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Project measure / variable:   GMC16   phosphate_21

ID, description, units MPD:56521   phosphate_21   phosphorus (plasma phosphate)   [mmol/L]  at age 20-21wks  
Data set, strains GMC16   inbred w/CC8   8 strains     sex: both     age: 20-21wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC16 - phosphorus (plasma phosphate) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means1.48   mmol/L 1.44   mmol/L
Median of the strain means1.40   mmol/L 1.35   mmol/L
SD of the strain means± 0.486 ± 0.400
Coefficient of variation (CV)0.327 0.278
Min–max range of strain means0.912   –   2.57   mmol/L 1.08   –   2.30   mmol/L
Mean sample size per strain10.1   mice 11.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0721 0.0721 0.4096 0.5231
strain 7 27.1942 3.8849 22.085 < 0.0001
sex:strain 7 2.1767 0.311 1.7677 0.0973
Residuals 158 27.7932 0.1759


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.912 0.182   10 0.0576 0.2 0.67, 1.27 -1.18
129S1/SvImJ m 1.1 0.295   12 0.0852 0.27 0.65, 1.5 -0.85
A/J f 2.57 0.708   10 0.224 0.275 1.5, 3.61 2.24
A/J m 2.3 0.489   11 0.147 0.212 1.5, 3.13 2.15
C57BL/6J f 1.39 0.485   10 0.153 0.349 0.7, 2.2 -0.19
C57BL/6J m 1.63 0.547   12 0.158 0.335 1.02, 2.5 0.47
CAST/EiJ f 1.18 0.448   12 0.129 0.379 0.62, 2.2 -0.63
CAST/EiJ m 1.08 0.169   11 0.051 0.156 0.78, 1.36 -0.9
NOD/ShiLtJ f 1.55 0.594   9 0.198 0.383 0.86, 2.7 0.14
NOD/ShiLtJ m 1.19 0.433   12 0.125 0.363 0.8, 2.08 -0.62
NZO/HlLtJ f 1.32 0.185   10 0.0585 0.14 1.1, 1.68 -0.34
NZO/HlLtJ m 1.51 0.444   12 0.128 0.294 0.83, 2.3 0.17
PWK/PhJ f 1.4 0.349   10 0.11 0.25 0.99, 1.9 -0.17
PWK/PhJ m 1.45 0.274   11 0.0825 0.189 1.0, 1.83 0.02
WSB/EiJ f 1.55 0.411   10 0.13 0.266 0.9, 2.25 0.14
WSB/EiJ m 1.26 0.302   12 0.0873 0.239 0.94, 1.9 -0.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.912 0.1326 1.174 0.65
129S1/SvImJ m 1.095 0.1211 1.3341 0.8559
A/J f 2.574 0.1326 2.836 2.312
A/J m 2.3027 0.1265 2.5525 2.053
C57BL/6J f 1.39 0.1326 1.652 1.128
C57BL/6J m 1.6317 0.1211 1.8708 1.3925
CAST/EiJ f 1.1825 0.1211 1.4216 0.9434
CAST/EiJ m 1.0827 0.1265 1.3325 0.833
NOD/ShiLtJ f 1.5522 0.1398 1.8283 1.2761
NOD/ShiLtJ m 1.1917 0.1211 1.4308 0.9525
NZO/HlLtJ f 1.323 0.1326 1.585 1.061
NZO/HlLtJ m 1.5108 0.1211 1.75 1.2717
PWK/PhJ f 1.396 0.1326 1.658 1.134
PWK/PhJ m 1.4473 0.1265 1.697 1.1975
WSB/EiJ f 1.546 0.1326 1.808 1.284
WSB/EiJ m 1.265 0.1211 1.5041 1.0259


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.0035 0.0898 1.1808 0.8262
A/J both 2.4384 0.0916 2.6193 2.2574
C57BL/6J both 1.5108 0.0898 1.6882 1.3335
CAST/EiJ both 1.1326 0.0875 1.3055 0.9597
NOD/ShiLtJ both 1.3719 0.0925 1.5546 1.1893
NZO/HlLtJ both 1.4169 0.0898 1.5943 1.2396
PWK/PhJ both 1.4216 0.0916 1.6026 1.2407
WSB/EiJ both 1.4055 0.0898 1.5828 1.2282




  GWAS USING LINEAR MIXED MODELS