0552 272.7447 < 0.0001
sex:strain 4 0.1192 0.0298 1.6074 0.1752
Residuals 152 2.8173 0.0185


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.378 0.0768   16 0.0192 0.203 0.177, 0.492 -0.27
129S1/SvImJ m 0.448 0.16   16 0.04 0.357 0.21, 0.666 -0.08
A/J f 0.278 0.102   16 0.0256 0.368 0.157, 0.508 -0.55
A/J m 0.275 0.1   16 0.0251 0.364 0.159, 0.451 -0.52
C57BL/6J f 0.288 0.0888   16 0.0222 0.309 0.157, 0.429 -0.53
C57BL/6J m 0.431 0.0712   16 0.0178 0.165 0.277, 0.588 -0.12
CAST/EiJ m 0.194 0.0203   4 0.0101 0.104 0.177, 0.216 -0.73
NOD/ShiLtJ f 0.39 0.0617   18 0.0145 0.158 0.235, 0.494 -0.23
NOD/ShiLtJ m 0.491 0.0899   16 0.0225 0.183 0.314, 0.633 0.03
NZO/HlLtJ f 1.18 0.0734   16 0.0184 0.0623 1.07, 1.35 2.02
NZO/HlLtJ m 1.32 0.324   16 0.081 0.245 0.531, 1.7 2.15
WSB/EiJ f 0.317 0.0   1   0.0 0.0 0.317, 0.317 -0.44
WSB/EiJ m 0.195 0.039   3 0.0225 0.2 0.171, 0.24 -0.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3783 0.034 0.4456 0.3111
129S1/SvImJ m 0.4481 0.034 0.5154 0.3809
A/J f 0.2782 0.034 0.3454 0.2109
A/J m 0.2754 0.034 0.3426 0.2081
C57BL/6J f 0.2876 0.034 0.3548 0.2203
C57BL/6J m 0.4312 0.034 0.4984 0.3639
NOD/ShiLtJ f 0.3903 0.0321 0.4537 0.3269
NOD/ShiLtJ m 0.4908 0.034 0.558 0.4235
NZO/HlLtJ f 1.1778 0.034 1.245 1.1105
NZO/HlLtJ m 1.3215 0.034 1.3887 1.2543


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.4132 0.0241 0.4608 0.3657
A/J both 0.2768 0.0241 0.3243 0.2292
C57BL/6J both 0.3594 0.0241 0.4069 0.3118
NOD/ShiLtJ both 0.4405 0.0234 0.4867 0.3943
NZO/HlLtJ both 1.2496 0.0241 1.2972 1.2021




  GWAS USING LINEAR MIXED MODELS