Project measure / variable:   GMC16   sodium_17

ID, description, units MPD:56524   sodium_17   sodium (plasma Na)   [mmol/L]  at age 16-17wks  
Data set, strains GMC16   inbred w/CC8   7 strains     sex: both     age: 16-17wks
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  STRAIN COMPARISON PLOT
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GMC16 - sodium (plasma Na) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means145   mmol/L 146   mmol/L
Median of the strain means146   mmol/L 147   mmol/L
SD of the strain means± 3.66 ± 3.35
Coefficient of variation (CV)0.0252 0.0229
Min–max range of strain means140   –   149   mmol/L 140   –   150   mmol/L
Mean sample size per strain3.3   mice 3.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 125.2895 125.2895 20.5955 0.0001
strain 4 203.9245 50.9811 8.3805 0.0001
sex:strain 4 89.4264 22.3566 3.6751 0.0158
Residuals 28 170.3333 6.0833


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 140.0 0.957   4 0.479 0.00685 139.0, 141.0 -1.32
129S1/SvImJ m 147.0 2.5   4 1.25 0.017 144.0, 150.0 0.21
A/J f 149.0 4.55   4 2.27 0.0305 144.0, 155.0 1.14
A/J m 150.0 2.52   4 1.26 0.0167 147.0, 153.0 1.11
C57BL/6J f 146.0 1.73   4 0.866 0.0119 144.0, 147.0 0.32
C57BL/6J m 149.0 3.56   4 1.78 0.0239 146.0, 154.0 0.81
NOD/ShiLtJ f 141.0 0.577   3 0.333 0.0041 140.0, 141.0 -1.05
NOD/ShiLtJ m 147.0 1.5   4 0.75 0.0102 146.0, 149.0 0.21
NZO/HlLtJ f 145.0 1.71   4 0.854 0.0118 143.0, 147.0 0.05
NZO/HlLtJ m 144.0 1.53   3 0.882 0.0106 143.0, 146.0 -0.68
PWK/PhJ m 140.0 0.0   1   0.0 0.0 140.0, 140.0 -1.88
WSB/EiJ f 148.0 0.0   1   0.0 0.0 148.0, 148.0 0.87
WSB/EiJ m 147.0 3.21   3 1.86 0.0219 143.0, 149.0 0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 139.75 1.2332 142.2761 137.2239
129S1/SvImJ m 147.25 1.2332 149.7761 144.7239
A/J f 149.0 1.2332 151.5261 146.4739
A/J m 150.5 1.2332 153.0261 147.9739
C57BL/6J f 145.5 1.2332 148.0261 142.9739
C57BL/6J m 149.0 1.2332 151.5261 146.4739
NOD/ShiLtJ f 140.6667 1.424 143.5836 137.7497
NOD/ShiLtJ m 147.25 1.2332 149.7761 144.7239
NZO/HlLtJ f 145.25 1.2332 147.7761 142.7239
NZO/HlLtJ m 144.3333 1.424 147.2503 141.4164


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 143.5 0.872 145.2862 141.7138
A/J both 149.75 0.872 151.5362 147.9638
C57BL/6J both 147.25 0.872 149.0362 145.4638
NOD/ShiLtJ both 143.9583 0.9419 145.8877 142.029
NZO/HlLtJ both 144.7917 0.9419 146.721 142.8623




  GWAS USING LINEAR MIXED MODELS