Project measure / variable:   GMC16   lactate_21

ID, description, units MPD:56519   lactate_21   lactate (plasma)   [mmol/L]  at age 20-21wks  
Data set, strains GMC16   inbred w/CC8   8 strains     sex: both     age: 20-21wks
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  STRAIN COMPARISON PLOT
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GMC16 - lactate (plasma) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means8.25   mmol/L 9.36   mmol/L
Median of the strain means8.02   mmol/L 9.49   mmol/L
SD of the strain means± 2.48 ± 2.58
Coefficient of variation (CV)0.300 0.276
Min–max range of strain means5.16   –   13.2   mmol/L 5.33   –   14.0   mmol/L
Mean sample size per strain10.1   mice 11.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 61.5057 61.5057 11.6827 0.0008
strain 7 951.6223 135.946 25.8222 < 0.0001
sex:strain 7 17.6361 2.5194 0.4786 0.8491
Residuals 158 831.8209 5.2647


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.27 1.96   10 0.619 0.269 4.17, 9.35 -0.4
129S1/SvImJ m 9.45 3.31   12 0.954 0.35 5.36, 14.6 0.04
A/J f 13.2 1.85   10 0.584 0.14 9.93, 15.5 2.0
A/J m 14.0 2.75   11 0.83 0.196 8.92, 18.1 1.8
C57BL/6J f 9.06 1.79   10 0.565 0.197 6.39, 11.3 0.33
C57BL/6J m 9.53 2.87   12 0.827 0.301 5.19, 13.0 0.07
CAST/EiJ f 5.16 0.804   12 0.232 0.156 4.21, 6.86 -1.25
CAST/EiJ m 5.33 1.51   11 0.454 0.283 3.75, 8.11 -1.56
NOD/ShiLtJ f 9.32 3.07   9 1.02 0.33 5.09, 14.2 0.43
NOD/ShiLtJ m 11.2 3.38   12 0.975 0.302 6.59, 17.0 0.71
NZO/HlLtJ f 7.38 1.37   10 0.435 0.186 5.59, 9.87 -0.35
NZO/HlLtJ m 8.2 1.85   12 0.534 0.226 5.46, 12.8 -0.45
PWK/PhJ f 8.66 1.35   10 0.428 0.156 6.6, 11.0 0.16
PWK/PhJ m 9.77 2.38   11 0.719 0.244 5.38, 12.4 0.16
WSB/EiJ f 5.96 1.51   10 0.478 0.254 3.61, 7.86 -0.92
WSB/EiJ m 7.37 2.57   12 0.741 0.349 4.33, 13.7 -0.77


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.27 0.7256 8.7031 5.8369
129S1/SvImJ m 9.4483 0.6624 10.7566 8.1401
A/J f 13.161 0.7256 14.5941 11.7279
A/J m 14.0418 0.6918 15.4082 12.6754
C57BL/6J f 9.057 0.7256 10.4901 7.6239
C57BL/6J m 9.5342 0.6624 10.8424 8.2259
CAST/EiJ f 5.1575 0.6624 6.4657 3.8493
CAST/EiJ m 5.3291 0.6918 6.6955 3.9627
NOD/ShiLtJ f 9.3189 0.7648 10.8295 7.8083
NOD/ShiLtJ m 11.1833 0.6624 12.4916 9.8751
NZO/HlLtJ f 7.384 0.7256 8.8171 5.9509
NZO/HlLtJ m 8.1967 0.6624 9.5049 6.8884
PWK/PhJ f 8.657 0.7256 10.0901 7.2239
PWK/PhJ m 9.7736 0.6918 11.14 8.4072
WSB/EiJ f 5.958 0.7256 7.3911 4.5249
WSB/EiJ m 7.3675 0.6624 8.6757 6.0593


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.3592 0.4912 9.3294 7.389
A/J both 13.6014 0.5013 14.5915 12.6114
C57BL/6J both 9.2956 0.4912 10.2658 8.3254
CAST/EiJ both 5.2433 0.4789 6.1891 4.2974
NOD/ShiLtJ both 10.2511 0.5059 11.2503 9.2519
NZO/HlLtJ both 7.7903 0.4912 8.7605 6.8201
PWK/PhJ both 9.2153 0.5013 10.2054 8.2253
WSB/EiJ both 6.6627 0.4912 7.633 5.6925




  GWAS USING LINEAR MIXED MODELS