Project measure / variable:   GMC16   iron_binding_21

ID, description, units MPD:56516   iron_binding_21   unsaturated iron binding capacity (plasma UIBC)   [µmol/L]  
Data set, strains GMC16   inbred w/CC8   6 strains     sex: both
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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GMC16 - unsaturated iron binding capacity (plasma UIBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means26.5   µmol/L 31.4   µmol/L
Median of the strain means26.4   µmol/L 30.4   µmol/L
SD of the strain means± 5.63 ± 2.96
Coefficient of variation (CV)0.212 0.0943
Min–max range of strain means20.5   –   35.8   µmol/L 28.4   –   36.5   µmol/L
Mean sample size per strain2.3   mice 3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 140.8209 140.8209 3.4649 0.0767
strain 4 310.1126 77.5281 1.9076 0.1466
sex:strain 4 41.6328 10.4082 0.2561 0.9027
Residuals 21 853.4873 40.6423


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 21.4 5.73   2   4.05 0.268 17.3, 25.4 -0.91
129S1/SvImJ m 28.4 1.1   3 0.636 0.0388 27.3, 29.5 -1.01
A/J f 28.2 3.61   2   2.55 0.128 25.7, 30.8 0.3
A/J m 29.8 2.32   3 1.34 0.0776 27.9, 32.4 -0.54
C57BL/6J f 28.5 0.919   2   0.65 0.0323 27.8, 29.1 0.35
C57BL/6J m 33.1 3.18   3 1.84 0.0959 29.5, 35.4 0.57
NOD/ShiLtJ f 20.5 0.0   1   0.0 0.0 20.5, 20.5 -1.07
NOD/ShiLtJ m 29.6 1.81   3 1.05 0.0612 27.7, 31.3 -0.61
NZO/HlLtJ f 35.8 3.61   2   2.55 0.101 33.3, 38.4 1.65
NZO/HlLtJ m 36.5 1.34   2   0.95 0.0368 35.6, 37.5 1.72
PWK/PhJ f 24.7 6.82   5 3.05 0.276 18.4, 32.2 -0.32
PWK/PhJ m 31.0 9.77   7 3.69 0.315 18.2, 46.9 -0.14


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 21.35 4.5079 30.7247 11.9753
129S1/SvImJ m 28.3667 3.6807 36.0211 20.7123
A/J f 28.25 4.5079 37.6247 18.8753
A/J m 29.8333 3.6807 37.4877 22.1789
C57BL/6J f 28.45 4.5079 37.8247 19.0753
C57BL/6J m 33.1333 3.6807 40.7877 25.4789
NZO/HlLtJ f 35.85 4.5079 45.2247 26.4753
NZO/HlLtJ m 36.55 4.5079 45.9247 27.1753
PWK/PhJ f 24.72 2.851 30.6491 18.7909
PWK/PhJ m 31.0286 2.4096 36.0396 26.0176


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 24.8583 2.9098 30.9097 18.807
A/J both 29.0417 2.9098 35.093 22.9903
C57BL/6J both 30.7917 2.9098 36.843 24.7403
NZO/HlLtJ both 36.2 3.1876 42.8289 29.5711
PWK/PhJ both 27.8743 1.8664 31.7558 23.9928




  GWAS USING LINEAR MIXED MODELS