Project measure / variable:   GMC16   calcium_21

ID, description, units MPD:56511   calcium_21   calcium (plasma Ca)   [mmol/L]  at age 20-21wks  
Data set, strains GMC16   inbred w/CC8   8 strains     sex: both     age: 20-21wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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GMC16 - calcium (plasma Ca) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means2.42   mmol/L 2.41   mmol/L
Median of the strain means2.41   mmol/L 2.41   mmol/L
SD of the strain means± 0.0664 ± 0.0736
Coefficient of variation (CV)0.0274 0.0306
Min–max range of strain means2.33   –   2.52   mmol/L 2.33   –   2.51   mmol/L
Mean sample size per strain10.1   mice 11.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0037 0.0037 0.4155 0.5201
strain 7 0.7097 0.1014 11.2421 < 0.0001
sex:strain 7 0.038 0.0054 0.6026 0.7531
Residuals 158 1.4248 0.009


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.52 0.0894   10 0.0283 0.0355 2.37, 2.66 1.49
129S1/SvImJ m 2.51 0.184   12 0.0531 0.0733 2.34, 3.0 1.39
A/J f 2.45 0.0527   10 0.0167 0.0215 2.37, 2.53 0.43
A/J m 2.43 0.0787   11 0.0237 0.0324 2.26, 2.53 0.31
C57BL/6J f 2.41 0.0709   10 0.0224 0.0294 2.29, 2.52 -0.17
C57BL/6J m 2.38 0.0651   12 0.0188 0.0274 2.28, 2.49 -0.37
CAST/EiJ f 2.35 0.0566   12 0.0164 0.0241 2.26, 2.48 -1.07
CAST/EiJ m 2.33 0.0815   11 0.0246 0.0349 2.23, 2.47 -1.05
NOD/ShiLtJ f 2.41 0.161   9 0.0537 0.0669 2.15, 2.59 -0.17
NOD/ShiLtJ m 2.44 0.0985   12 0.0284 0.0403 2.28, 2.61 0.44
NZO/HlLtJ f 2.5 0.08   10 0.0253 0.0321 2.35, 2.66 1.19
NZO/HlLtJ m 2.5 0.105   12 0.0302 0.0418 2.32, 2.65 1.26
PWK/PhJ f 2.4 0.0987   10 0.0312 0.041 2.23, 2.51 -0.32
PWK/PhJ m 2.33 0.0778   11 0.0235 0.0334 2.2, 2.44 -1.05
WSB/EiJ f 2.33 0.0426   10 0.0135 0.0183 2.26, 2.41 -1.37
WSB/EiJ m 2.34 0.0627   12 0.0181 0.0268 2.23, 2.46 -0.92


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.518 0.03 2.5773 2.4587
129S1/SvImJ m 2.5075 0.0274 2.5616 2.4534
A/J f 2.447 0.03 2.5063 2.3877
A/J m 2.4282 0.0286 2.4847 2.3716
C57BL/6J f 2.411 0.03 2.4703 2.3517
C57BL/6J m 2.3783 0.0274 2.4325 2.3242
CAST/EiJ f 2.3492 0.0274 2.4033 2.295
CAST/EiJ m 2.3327 0.0286 2.3893 2.2762
NOD/ShiLtJ f 2.41 0.0317 2.4725 2.3475
NOD/ShiLtJ m 2.4433 0.0274 2.4975 2.3892
NZO/HlLtJ f 2.496 0.03 2.5553 2.4367
NZO/HlLtJ m 2.5025 0.0274 2.5566 2.4484
PWK/PhJ f 2.404 0.03 2.4633 2.3447
PWK/PhJ m 2.3309 0.0286 2.3875 2.2744
WSB/EiJ f 2.328 0.03 2.3873 2.2687
WSB/EiJ m 2.3408 0.0274 2.395 2.2867


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.5127 0.0203 2.5529 2.4726
A/J both 2.4376 0.0207 2.4786 2.3966
C57BL/6J both 2.3947 0.0203 2.4348 2.3545
CAST/EiJ both 2.3409 0.0198 2.3801 2.3018
NOD/ShiLtJ both 2.4267 0.0209 2.468 2.3853
NZO/HlLtJ both 2.4992 0.0203 2.5394 2.4591
PWK/PhJ both 2.3675 0.0207 2.4084 2.3265
WSB/EiJ both 2.3344 0.0203 2.3746 2.2943




  GWAS USING LINEAR MIXED MODELS