Project measure / variable:   GMC12   LVPW_systole

ID, description, units MPD:56136   LVPW_systole   left ventricular posterior wall width   [mm]  systole  
Data set, strains GMC12   inbred w/CC8   8 strains     sex: both     age: 14-15wks
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  STRAIN COMPARISON PLOT
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GMC12 - left ventricular posterior wall width systole



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means0.549   mm 0.552   mm
Median of the strain means0.544   mm 0.546   mm
SD of the strain means± 0.0275 ± 0.0339
Coefficient of variation (CV)0.0501 0.0614
Min–max range of strain means0.518   –   0.605   mm 0.503   –   0.621   mm
Mean sample size per strain17.1   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0006 0.0006 0.1427 0.7059
strain 7 0.2099 0.03 6.6963 < 0.0001
sex:strain 7 0.0145 0.0021 0.4616 0.8617
Residuals 252 1.1286 0.0045


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.54 0.0647   16 0.0162 0.12 0.43, 0.66 -0.34
129S1/SvImJ m 0.553 0.0674   16 0.0169 0.122 0.46, 0.69 0.03
A/J f 0.539 0.041   15 0.0106 0.0762 0.46, 0.59 -0.37
A/J m 0.539 0.0528   16 0.0132 0.098 0.46, 0.63 -0.38
C57BL/6J f 0.561 0.0652   16 0.0163 0.116 0.48, 0.7 0.43
C57BL/6J m 0.57 0.0728   16 0.0182 0.128 0.45, 0.7 0.54
CAST/EiJ f 0.522 0.0618   19 0.0142 0.118 0.38, 0.64 -0.99
CAST/EiJ m 0.541 0.0579   14 0.0155 0.107 0.46, 0.63 -0.32
NOD/ShiLtJ f 0.548 0.046   18 0.0109 0.084 0.44, 0.63 -0.05
NOD/ShiLtJ m 0.552 0.041   16 0.0103 0.0743 0.48, 0.64 0.0
NZO/HlLtJ f 0.605 0.0866   17 0.021 0.143 0.44, 0.8 2.03
NZO/HlLtJ m 0.621 0.0606   17 0.0147 0.0976 0.5, 0.75 2.04
PWK/PhJ f 0.561 0.0924   19 0.0212 0.165 0.42, 0.71 0.43
PWK/PhJ m 0.536 0.0786   20 0.0176 0.146 0.38, 0.67 -0.47
WSB/EiJ f 0.518 0.0744   17 0.018 0.143 0.43, 0.74 -1.14
WSB/EiJ m 0.503 0.0717   16 0.0179 0.143 0.4, 0.66 -1.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.54 0.0167 0.5729 0.5071
129S1/SvImJ m 0.5531 0.0167 0.5861 0.5202
A/J f 0.5387 0.0173 0.5727 0.5046
A/J m 0.5394 0.0167 0.5723 0.5064
C57BL/6J f 0.5613 0.0167 0.5942 0.5283
C57BL/6J m 0.57 0.0167 0.6029 0.5371
CAST/EiJ f 0.5216 0.0154 0.5518 0.4913
CAST/EiJ m 0.5414 0.0179 0.5767 0.5062
NOD/ShiLtJ f 0.5483 0.0158 0.5794 0.5173
NOD/ShiLtJ m 0.5519 0.0167 0.5848 0.5189
NZO/HlLtJ f 0.6053 0.0162 0.6373 0.5733
NZO/HlLtJ m 0.6206 0.0162 0.6526 0.5886
PWK/PhJ f 0.5605 0.0154 0.5908 0.5303
PWK/PhJ m 0.5365 0.015 0.566 0.507
WSB/EiJ f 0.5182 0.0162 0.5502 0.4863
WSB/EiJ m 0.5031 0.0167 0.5361 0.4702


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.5466 0.0118 0.5699 0.5233
A/J both 0.539 0.012 0.5627 0.5153
C57BL/6J both 0.5656 0.0118 0.5889 0.5423
CAST/EiJ both 0.5315 0.0118 0.5547 0.5083
NOD/ShiLtJ both 0.5501 0.0115 0.5727 0.5275
NZO/HlLtJ both 0.6129 0.0115 0.6355 0.5903
PWK/PhJ both 0.5485 0.0107 0.5696 0.5274
WSB/EiJ both 0.5107 0.0117 0.5336 0.4877




  GWAS USING LINEAR MIXED MODELS