Project measure / variable:   GMC11   GLU_60

ID, description, units MPD:56014   GLU_60   intraperitoneal glucose tolerance test (20% glucose i.p., 16h fast)   [mmol/L]  at 60 min  
Data set, strains GMC11   inbred   6 strains     sex: both     age: 13-14wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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GMC11 - intraperitoneal glucose tolerance test (20% glucose i.p., 16h fast) at 60 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means14.0   mmol/L 16.9   mmol/L
Median of the strain means13.2   mmol/L 15.4   mmol/L
SD of the strain means± 6.34 ± 5.56
Coefficient of variation (CV)0.452 0.328
Min–max range of strain means8.60   –   26.1   mmol/L 12.6   –   27.5   mmol/L
Mean sample size per strain13.8   mice 14.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 147.4402 147.4402 9.8954 0.002
strain 4 4557.3361 1139.334 76.4662 < 0.0001
sex:strain 4 219.8809 54.9702 3.6893 0.0068
Residuals 148 2205.1756 14.8998


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 8.6 1.65   16 0.414 0.192 6.22, 12.2 -0.85
129S1/SvImJ m 13.2 3.39   16 0.848 0.257 8.33, 19.8 -0.67
A/J f 12.4 2.6   15 0.672 0.21 7.05, 16.0 -0.26
A/J m 17.6 3.72   16 0.93 0.212 9.77, 23.5 0.12
C57BL/6J f 13.9 1.84   16 0.461 0.132 10.9, 17.6 -0.02
C57BL/6J m 17.0 1.64   16 0.411 0.0965 14.6, 21.1 0.01
NOD/ShiLtJ f 13.9 8.51   18 2.01 0.614 4.88, 32.7 -0.02
NOD/ShiLtJ m 12.6 2.16   16 0.54 0.171 8.88, 16.8 -0.78
NZO/HlLtJ f 26.1 3.51   17 0.85 0.134 19.9, 32.2 1.91
NZO/HlLtJ m 27.5 3.02   12 0.873 0.11 22.0, 32.9 1.9
PWK/PhJ f 9.21 0.0   1   0.0 0.0 9.21, 9.21 -0.76
PWK/PhJ m 13.8 2.78   12 0.802 0.202 9.05, 18.5 -0.57


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 8.6006 0.965 10.5076 6.6937
129S1/SvImJ m 13.1837 0.965 15.0907 11.2768
A/J f 12.404 0.9967 14.3735 10.4345
A/J m 17.5812 0.965 19.4882 15.6743
C57BL/6J f 13.9462 0.965 15.8532 12.0393
C57BL/6J m 17.0375 0.965 18.9445 15.1305
NOD/ShiLtJ f 13.8572 0.9098 15.6551 12.0593
NOD/ShiLtJ m 12.6281 0.965 14.5351 10.7212
NZO/HlLtJ f 26.1494 0.9362 27.9994 24.2994
NZO/HlLtJ m 27.5033 1.1143 29.7053 25.3014


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 10.8922 0.6824 12.2406 9.5438
A/J both 14.9926 0.6936 16.3633 13.6219
C57BL/6J both 15.4919 0.6824 16.8403 14.1434
NOD/ShiLtJ both 13.2427 0.6631 14.5531 11.9322
NZO/HlLtJ both 26.8264 0.7277 28.2644 25.3884




  GWAS USING LINEAR MIXED MODELS