Project measure / variable:   GMC16   GLU_21

ID, description, units MPD:56537   GLU_21   glucose (plasma GLU)   [mmol/L]  at age 20-21wks  
Data set, strains GMC16   inbred w/CC8   8 strains     sex: both     age: 20-21wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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GMC16 - glucose (plasma GLU) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means15.1   mmol/L 15.1   mmol/L
Median of the strain means13.4   mmol/L 14.8   mmol/L
SD of the strain means± 5.78 ± 4.14
Coefficient of variation (CV)0.384 0.274
Min–max range of strain means10.9   –   28.4   mmol/L 10.2   –   23.7   mmol/L
Mean sample size per strain10.1   mice 11.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.8708 0.8708 0.0187 0.8915
strain 7 1919.8708 274.2673 5.8836 < 0.0001
sex:strain 7 1666.9937 238.142 5.1086 < 0.0001
Residuals 158 7365.289 46.6158


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.9 1.79   10 0.564 0.164 7.25, 13.4 -0.72
129S1/SvImJ m 10.2 1.5   12 0.433 0.147 6.48, 12.8 -1.18
A/J f 12.3 2.51   10 0.794 0.203 6.43, 14.6 -0.48
A/J m 11.6 2.03   11 0.611 0.175 6.55, 13.5 -0.84
C57BL/6J f 14.5 1.57   10 0.496 0.108 12.4, 17.0 -0.1
C57BL/6J m 14.6 1.74   12 0.502 0.119 10.9, 17.0 -0.11
CAST/EiJ f 16.8 1.7   12 0.491 0.101 13.9, 20.8 0.3
CAST/EiJ m 17.2 1.71   11 0.515 0.0993 13.1, 19.4 0.51
NOD/ShiLtJ f 28.4 19.0   9 6.34 0.67 6.27, 53.6 2.31
NOD/ShiLtJ m 15.3 13.5   12 3.91 0.883 3.52, 55.3 0.05
NZO/HlLtJ f 11.9 2.57   10 0.813 0.216 8.27, 16.4 -0.55
NZO/HlLtJ m 23.7 13.4   12 3.87 0.566 6.88, 50.7 2.09
PWK/PhJ f 14.8 1.48   10 0.469 0.0999 11.9, 16.9 -0.05
PWK/PhJ m 15.1 2.52   11 0.759 0.167 11.2, 18.4 0.01
WSB/EiJ f 10.9 1.06   10 0.336 0.0977 9.52, 12.6 -0.72
WSB/EiJ m 12.9 2.27   12 0.654 0.176 7.53, 15.4 -0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.864 2.1591 15.1284 6.5996
129S1/SvImJ m 10.1967 1.971 14.0895 6.3039
A/J f 12.343 2.1591 16.6074 8.0786
A/J m 11.5827 2.0586 15.6486 7.5168
C57BL/6J f 14.506 2.1591 18.7704 10.2416
C57BL/6J m 14.6192 1.971 18.512 10.7264
CAST/EiJ f 16.8192 1.971 20.712 12.9264
CAST/EiJ m 17.1964 2.0586 21.2623 13.1305
NOD/ShiLtJ f 28.3833 2.2759 32.8784 23.8883
NOD/ShiLtJ m 15.3183 1.971 19.2111 11.4255
NZO/HlLtJ f 11.89 2.1591 16.1544 7.6256
NZO/HlLtJ m 23.7067 1.971 27.5995 19.8139
PWK/PhJ f 14.836 2.1591 19.1004 10.5716
PWK/PhJ m 15.0964 2.0586 19.1623 11.0305
WSB/EiJ f 10.888 2.1591 15.1524 6.6236
WSB/EiJ m 12.8633 1.971 16.7561 8.9705


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 10.5303 1.4617 13.4173 7.6433
A/J both 11.9629 1.4916 14.9089 9.0168
C57BL/6J both 14.5626 1.4617 17.4496 11.6756
CAST/EiJ both 17.0078 1.425 19.8223 14.1933
NOD/ShiLtJ both 21.8508 1.5053 24.824 18.8777
NZO/HlLtJ both 17.7983 1.4617 20.6853 14.9113
PWK/PhJ both 14.9662 1.4916 17.9122 12.0202
WSB/EiJ both 11.8757 1.4617 14.7627 8.9887




  GWAS USING LINEAR MIXED MODELS