Project measure / variable:   GMC16   creatinine_17

ID, description, units MPD:56540   creatinine_17   creatinine (plasma)   [µmol/L]  at age 16-17wks  
Data set, strains GMC16   inbred w/CC8   7 strains     sex: both     age: 16-17wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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GMC16 - creatinine (plasma) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means13.2   µmol/L 12.5   µmol/L
Median of the strain means13.2   µmol/L 12.4   µmol/L
SD of the strain means± 2.00 ± 3.13
Coefficient of variation (CV)0.152 0.251
Min–max range of strain means9.90   –   16.2   µmol/L 8.75   –   15.9   µmol/L
Mean sample size per strain3.3   mice 3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2831 0.2831 0.0964 0.7584
strain 4 95.1474 23.7869 8.1007 0.0002
sex:strain 4 115.7339 28.9335 9.8534 < 0.0001
Residuals 29 85.1551 2.9364


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 13.3 2.11   4 1.06 0.159 11.3, 15.9 0.04
129S1/SvImJ m 15.2 0.72   4 0.36 0.0474 14.2, 15.8 0.88
A/J f 13.1 1.42   4 0.709 0.109 11.2, 14.7 -0.06
A/J m 12.4 0.842   4 0.421 0.068 11.5, 13.3 -0.02
C57BL/6J f 16.2 1.35   4 0.677 0.0834 14.3, 17.5 1.49
C57BL/6J m 15.5 1.04   4 0.52 0.0672 14.4, 16.8 0.97
NOD/ShiLtJ f 9.9 1.73   3 0.997 0.174 8.22, 11.7 -1.66
NOD/ShiLtJ m 15.9 2.02   4 1.01 0.127 14.0, 18.6 1.1
NZO/HlLtJ f 13.6 0.379   4 0.19 0.0279 13.2, 14.1 0.19
NZO/HlLtJ m 8.86 3.4   4 1.7 0.383 4.95, 12.6 -1.15
PWK/PhJ m 8.75 0.0   1   0.0 0.0 8.75, 8.75 -1.18
WSB/EiJ f 13.2 0.0   1   0.0 0.0 13.2, 13.2 -0.01
WSB/EiJ m 10.6 1.38   3 0.798 0.13 9.37, 12.1 -0.59


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 13.285 0.8568 15.0373 11.5327
129S1/SvImJ m 15.1825 0.8568 16.9348 13.4302
A/J f 13.0625 0.8568 14.8148 11.3102
A/J m 12.3775 0.8568 14.1298 10.6252
C57BL/6J f 16.2425 0.8568 17.9948 14.4902
C57BL/6J m 15.4725 0.8568 17.2248 13.7202
NOD/ShiLtJ f 9.9 0.9893 11.9234 7.8766
NOD/ShiLtJ m 15.9125 0.8568 17.6648 14.1602
NZO/HlLtJ f 13.5925 0.8568 15.3448 11.8402
NZO/HlLtJ m 8.8625 0.8568 10.6148 7.1102


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 14.2338 0.6058 15.4728 12.9947
A/J both 12.72 0.6058 13.9591 11.4809
C57BL/6J both 15.8575 0.6058 17.0966 14.6184
NOD/ShiLtJ both 12.9062 0.6544 14.2446 11.5679
NZO/HlLtJ both 11.2275 0.6058 12.4666 9.9884




  GWAS USING LINEAR MIXED MODELS