Project measure / variable:   GMC16   total_protein_21

ID, description, units MPD:56543   total_protein_21   total protein (plasma TP)   [g/L]  at age 20-21wks  
Data set, strains GMC16   inbred w/CC8   8 strains     sex: both     age: 20-21wks
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  STRAIN COMPARISON PLOT
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GMC16 - total protein (plasma TP) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means49.1   g/L 50.1   g/L
Median of the strain means49.8   g/L 51.1   g/L
SD of the strain means± 3.66 ± 3.75
Coefficient of variation (CV)0.0745 0.0748
Min–max range of strain means44.6   –   54.3   g/L 43.7   –   54.4   g/L
Mean sample size per strain10.0   mice 11.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 52.9002 52.9002 7.1524 0.0083
strain 7 1917.9931 273.999 37.0462 < 0.0001
sex:strain 7 193.2441 27.6063 3.7325 0.0009
Residuals 157 1161.194 7.3961


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 51.7 1.17   10 0.371 0.0227 49.5, 53.4 0.72
129S1/SvImJ m 53.6 2.64   12 0.762 0.0492 48.7, 59.8 0.94
A/J f 49.9 1.75   10 0.555 0.0352 47.3, 52.8 0.23
A/J m 50.7 1.9   11 0.574 0.0375 48.4, 53.3 0.17
C57BL/6J f 51.9 1.81   10 0.571 0.0348 49.4, 54.8 0.77
C57BL/6J m 52.2 2.29   12 0.661 0.0439 48.5, 55.5 0.57
CAST/EiJ f 44.6 2.08   12 0.601 0.0467 41.8, 48.2 -1.22
CAST/EiJ m 45.9 1.98   11 0.597 0.0431 43.2, 49.3 -1.11
NOD/ShiLtJ f 45.4 6.76   8 2.39 0.149 37.0, 55.8 -1.01
NOD/ShiLtJ m 51.5 2.78   12 0.802 0.054 45.9, 54.5 0.38
NZO/HlLtJ f 54.3 2.17   10 0.687 0.04 50.7, 56.8 1.43
NZO/HlLtJ m 54.4 4.13   12 1.19 0.0759 47.2, 60.6 1.15
PWK/PhJ f 49.8 2.64   10 0.835 0.053 46.5, 53.6 0.2
PWK/PhJ m 48.6 3.02   11 0.912 0.0623 44.0, 53.3 -0.39
WSB/EiJ f 45.0 1.55   10 0.49 0.0345 41.3, 47.5 -1.11
WSB/EiJ m 43.7 1.45   12 0.419 0.0332 40.6, 46.0 -1.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 51.67 0.86 53.3687 49.9713
129S1/SvImJ m 53.6083 0.7851 55.159 52.0577
A/J f 49.87 0.86 51.5687 48.1713
A/J m 50.7273 0.82 52.3469 49.1076
C57BL/6J f 51.92 0.86 53.6187 50.2213
C57BL/6J m 52.2 0.7851 53.7507 50.6493
CAST/EiJ f 44.5583 0.7851 46.109 43.0077
CAST/EiJ m 45.9364 0.82 47.556 44.3167
NOD/ShiLtJ f 45.375 0.9615 47.2742 43.4758
NOD/ShiLtJ m 51.5167 0.7851 53.0673 49.966
NZO/HlLtJ f 54.27 0.86 55.9687 52.5713
NZO/HlLtJ m 54.45 0.7851 56.0007 52.8993
PWK/PhJ f 49.79 0.86 51.4887 48.0913
PWK/PhJ m 48.5545 0.82 50.1742 46.9349
WSB/EiJ f 44.99 0.86 46.6887 43.2913
WSB/EiJ m 43.725 0.7851 45.2757 42.1743


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 52.6392 0.5822 53.7892 51.4892
A/J both 50.2986 0.5941 51.4722 49.1251
C57BL/6J both 52.06 0.5822 53.21 50.91
CAST/EiJ both 45.2473 0.5676 46.3685 44.1262
NOD/ShiLtJ both 48.4458 0.6207 49.6717 47.2199
NZO/HlLtJ both 54.36 0.5822 55.51 53.21
PWK/PhJ both 49.1723 0.5941 50.3458 47.9987
WSB/EiJ both 44.3575 0.5822 45.5075 43.2075




  GWAS USING LINEAR MIXED MODELS