Project measure / variable:   GMC18   bone_area_Xhead

ID, description, units MPD:56725   bone_area_Xhead   bone area, without head   [cm2]  
Data set, strains GMC18   inbred w/CC8   7 strains     sex: both     age: 17-18wks
Procedure DXA
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  STRAIN COMPARISON PLOT
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GMC18 - bone area, without head



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means8.69   cm2 8.43   cm2
Median of the strain means7.24   cm2 7.42   cm2
SD of the strain means± 4.69 ± 5.58
Coefficient of variation (CV)0.540 0.662
Min–max range of strain means5.52   –   18.0   cm2 3.75   –   19.9   cm2
Mean sample size per strain13.8   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 84.3412 84.3412 17.3211 0.0001
strain 4 3734.9036 933.7259 191.7581 < 0.0001
sex:strain 4 43.988 10.997 2.2584 0.0654
Residuals 152 740.1321 4.8693


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 6.64 1.57   16 0.393 0.237 2.21, 8.36 -0.44
129S1/SvImJ m 7.42 2.71   16 0.678 0.366 3.47, 10.8 -0.18
A/J f 5.52 2.19   16 0.548 0.397 2.85, 9.02 -0.68
A/J m 5.47 2.44   16 0.611 0.447 2.9, 9.37 -0.53
C57BL/6J f 5.85 2.21   16 0.553 0.378 2.52, 9.09 -0.61
C57BL/6J m 8.92 1.68   16 0.421 0.189 4.61, 11.3 0.09
CAST/EiJ m 3.79 0.424   4 0.212 0.112 3.29, 4.16 -0.83
NOD/ShiLtJ f 8.27 1.13   18 0.266 0.136 4.59, 9.8 -0.09
NOD/ShiLtJ m 9.75 1.84   16 0.461 0.189 5.43, 11.6 0.24
NZO/HlLtJ f 18.0 0.858   16 0.215 0.0476 17.1, 20.3 1.99
NZO/HlLtJ m 19.9 3.93   16 0.982 0.197 10.7, 24.2 2.06
WSB/EiJ f 7.85 0.0   1   0.0 0.0 7.85, 7.85 -0.18
WSB/EiJ m 3.75 0.612   3 0.353 0.163 3.31, 4.45 -0.84


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 6.639 0.5517 7.7289 5.5491
129S1/SvImJ m 7.4174 0.5517 8.5073 6.3275
A/J f 5.5212 0.5517 6.6111 4.4313
A/J m 5.4729 0.5517 6.5629 4.383
C57BL/6J f 5.8477 0.5517 6.9376 4.7578
C57BL/6J m 8.9182 0.5517 10.0081 7.8283
NOD/ShiLtJ f 8.2747 0.5201 9.3022 7.2471
NOD/ShiLtJ m 9.7457 0.5517 10.8356 8.6558
NZO/HlLtJ f 18.0439 0.5517 19.1338 16.954
NZO/HlLtJ m 19.9162 0.5517 21.0061 18.8263


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.0282 0.3901 7.7989 6.2575
A/J both 5.4971 0.3901 6.2677 4.7264
C57BL/6J both 7.3829 0.3901 8.1536 6.6123
NOD/ShiLtJ both 9.0102 0.3791 9.7591 8.2612
NZO/HlLtJ both 18.98 0.3901 19.7507 18.2093




  GWAS USING LINEAR MIXED MODELS