Project measure / variable:   GMC16   amylase_21

ID, description, units MPD:56535   amylase_21   alpha-amylase (plasma)   [IU/L]  at age 20-21wks  
Data set, strains GMC16   inbred w/CC8   8 strains     sex: both     age: 20-21wks
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  STRAIN COMPARISON PLOT
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GMC16 - alpha-amylase (plasma) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means622   IU/L 696   IU/L
Median of the strain means564   IU/L 696   IU/L
SD of the strain means± 180 ± 170
Coefficient of variation (CV)0.289 0.245
Min–max range of strain means446   –   957   IU/L 503   –   924   IU/L
Mean sample size per strain10.1   mice 11.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 284131.3036 284131.3036 31.9527 < 0.0001
strain 7 4337115.1409 619587.8773 69.6772 < 0.0001
sex:strain 7 330893.5393 47270.5056 5.3159 < 0.0001
Residuals 158 1404977.1587 8892.2605


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 829.0 66.3   10 21.0 0.08 728.0, 932.0 1.15
129S1/SvImJ m 924.0 81.1   12 23.4 0.0877 754.0, 1060.0 1.34
A/J f 543.0 53.3   10 16.8 0.0981 469.0, 660.0 -0.44
A/J m 555.0 37.9   11 11.4 0.0683 501.0, 625.0 -0.83
C57BL/6J f 627.0 37.2   10 11.8 0.0594 575.0, 676.0 0.03
C57BL/6J m 768.0 81.3   12 23.5 0.106 599.0, 872.0 0.42
CAST/EiJ f 487.0 84.9   12 24.5 0.174 398.0, 708.0 -0.75
CAST/EiJ m 623.0 55.7   11 16.8 0.0894 544.0, 707.0 -0.43
NOD/ShiLtJ f 586.0 143.0   9 47.8 0.245 386.0, 801.0 -0.2
NOD/ShiLtJ m 807.0 198.0   12 57.1 0.245 477.0, 1232.0 0.65
NZO/HlLtJ f 957.0 70.7   10 22.4 0.0739 851.0, 1078.0 1.86
NZO/HlLtJ m 883.0 167.0   12 48.3 0.189 522.0, 1151.0 1.1
PWK/PhJ f 446.0 45.4   10 14.4 0.102 406.0, 530.0 -0.98
PWK/PhJ m 503.0 63.1   11 19.0 0.126 428.0, 669.0 -1.13
WSB/EiJ f 503.0 60.9   10 19.3 0.121 428.0, 589.0 -0.66
WSB/EiJ m 505.0 41.6   12 12.0 0.0822 426.0, 551.0 -1.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 828.879 29.8199 887.776 769.982
129S1/SvImJ m 924.0733 27.2217 977.8387 870.3079
A/J f 543.109 29.8199 602.006 484.212
A/J m 554.7045 28.4322 610.8607 498.5484
C57BL/6J f 626.687 29.8199 685.584 567.79
C57BL/6J m 768.2875 27.2217 822.0529 714.5221
CAST/EiJ f 486.8275 27.2217 540.5929 433.0621
CAST/EiJ m 623.1582 28.4322 679.3143 567.0021
NOD/ShiLtJ f 585.6611 31.4329 647.744 523.5782
NOD/ShiLtJ m 806.5167 27.2217 860.2821 752.7513
NZO/HlLtJ f 957.195 29.8199 1016.092 898.298
NZO/HlLtJ m 882.7308 27.2217 936.4962 828.9654
PWK/PhJ f 446.326 29.8199 505.223 387.429
PWK/PhJ m 502.9364 28.4322 559.0925 446.7802
WSB/EiJ f 503.244 29.8199 562.141 444.347
WSB/EiJ m 505.4592 27.2217 559.2246 451.6938


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 876.4762 20.1882 916.3496 836.6027
A/J both 548.9068 20.6011 589.5957 508.2178
C57BL/6J both 697.4872 20.1882 737.3607 657.6138
CAST/EiJ both 554.9928 19.6813 593.8652 516.1205
NOD/ShiLtJ both 696.0889 20.7909 737.1529 655.0249
NZO/HlLtJ both 919.9629 20.1882 959.8364 880.0894
PWK/PhJ both 474.6312 20.6011 515.3202 433.9422
WSB/EiJ both 504.3516 20.1882 544.2251 464.4781




  GWAS USING LINEAR MIXED MODELS