Project measure / variable:   GMC16   chloride_17

ID, description, units MPD:56512   chloride_17   chloride (plasma Cl)   [mmol/L]  at age 16-17wks  
Data set, strains GMC16   inbred w/CC8   7 strains     sex: both     age: 16-17wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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GMC16 - chloride (plasma Cl) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means110   mmol/L 108   mmol/L
Median of the strain means110   mmol/L 110   mmol/L
SD of the strain means± 3.50 ± 3.60
Coefficient of variation (CV)0.0319 0.0332
Min–max range of strain means105   –   114   mmol/L 103   –   113   mmol/L
Mean sample size per strain3.3   mice 3.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2063 0.2063 0.0651 0.8005
strain 4 226.5533 56.6383 17.8596 < 0.0001
sex:strain 4 57.4984 14.3746 4.5327 0.006
Residuals 28 88.7967 3.1713


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 108.0 1.18   4 0.592 0.0109 108.0, 110.0 -0.48
129S1/SvImJ m 110.0 1.16   4 0.578 0.0105 109.0, 111.0 0.44
A/J f 112.0 2.26   4 1.13 0.0201 109.0, 115.0 0.67
A/J m 113.0 2.27   4 1.14 0.0201 111.0, 116.0 1.27
C57BL/6J f 112.0 1.61   4 0.807 0.0144 110.0, 114.0 0.67
C57BL/6J m 110.0 1.95   4 0.975 0.0177 108.0, 112.0 0.44
NOD/ShiLtJ f 105.0 1.34   3 0.775 0.0128 104.0, 107.0 -1.33
NOD/ShiLtJ m 109.0 0.963   4 0.481 0.00886 107.0, 110.0 0.16
NZO/HlLtJ f 107.0 1.15   4 0.576 0.0107 106.0, 109.0 -0.76
NZO/HlLtJ m 104.0 3.17   3 1.83 0.0305 102.0, 108.0 -1.23
PWK/PhJ m 103.0 0.0   1   0.0 0.0 103.0, 103.0 -1.51
WSB/EiJ f 114.0 0.0   1   0.0 0.0 114.0, 114.0 1.24
WSB/EiJ m 110.0 3.13   3 1.81 0.0286 106.0, 112.0 0.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 108.475 0.8904 110.2989 106.6511
129S1/SvImJ m 110.25 0.8904 112.0739 108.4261
A/J f 112.375 0.8904 114.1989 110.5511
A/J m 112.875 0.8904 114.6989 111.0511
C57BL/6J f 112.125 0.8904 113.9489 110.3011
C57BL/6J m 109.95 0.8904 111.7739 108.1261
NOD/ShiLtJ f 105.0667 1.0282 107.1727 102.9606
NOD/ShiLtJ m 108.7 0.8904 110.5239 106.8761
NZO/HlLtJ f 107.3 0.8904 109.1239 105.4761
NZO/HlLtJ m 104.0 1.0282 106.1061 101.8939


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 109.3625 0.6296 110.6522 108.0728
A/J both 112.625 0.6296 113.9147 111.3353
C57BL/6J both 111.0375 0.6296 112.3272 109.7478
NOD/ShiLtJ both 106.8833 0.6801 108.2764 105.4903
NZO/HlLtJ both 105.65 0.6801 107.043 104.257




  GWAS USING LINEAR MIXED MODELS