Project measure / variable:   GMC11   GLU_120

ID, description, units MPD:56015   GLU_120   intraperitoneal glucose tolerance test (20% glucose i.p., 16h fast)   [mmol/L]  at 120 min  
Data set, strains GMC11   inbred   6 strains     sex: both     age: 13-14wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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GMC11 - intraperitoneal glucose tolerance test (20% glucose i.p., 16h fast) at 120 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means9.28   mmol/L 10.9   mmol/L
Median of the strain means8.01   mmol/L 8.39   mmol/L
SD of the strain means± 4.98 ± 6.89
Coefficient of variation (CV)0.536 0.630
Min–max range of strain means5.78   –   19.2   mmol/L 6.24   –   24.8   mmol/L
Mean sample size per strain13.8   mice 15.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 98.762 98.762 9.3671 0.0026
strain 4 5531.8539 1382.9635 131.1672 < 0.0001
sex:strain 4 265.4612 66.3653 6.2944 0.0001
Residuals 152 1602.6143 10.5435


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 6.28 1.45   16 0.361 0.23 4.11, 8.83 -0.6
129S1/SvImJ m 8.68 1.52   16 0.38 0.175 5.94, 11.8 -0.33
A/J f 5.78 0.776   15 0.2 0.134 4.05, 6.83 -0.7
A/J m 8.11 2.11   16 0.527 0.26 4.27, 13.2 -0.41
C57BL/6J f 7.8 0.888   16 0.222 0.114 6.38, 9.82 -0.3
C57BL/6J m 7.94 1.05   16 0.263 0.133 6.44, 10.4 -0.44
NOD/ShiLtJ f 8.22 6.77   18 1.6 0.824 3.77, 27.2 -0.21
NOD/ShiLtJ m 6.24 1.1   16 0.276 0.177 4.72, 8.49 -0.68
NZO/HlLtJ f 19.2 3.84   17 0.933 0.201 12.3, 25.3 1.99
NZO/HlLtJ m 24.8 5.15   16 1.29 0.208 10.6, 33.2 2.01
PWK/PhJ f 8.38 0.0   1   0.0 0.0 8.38, 8.38 -0.18
PWK/PhJ m 9.86 1.96   12 0.567 0.199 7.1, 12.9 -0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 6.28 0.8118 7.8838 4.6762
129S1/SvImJ m 8.6781 0.8118 10.2819 7.0743
A/J f 5.78 0.8384 7.4364 4.1236
A/J m 8.1131 0.8118 9.7169 6.5093
C57BL/6J f 7.7981 0.8118 9.4019 6.1943
C57BL/6J m 7.9375 0.8118 9.5413 6.3337
NOD/ShiLtJ f 8.22 0.7653 9.7321 6.7079
NOD/ShiLtJ m 6.2406 0.8118 7.8444 4.6368
NZO/HlLtJ f 19.1724 0.7875 20.7283 17.6164
NZO/HlLtJ m 24.7563 0.8118 26.3601 23.1524


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.4791 0.574 8.6131 6.345
A/J both 6.9466 0.5835 8.0994 5.7938
C57BL/6J both 7.8678 0.574 9.0019 6.7337
NOD/ShiLtJ both 7.2303 0.5578 8.3324 6.1282
NZO/HlLtJ both 21.9643 0.5655 23.0816 20.847




  GWAS USING LINEAR MIXED MODELS