Project measure / variable:   GMC16   amylase_17

ID, description, units MPD:56534   amylase_17   alpha-amylase (plasma)   [IU/L]  at age 16-17wks  
Data set, strains GMC16   inbred w/CC8   7 strains     sex: both     age: 16-17wks
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  STRAIN COMPARISON PLOT
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GMC16 - alpha-amylase (plasma) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means529   IU/L 600   IU/L
Median of the strain means527   IU/L 655   IU/L
SD of the strain means± 126 ± 158
Coefficient of variation (CV)0.237 0.263
Min–max range of strain means398   –   716   IU/L 332   –   753   IU/L
Mean sample size per strain3.5   mice 3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 44822.3555 44822.3555 6.5543 0.0157
strain 4 397421.4255 99355.3564 14.5287 < 0.0001
sex:strain 4 41432.5788 10358.1447 1.5147 0.223
Residuals 30 205157.2611 6838.5754


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 580.0 39.3   4 19.6 0.0678 537.0, 616.0 0.4
129S1/SvImJ m 675.0 32.0   4 16.0 0.0475 629.0, 703.0 0.48
A/J f 404.0 11.1   4 5.56 0.0275 394.0, 420.0 -1.0
A/J m 436.0 16.1   4 8.03 0.0368 414.0, 451.0 -1.04
C57BL/6J f 474.0 15.4   4 7.72 0.0326 456.0, 491.0 -0.44
C57BL/6J m 655.0 51.9   4 25.9 0.0792 601.0, 706.0 0.35
NOD/ShiLtJ f 603.0 144.0   4 72.0 0.239 484.0, 793.0 0.59
NOD/ShiLtJ m 611.0 47.2   4 23.6 0.0773 546.0, 648.0 0.07
NZO/HlLtJ f 716.0 13.1   4 6.55 0.0183 697.0, 727.0 1.49
NZO/HlLtJ m 736.0 198.0   4 99.2 0.269 473.0, 894.0 0.86
PWK/PhJ m 753.0 0.0   1   0.0 0.0 753.0, 753.0 0.97
WSB/EiJ f 398.0 0.0   1   0.0 0.0 398.0, 398.0 -1.04
WSB/EiJ m 332.0 47.5   3 27.4 0.143 292.0, 384.0 -1.7


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 579.6075 41.3478 664.0511 495.1639
129S1/SvImJ m 674.6475 41.3478 759.0911 590.2039
A/J f 404.325 41.3478 488.7686 319.8814
A/J m 435.9625 41.3478 520.4061 351.5189
C57BL/6J f 474.19 41.3478 558.6336 389.7464
C57BL/6J m 654.83 41.3478 739.2736 570.3864
NOD/ShiLtJ f 603.38 41.3478 687.8236 518.9364
NOD/ShiLtJ m 610.5025 41.3478 694.9461 526.0589
NZO/HlLtJ f 715.9225 41.3478 800.3661 631.4789
NZO/HlLtJ m 736.23 41.3478 820.6736 651.7864


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 627.1275 29.2373 686.8381 567.4169
A/J both 420.1437 29.2373 479.8544 360.4331
C57BL/6J both 564.51 29.2373 624.2206 504.7994
NOD/ShiLtJ both 606.9412 29.2373 666.6519 547.2306
NZO/HlLtJ both 726.0763 29.2373 785.7869 666.3656




  GWAS USING LINEAR MIXED MODELS