Project measure / variable:   GMC16   urea_17

ID, description, units MPD:56544   urea_17   blood urea nitrogen (plasma BUN)   [mmol/L]  at age 16-17wks  
Data set, strains GMC16   inbred w/CC8   7 strains     sex: both     age: 16-17wks
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  STRAIN COMPARISON PLOT
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GMC16 - blood urea nitrogen (plasma BUN) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means9.98   mmol/L 11.3   mmol/L
Median of the strain means9.84   mmol/L 11.0   mmol/L
SD of the strain means± 1.63 ± 2.11
Coefficient of variation (CV)0.163 0.186
Min–max range of strain means8.04   –   12.7   mmol/L 9.48   –   15.8   mmol/L
Mean sample size per strain3.5   mice 3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.2231 2.2231 1.1943 0.2832
strain 4 47.3327 11.8332 6.3571 0.0008
sex:strain 4 18.3343 4.5836 2.4624 0.0666
Residuals 30 55.8422 1.8614


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 8.04 0.435   4 0.217 0.0541 7.53, 8.44 -1.19
129S1/SvImJ m 9.77 0.988   4 0.494 0.101 8.84, 11.1 -0.74
A/J f 8.73 1.3   4 0.65 0.149 7.49, 10.5 -0.76
A/J m 9.48 0.594   4 0.297 0.0627 8.69, 9.96 -0.88
C57BL/6J f 10.7 0.736   4 0.368 0.0686 9.92, 11.7 0.44
C57BL/6J m 11.6 1.02   4 0.51 0.0882 10.4, 12.6 0.13
NOD/ShiLtJ f 12.7 3.22   4 1.61 0.253 9.17, 17.0 1.67
NOD/ShiLtJ m 10.6 0.582   4 0.291 0.0551 10.0, 11.3 -0.35
NZO/HlLtJ f 9.92 0.471   4 0.236 0.0475 9.36, 10.5 -0.03
NZO/HlLtJ m 11.1 1.71   4 0.853 0.154 9.46, 13.2 -0.11
PWK/PhJ m 15.8 0.0   1   0.0 0.0 15.8, 15.8 2.12
WSB/EiJ f 9.76 0.0   1   0.0 0.0 9.76, 9.76 -0.13
WSB/EiJ m 11.0 1.23   3 0.711 0.112 10.1, 12.4 -0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 8.04 0.6822 9.4332 6.6468
129S1/SvImJ m 9.7675 0.6822 11.1607 8.3743
A/J f 8.73 0.6822 10.1232 7.3368
A/J m 9.475 0.6822 10.8682 8.0818
C57BL/6J f 10.725 0.6822 12.1182 9.3318
C57BL/6J m 11.565 0.6822 12.9582 10.1718
NOD/ShiLtJ f 12.7075 0.6822 14.1007 11.3143
NOD/ShiLtJ m 10.56 0.6822 11.9532 9.1668
NZO/HlLtJ f 9.9225 0.6822 11.3157 8.5293
NZO/HlLtJ m 11.115 0.6822 12.5082 9.7218


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.9037 0.4824 9.8889 7.9186
A/J both 9.1025 0.4824 10.0876 8.1174
C57BL/6J both 11.145 0.4824 12.1301 10.1599
NOD/ShiLtJ both 11.6337 0.4824 12.6189 10.6486
NZO/HlLtJ both 10.5187 0.4824 11.5039 9.5336




  GWAS USING LINEAR MIXED MODELS